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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2023.1302675</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>A reliable and valid tool to assess the sexual acceptability of contraceptive methods</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Lahoz-Pascual</surname>
<given-names>Isabel</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<contrib contrib-type="author">
<name>
<surname>Jurado-Lopez</surname>
<given-names>Ana Rosa</given-names>
</name>
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<contrib contrib-type="author">
<name>
<surname>Ju&#x00E1;rez-Vela</surname>
<given-names>Ra&#x00FA;l</given-names>
</name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
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<contrib contrib-type="author">
<name>
<surname>Santolalla-Arnedo</surname>
<given-names>Iv&#x00E1;n</given-names>
</name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
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<contrib contrib-type="author" corresp="yes">
<name>
<surname>Ruiz de Vi&#x00F1;aspre-Hern&#x00E1;ndez</surname>
<given-names>Regina</given-names>
</name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
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<contrib contrib-type="author">
<name>
<surname>Repoll&#x00E9;s-Lasheras</surname>
<given-names>Sira</given-names>
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<contrib contrib-type="author">
<name>
<surname>Tejero Sancho</surname>
<given-names>Susana</given-names>
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<contrib contrib-type="author">
<name>
<surname>Diaz-Vega</surname>
<given-names>Miguel</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
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<contrib contrib-type="author">
<name>
<surname>Lou-Mercade</surname>
<given-names>Ana Cristina</given-names>
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<contrib contrib-type="author">
<name>
<surname>Mendoza-Ladr&#x00F3;n de Guevara</surname>
<given-names>Nicol&#x00E1;s</given-names>
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<aff id="aff1"><sup>1</sup><institution>Department of Obstetrics and Gynecology, Hospital Cl&#x00ED;nico Universitario Lozano Blesa</institution>, <addr-line>Zaragoza</addr-line>, <country>Spain</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Obstetrics and Gynecology, University of Zaragoza</institution>, <addr-line>Zaragoza</addr-line>, <country>Spain</country></aff>
<aff id="aff3"><sup>3</sup><institution>Department of Obstetrics and Gynecology, University of Granada</institution>, <addr-line>Granada</addr-line>, <country>Spain</country></aff>
<aff id="aff4"><sup>4</sup><institution>Department of Nursing, University of La Rioja</institution>, <addr-line>Logro&#x00F1;o</addr-line>, <country>Spain</country></aff>
<aff id="aff5"><sup>5</sup><institution>Biomedical Research Center of a Rioja, CIBIR</institution>, <addr-line>Logro&#x00F1;o</addr-line>, <country>Spain</country></aff>
<author-notes>
<fn id="fn0001" fn-type="edited-by"><p>Edited by: Praveen Hoogar, The Apollo University, India</p></fn>
<fn id="fn0002" fn-type="edited-by"><p>Reviewed by: Maya Rathnasabapathy, Vellore Institute of Technology (VIT), India</p>
<p>Kabilan Annadurai, The Apollo University, India</p></fn>
<corresp id="c001">&#x002A;Correspondence: Regina Ruiz de Vi&#x00F1;aspre-Hern&#x00E1;ndez, <email>reruizde@unirioja.es</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>04</day>
<month>01</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>11</volume>
<elocation-id>1302675</elocation-id>
<history>
<date date-type="received">
<day>06</day>
<month>10</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>04</day>
<month>12</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2024 Lahoz-Pascual, Jurado-Lopez, Ju&#x00E1;rez-Vela, Santolalla-Arnedo, Ruiz de Vi&#x00F1;aspre-Hern&#x00E1;ndez, Repoll&#x00E9;s-Lasheras, Tejero Sancho, Diaz-Vega, Lou-Mercade and Mendoza-Ladr&#x00F3;n de Guevara.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Lahoz-Pascual, Jurado-Lopez, Ju&#x00E1;rez-Vela, Santolalla-Arnedo, Ruiz de Vi&#x00F1;aspre-Hern&#x00E1;ndez, Repoll&#x00E9;s-Lasheras, Tejero Sancho, Diaz-Vega, Lou-Mercade and Mendoza-Ladr&#x00F3;n de Guevara</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec id="sec1">
<title>Introduction</title>
<p>Adequate identification of the sexual acceptability of contraceptive methods is key for designing health promotion interventions, assessing their impacts, and increasing their effectiveness. This study aimed to develop and validate a questionnaire to explore the preferences of women depending on their epidemiological characteristics and their partner relationships&#x2014;the <italic>Sexual Acceptability of Contraceptive Methods Questionnaire</italic> [in Spanish, Aceptabilidad Sexual de los M&#x00E9;todos Anticonceptivos (ASMA)].</p>
</sec>
<sec id="sec2">
<title>Methods</title>
