AUTHOR=Zhang Wenjing , Li Zinan , Li Guojun , Kong Ling , Jing Haiming , Zhang Nan , Ning Junyu , Gao Shan , Zhang Yong , Wang Xinyu , Tao Jing 

TITLE=PM2.5 induce lifespan reduction, insulin/IGF-1 signaling pathway disruption and lipid metabolism disorder in Caenorhabditis elegans

JOURNAL=Frontiers in Public Health

VOLUME=Volume 11 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1055175

DOI=10.3389/fpubh.2023.1055175

ISSN=2296-2565

ABSTRACT=Exposure to fine particulate matter (PM), especially PM2.5, can induce various adverse effects on health, including diseases and premature death in populations. In the present study, water-soluble components of PM2.5 (WS-PM2.5) were collected in north China in winter, and combined in two groups with the final concentrations of 94 μg/mL (low concentration group, AQI ≤ 100) and 119 μg/mL (high concentration group, 100