AUTHOR=Singh Priya , Anand Aditya , Rana Shweta , Kumar Amit , Goel Prabudh , Kumar Sujeet , Gouda Krushna Chandra , Singh Harpreet 

TITLE=Impact of COVID-19 vaccination: a global perspective

JOURNAL=Frontiers in Public Health

VOLUME=Volume 11 - 2023

YEAR=2024

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2023.1272961

DOI=10.3389/fpubh.2023.1272961

ISSN=2296-2565

ABSTRACT=ABSTRACT:
Introduction: The COVID-19 pandemic has caused widespread morbidity, mortality, and socio-economic disruptions worldwide. Vaccination has proven to be a crucial strategy in controlling the spread of the virus and mitigating its impact. 
Objective: The study focuses on assessing the effectiveness of COVID-19 vaccination in reducing the incidence of positive cases, hospitalizations and ICU admissions. The presented study is focused on the COVID-19 fully vaccinated population by considering the data from the first positive case reported till 20 September 2021. 
Methods: Using data from multiple countries, time-series analysis is deployed to investigate the variations in the COVID-19 positivity rate, hospitalization rate and ICU requirements, after suc-cessful vaccination campaign at country scale. 
Results: Analysis of the COVID-19 positivity rate revealed a substantial decline in countries with high pre-vaccination rates. Within one to three months of vaccination campaign, these rates decreased by 20% to 44%. However, certain countries experienced an increase in positivity rates with emergence of the new Delta variant, emphasizing the importance of ongoing monitoring and adaptable vaccination strategies. Similarly, the analysis of hospitalization rates demonstrated a steady decline as vaccination drive rates rose in various countries. Within 90 days of vaccination, several countries achieved hospitalization rates below 200 per million. However, a slight increase in hospitalizations was observed in some countries after 180 days of vaccination, underscoring the need for continued vigilance. Furthermore, the ICU patient rate decreased as vaccination rates increased across most countries. Within 120 days, several countries achieved an ICU patient rate of 20 per million, highlighting the effectiveness of vaccination in preventing severe cases requiring intensive care.
Conclusion:COVID-19 vaccination has proven to be very much effective in reducing the incidence of cases, hospitalizations and ICU admissions. However, ongoing surveillance, variant monitoring, and adaptive vaccination strategies are crucial for maximizing the benefits of vaccination and effectively controlling the spread of the virus.