<p>Psychometric validation was conducted using Exploratory Factorial Analysis (EFA) and confirmatory factor analysis (CFA). The reliability of the final version of the questionnaire was explored using Cronbach&#x2019;s alpha and McDonald omega to estimate internal consistency.</p>
</sec>
<sec id="sec3">
<title>Results</title>
<p>A three-factor model was identified. Factor 1 (explaining 28.32% of the model) corresponds to questions concerning the use and placement of the contraceptive and includes 6 items; Factor 2 (explaining 24.23%) corresponds to other factors that affect the relationship such as bleeding and side effects of the contraceptive method and includes 10 items; and Factor 3 (explaining 18.94%) corresponds to the couple relationship and includes 8 items.</p>
</sec>
<sec id="sec4">
<title>Conclusion and implications</title>
<p>The ASMA questionnaire provides a valid and reliable tool for assessing the sexual acceptability of various contraceptive methods. This instrument gathers data that provide information on various aspects of women&#x2019;s sexuality, health, education, and beliefs, all of which can determine the preference for one contraceptive method over another. Moreover, the tool can help to identify profiles of women who have different preferences when selecting a particular method.</p>
</sec>
</abstract>
<kwd-group>
<kwd>questionnaire development</kwd>
<kwd>choice of contraceptive method</kwd>
<kwd>sexual acceptability</kwd>
<kwd>gynecology</kwd>
<kwd>obstetrics</kwd>
</kwd-group>
<counts>
<fig-count count="0"/>
<table-count count="5"/>
<equation-count count="0"/>
<ref-count count="15"/>
<page-count count="7"/>
<word-count count="4254"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Public Health Education and Promotion</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="sec5">
<title>Introduction</title>
<p>The aim of contraception is to avoid unwanted pregnancies and ensure a satisfactory sexual life free of procreative risks (<xref ref-type="bibr" rid="ref1">1</xref>). In Spain, the contraceptive method most commonly used by women in their sexual relations is the condom, followed by the pill. It is important to emphasize that there has been no change in the pattern of use since 1997 despite the marketing of many other types of more effective and comfortable contraceptive methods that can be used during sexual intercourse (<xref ref-type="bibr" rid="ref2">2</xref>). The literature includes studies that analyze the factors associated with the choice of contraceptive in relation to the sexual life of women. These studies highlight variables such as the subjective characteristics of the woman, and the availability and ease of use of the method (<xref ref-type="bibr" rid="ref3">3</xref>&#x2013;<xref ref-type="bibr" rid="ref5">5</xref>).</p>
<p>In addition, the cost associated with unwanted pregnancies is high. The majority of unintended pregnancies (26%) occur in women aged 30&#x2013;34&#x2009;years, while an estimated 69% of the total cost burden is attributable to poor adherence to contraceptive methods, with such a cause most likely being avoidable with the intervention of a health professional (<xref ref-type="bibr" rid="ref6">6</xref>).</p>
<p>Adequate identification of the sexual acceptability of contraceptive methods is key for designing health promotion interventions, assessing their impacts, and increasing their effectiveness. Currently, there are almost no standard instruments in the scientific literature to assess the sexual acceptability of contraceptive methods. Although one tool has been published recently to measure how the contraceptive method affects women&#x2019;s sexuality, this cannot be used as a means of matching the contraceptive method with women&#x2019;s sexual preferences (<xref ref-type="bibr" rid="ref7">7</xref>). Thus, there is a need for instruments that can be used in any context to determine which contraceptive method is preferred by women according to various factors, including their relationships.</p>
<p>This study aimed to develop and validate a Sexual acceptability of Contraceptive Methods questionnaire to explore women&#x2019;s preferences according to their epidemiological characteristics and their partner relationships. This instrument is called the <italic>Sexual Acceptability of Contraceptive Methods Questionnaire</italic> [in Spanish, Aceptabilidad Sexual de los M&#x00E9;todos Anticonceptivos (ASMA)].</p>
</sec>
<sec sec-type="methods" id="sec6">
<title>Methods</title>
<p>The study methodology included questionnaire development and validation.</p>
<sec id="sec7">
<title>Development stage</title>
<p>The development of the tool began with a conceptualization phase and was followed by the design and pilot testing of the questionnaire.</p>
<sec id="sec8">
<title>Conceptualization</title>
