AUTHOR=Alcouffe Leslie , Huber Florence , Creton Pierre-Marie , Bitan Luana , Gonzalez Adriana , Volpellier Muriel , Panfili Biancaelena , Adenis Antoine , Vignier Nicolas TITLE=Sexual vulnerability of migrant women in the multicultural context of French Guiana: A societal issue JOURNAL=Frontiers in Public Health VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.934049 DOI=10.3389/fpubh.2022.934049 ISSN=2296-2565 ABSTRACT=Background : French Guiana is a multicultural French territory in Amazonia with an old migration history and a high prevalence of HIV infection. The objective of this study was to evaluate situations of sexual vulnerability and their associated factors among migrant women in French Guiana. Methods : A cross-sectional epidemiological study was carried out in 2021 in the French Red Cross Prevention and Health Centers of the two main cities of French Guiana (Cayenne and Saint Laurent du Maroni). Analysis has been performed with multivariate stepwise logistic regression with Stata 15.1 software. Findings : A total of 382 migrant women have been included, aged in median of 31 years, mainly born in Haiti (80%), Suriname (9%) or Dominican Republic (6%), undocumented (71%) and with financial difficulties (77%). Among the 20% having casual partners, 57% reports unprotected sexual intercourse, more often Haitian and Surinamese women. An history of rape was reported by 20% of women, most often in the country of origin (71%). Lifetime rape was associated with being threatened aOR=3.69 [1.96-6.96] or being physically abused aOR = 12.95 [6.51-25.75] in the multivariate analysis. Among the women surveyed, 30% reported having ever exchanged sex for money, food, or shelter in their lifetime. Transactional sex is more common among Dominican women (aOR = 5,59[1,84-16,95]) and women living in French Guiana for more than 2 years (aOR = 2,32[1,38-3,92]). Transactional sex is also associated with alcohol misuse (aOR=2,57[1,46-4,53]), history of threats (aOR=2,03[1,14-3,63]), history of rape (aOR=1,92[1,03-3,60]) and mood disorders (aOR=2,08[1,21-3,60]). Interpretation : Migrant women in French Guiana are in a situation of sexual vulnerability. An intervention focused on sexual education and the promotion of prevention tools to Haitian women is advisable. Better prevention and support for transactional sex is needed to prevent violence and its mental health and alcohol misuse consequences for all women, especially Dominican women.