AUTHOR=Du Shihong , Hong Xiuqin , Yang Yi , Ding Zihao , Yu Tong 

TITLE=Association between body fat percentage and H-type hypertension in postmenopausal women

JOURNAL=Frontiers in Public Health

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.950805

DOI=10.3389/fpubh.2022.950805

ISSN=2296-2565

ABSTRACT=Background: Previous studies have explored the relationship between body fat percentage (BFP) and hypertension or homocysteine. However, evidence on the constancy of the association remains inconclusive in postmenopausal women. The aim of this study was to investigate the association between BFP and H-type hypertension in postmenopausal women.
Methods: This cross-sectional study included 1597 eligible female patients with hypertension. Homocysteine levels ≥10 mmol/L were defined as H-type hypertension. BFP was calculated by measuring patients' physical parameters. Subjects were divided into 4 groups according to quartiles of BFP（Q1: 33.4% or lower , Q2: 33.4%-36.1% , Q3: 36.1%-39.1% , Q4: greater than 39.1%）. We used restricted cubic spline regression models and logistic regression analysis to assess the relationship between BFP and H-type hypertension. Additional subgroup analysis was performed for this study.
Results: Among 1597 hypertensive patients, 955 (59.8%) participants had H-type hypertension. There were significant differences between the two groups in age, BMI, educational background, marital status, exercise status, drinking history, WC, TG, LDL, Scr, BUN, and eGFR (P<0.05). The prevalence of H-type hypertension in the Q1 to Q4 groups was 24.9%, 25.1%, 24.9%, and 25.1%, respectively. After adjusting for relevant factors, we found that the risk of H-type hypertension in the Q4 group had a significantly higher than the Q1 group (OR=3.2, 95% CI: 1.3-7.5).
Conclusion: BFP was positively associated with the risk of H-type hypertension in postmenopausal women. Postmenopausal women should control body fat to prevent hypertension.