<p>he questionnaire conceptualization and construct (dimension) definition were carried out considering the following: (1) the aim of the tool; (2) a bibliographic review on the topic using the CINAHL, PubMed, Psychinfo, and SciELO databases, combining the search terms &#x201C;(contraception OR contraceptive OR contraceptive device OR contraceptive devices) AND (pleasure OR libido OR &#x201C;sexual function&#x201D; OR &#x201C;sexual functioning&#x201D; OR sexuality NOT [&#x201C;sexual behavior&#x201D; OR &#x201C;sexual health&#x201D;]),&#x201D; and institutional web pages (e.g., World Health Organization); (3) a qualitative study with 6 experts on contraception and/or sexuality issues and content analysis; and (4) the research team&#x2019;s experience. The experts have been selected from among medical professionals with training in contraception and sexology and with research experience.</p>
</sec>
<sec id="sec9">
<title>Questionnaire design</title>
<p>The questionnaire was designed to include nominal scale items to collect sociodemographic/epidemiological information and Likert or nominal scales to assess each dimension. The item sequence was determined considering the construct criteria, order, and specificity. The questionnaire was edited for length and format.</p>
<p>Inclusion criteria were: Female between 16 and 50 years, currently having sex. Adequate command of oral and written Spanish and overt desire to use contraceptive measures. Data collection took place in gynecology consultations during a full year at the Hospital Cl&#x00ED;nico Universitario Lozano Blesa in Zaragoza (Spain).</p>
</sec>
<sec id="sec10">
<title>Pilot</title>
<p>To assess the acceptability and content validity of the questionnaire, the first draft (66 items, 28 sociodemographic/epidemiological and 38 sexual/contraceptive-related questions) was reviewed independently by seven key experts. A copy of the first draft of the questionnaire was sent to the experts via email. The purpose of this revision was to eliminate questions based on their relevance for achieving the objectives of the study (items that more than 70% of the experts believed to be unsuitable/irrelevant for the study were eliminated), and to modify the wording of some items to facilitate understanding by any person regardless of their cultural, social, and economic level.</p>
<p>Then, a second draft of the questionnaire (55 items: 28 sociodemographic/epidemiological and 27 sexual/contraceptive-related questions) was distributed to a convenience sample of 216 women. A descriptive analysis was then conducted to explore the frequency distributions and ceiling and roof effects (&#x003E;70% of the responses grouped under the extreme options) and reliability, using Cronbach&#x2019;s alpha to estimate internal consistency. In all instances, the participants were informed about the study by one of the researchers and were also provided with written information. In the initial stages, written consent was obtained from all participants.</p>
</sec>
<sec id="sec11">
<title>Psychometric validation stage</title>
<p>After the pilot study, a psychometric validation of the first version of the questionnaire (52 items: 28 sociodemographic/epidemiological and 24 sexual/contraceptive-related questions) was carried out (<xref rid="SM1" ref-type="supplementary-material">Supplementary Appendix 1</xref>).</p>
<p>Two recommendations were considered to estimate the sample size at this stage, that is, 8&#x2013;10 participants were needed for each item in the questionnaire and 192&#x2013;240 participants were required to obtain a &#x201C;very good&#x201D; sample for conducting factor analysis (<xref ref-type="bibr" rid="ref8">8</xref>); at least 216 were needed for EFA while a subsample of 83 participants were required to analyze test&#x2013;retest reliability.</p>
<p>The Doornik-Hansen test for normality analysis was conducted on the data collected, and a descriptive analysis was performed to explore each item&#x2019;s acceptability and to identify the ceiling and roof effects. Exploratory factor analysis (EFA) (<xref ref-type="bibr" rid="ref9">9</xref>, <xref ref-type="bibr" rid="ref10">10</xref>) and confirmatory factor analysis (CFA) were carried out in that order to explore the construct validity of the questionnaire (<xref ref-type="bibr" rid="ref11">11</xref>). Sampling adequacy was assessed using the Kaiser-Meyer-Olkin (KMO) test and the suitability of the data for factor analysis was confirmed using Bartlett&#x2019;s test of sphericity. Structural equation modeling (SEM) was applied, and the maximum likelihood method was used for estimation. The normed fit index (NFI), root mean square error of approximation (RMSEA), chi square test, and comparative fit index (CFI) were used to test the goodness-of-fit (<xref ref-type="bibr" rid="ref12">12</xref>). Correlations between the dimensions were explored through the Spearman correlation coefficient.</p>
<p>The reliability of the final version of the questionnaire was examined through Cronbach&#x2019;s alpha and McDonald omega for internal consistency.</p>
<p>All of the quantitative analyses were conducted using STATA statistical software (Stata Corp, College Station, Texas, United States).</p>
