AUTHOR=Abeysuriya Romesh G. , Sacks-Davis Rachel , Heath Katherine , Delport Dominic , Russell Fiona M. , Danchin Margie , Hellard Margaret , McVernon Jodie , Scott Nick TITLE=Keeping kids in school: modelling school-based testing and quarantine strategies during the COVID-19 pandemic in Australia JOURNAL=Frontiers in Public Health VOLUME=Volume 11 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1150810 DOI=10.3389/fpubh.2023.1150810 ISSN=2296-2565 ABSTRACT=Background: In 2021, the Australian Government Department of Health commissioned a consortium of modelling groups to generate evidence assisting the transition from a goal of no community COVID-19 transmission to ‘living with COVID-19’, with adverse health and social consequences limited by vaccination and other measures. Due to the extended school closures over 2020-21, maximising face-to-face teaching was a major objective during this transition. The consortium was tasked with informing school surveillance and contact management strategies to minimise infections and support this goal. Methods: Outcomes considered were infections and days of face-to-face teaching lost in the 45 days following an outbreak within an otherwise COVID-naïve school setting. A stochastic agent-based model of COVID-19 transmission was used to evaluate a ‘test-to-stay’ strategy using daily rapid antigen tests (RATs) for close contacts of a case for seven days compared with home quarantine; and an asymptomatic surveillance strategy involving twice-weekly screening of all students and/or teachers using RATs. Findings: Test-to-stay had similar effectiveness for reducing school infections as extended home quarantine, without the associated days of face-to-face teaching lost. Asymptomatic screening was beneficial in reducing both infections and days of face-to-face teaching lost and was most beneficial when community prevalence was high. Interpretation: Use of RATs in school settings for surveillance and contact management can help to maximise face-to-face teaching and minimise outbreaks. This evidence supported the implementation of surveillance testing in schools in several Australian jurisdictions from January 2022.