<p>This study was evaluated by the local ethics research committee (code: 22/2020). Written information about the study was provided to participants, and their consent to participate was assumed when they returned the completed questionnaire.</p>
</sec>
</sec>
</sec>
<sec sec-type="results" id="sec12">
<title>Results</title>
<sec id="sec13">
<title>Descriptive analysis</title>
<p><xref ref-type="table" rid="tab1">Table 1</xref> reports the sociodemographic characteristics of the 216 participants. The mean age was 33.98&#x2009;years (dt:7.74) with a BMI classified as normal weight. Of the sample, 21.30% had chronic diseases, while it is also worth mentioning that 15.74% had induced abortion.</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption><p>Sociodemographic characteristics of the sample.</p></caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variable</th>
<th align="center" valign="top" colspan="2">Frequency (percentage)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Age (Mean, SD)</td>
<td align="center" valign="top" colspan="2">33.98 (7.74)</td>
</tr>
<tr>
<td align="left" valign="top">IMC (Mean, SD)</td>
<td align="center" valign="top" colspan="2">24.46 (5.34)</td>
</tr>
<tr>
<td align="left" valign="top">Chronic disease</td>
<td align="center" valign="top" colspan="2">46 (21.30%)</td>
</tr>
<tr>
<td align="left" valign="top">Vaginal deliveries</td>
<td align="center" valign="top" colspan="2">136 (62.96%)</td>
</tr>
<tr>
<td align="left" valign="top">Number of deliveries</td>
<td align="center" valign="top" colspan="2">1.18 (1.26)</td>
</tr>
<tr>
<td align="left" valign="top">Cesarean</td>
<td align="center" valign="top" colspan="2">32 (14.81%)</td>
</tr>
<tr>
<td align="left" valign="top">Spontaneous abortions</td>
<td align="center" valign="top" colspan="2">26 (12.04%)</td>
</tr>
<tr>
<td align="left" valign="top">Induced abortions</td>
<td align="center" valign="top" colspan="2">34 (15.74%)</td>
</tr>
<tr>
<td align="left" valign="top">Gynecological history</td>
<td align="center" valign="top" colspan="2">30 (13.89%)</td>
</tr>
<tr>
<td align="left" valign="top">Chronic drugs</td>
<td align="center" valign="top" colspan="2">47 (21.76%)</td>
</tr>
<tr>
<td align="left" valign="top">Habitual intake of intoxicants</td>
<td align="center" valign="top" colspan="2">64 (29.63%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Personal socioeconomic level</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">No income</td>
<td align="center" valign="top">44 (20.37%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">0 to 12.450 (&#x20AC;)</td>
<td align="center" valign="top">95 (43.98%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">12.450 a 20.200 (&#x20AC;)</td>
<td align="center" valign="top">51 (23.61%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">20.200 a 35.200 (&#x20AC;)</td>
<td align="center" valign="top">22 (10.19%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">35.200 a 60.000 (&#x20AC;)</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">&#x003E;60.000 (&#x20AC;)</td>
<td align="center" valign="top">1 (0.46%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Family socioeconomic level</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">No income</td>
<td align="center" valign="top">4 (1.85%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">0 to 12.450 (&#x20AC;)</td>
<td align="center" valign="top">51 (23.61%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">12.450 a 20.200 (&#x20AC;)</td>
<td align="center" valign="top">74 (34.26%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">20.200 a 35.200 (&#x20AC;)</td>
<td align="center" valign="top">59 (27.31%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">35.200 a 60.000 (&#x20AC;)</td>
<td align="center" valign="top">24 (11.11%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">&#x003E;60.000 (&#x20AC;)</td>
<td align="center" valign="top">4 (1.85%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Employment status</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Self-employed</td>
<td align="center" valign="top">21 (9.72%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Employment as an employee</td>
<td align="center" valign="top">22 (10.19%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Unemployed</td>
<td align="center" valign="top">126 (58.33%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Unpaid household work</td>
<td align="center" valign="top">21 (9.72%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Student</td>
<td align="center" valign="top">25 (11.57%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Disabled</td>
<td align="center" valign="top">1 (0.46%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Education level</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">No studies</td>
<td align="center" valign="top">10 (4.63%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Primary studies</td>
<td align="center" valign="top">45 (20.83%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Secondary education</td>
<td align="center" valign="top">104 (48.15%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">University</td>
<td align="center" valign="top">57 (26.39%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Type of education according to financing</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Did not attend school</td>
<td align="center" valign="top">7 (3.24%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Public</td>
<td align="center" valign="top">153 (70.83%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Public/privately funded</td>
<td align="center" valign="top">55 (25.46%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Private</td>
<td align="center" valign="top">1 (0.46%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Type of school attended according to religious education</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Did not attend school</td>
<td align="center" valign="top">66 (30.56%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Lay</td>
<td align="center" valign="top">149 (68.98%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Religious</td>
<td align="center" valign="top">1 (0.46%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Religion</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Agnostic</td>
<td align="center" valign="top">19 (8.80%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Atheist</td>
<td align="center" valign="top">32 (14.81%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Muslim</td>
<td align="center" valign="top">14 (6.48%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Practicing Catholic</td>
<td align="center" valign="top">30 (13.89%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Non-practicing Catholic</td>
<td align="center" valign="top">84 (38.89%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Evangelist</td>
<td align="center" valign="top">13 (6.02%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Jehovah&#x2019;s witness</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Other</td>
<td align="center" valign="top">21 (9.72%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Origin/ethnicity</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">North American</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">South American</td>
<td align="center" valign="top">35 (16.20%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Spanish</td>
<td align="center" valign="top">131 (60.65%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">European</td>
<td align="center" valign="top">19 (8.80%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Eastern countries</td>
<td align="center" valign="top">8 (3.70%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Maghreb</td>
<td align="center" valign="top">10 (4.63%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Sub-Saharan African</td>
<td align="center" valign="top">7 (3.24%)</td>
</tr>
<tr>
<td/>
<td align="center" valign="top">Gypsy</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>Moreover, 43.98% of the women had an income below 12,450 euros, 34.26% between 12,450 and 20,200 and 27.31% more than 20,200. Regarding employment and education status, 58.33% were unemployed and 48.15% had a high school education, while 70.83% were educated in public schools and 68.98% secular schools.</p>
<p><xref ref-type="table" rid="tab2">Table 2</xref> describes the participants&#x2019; relationships and sexual preferences. Only 15.28% did not have a steady partner and 13.43% had a steady partner but did not live with them. Concerning the length of time in a couple relationship, 44.91% of the women had been co-habiting with their partner for more than 10&#x2009;years, while 9.17% had two current sexual partners and 19.91% had had more than one relationship at the same time. A total of 86.57% declared themselves heterosexual and 63.43% of the respondents had sex on a weekly basis.</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption><p>Description of the sexual relations and contraceptive methods used by the participants.</p></caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Variable</th>
<th align="center" valign="top" colspan="2">Frequency (percentage)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" colspan="3">Type of partner</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Living together as a couple</td>
<td align="center" valign="top">154 (71.29%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Steady partner not living together</td>
<td align="center" valign="top">29 (13.43%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No steady partner</td>
<td align="center" valign="top">33 (15.28%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Time with partner</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No steady partner</td>
<td align="center" valign="top">33 (15.28%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Less than 2&#x2009;years</td>
<td align="center" valign="top">24 (11.11%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">2&#x2013;5&#x2009;years</td>
<td align="center" valign="top">28 (12.96%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">5&#x2013;10&#x2009;years</td>
<td align="center" valign="top">34 (15.74%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E; 10&#x2009;years</td>
<td align="center" valign="top">97 (44.91%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Length of co-habitation</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No co-habitation</td>
<td align="center" valign="top">62 (28.70%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Less than 2&#x2009;years</td>
<td align="center" valign="top">22 (10.19%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">2&#x2013;5&#x2009;years</td>
<td align="center" valign="top">24 (11.11%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">5&#x2013;10&#x2009;years</td>
<td align="center" valign="top">27 (12.50%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E; 10&#x2009;years</td>
<td align="center" valign="top">81 (37.50%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Number of CURRENT sexual partners</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">0</td>
<td align="center" valign="top">11 (5.09%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">1</td>
<td align="center" valign="top">196 (90.74%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">2</td>
<td align="center" valign="top">9 (4.17%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Sexual relationships at the same time</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">173 (80.09%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">43 (19.91%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Caregivers in the home</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">0</td>
<td align="center" valign="top">71 (32.87%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">1</td>
<td align="center" valign="top">143 (66.20%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">2</td>
<td align="center" valign="top">2 (0.93%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Sexual orientation</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Homosexual</td>
<td align="center" valign="top">8 (3.70%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Bisexual</td>
<td align="center" valign="top">18 (8.33%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Heterosexual</td>
<td align="center" valign="top">187 (86.57%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Other</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Sexual activity</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Daily</td>
<td align="center" valign="top">17 (7.87%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Weekly</td>
<td align="center" valign="top">137 (63.43%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Monthly</td>
<td align="center" valign="top">29 (13.43%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Sporadic</td>
<td align="center" valign="top">33 (15.28%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Frequency of contraceptive use</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Always</td>
<td align="center" valign="top">134 (62.04%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Almost always</td>
<td align="center" valign="top">36 (16.67%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Sometimes</td>
<td align="center" valign="top">26 (12.04%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Never</td>
<td align="center" valign="top">20 (9.26%)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="3">Reason for change</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Problems with frequency of use</td>
<td align="center" valign="top">32 (14.81%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Adverse effects</td>
<td align="center" valign="top">40 (18.52%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Problems with sexual relations</td>
<td align="center" valign="top">38 (17.59%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Economic issues</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Effectiveness</td>
<td align="center" valign="top">48 (22.22%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Pregnancy during use</td>
<td align="center" valign="top">3 (1.39%)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Other</td>
<td align="center" valign="top">52 (24.07%)</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>With respect to contraceptive use, 9.26% never used contraceptives and only 12.04% used them occasionally. The most commonly used contraceptives were the classic combined pill and the gestagen-only pill, used by more than 50% of them. The reason for wanting to change contraceptive methods was the appearance of adverse effects, efficacy, and problems with sexual intercourse.</p>
<p>The sample size for the factor analysis consisted of the 24 sexual/contraceptive-related items. The Kaiser-Meyer-Olkin (KMO) value was 0.7873, considered adequate for the factor analysis, and the Bartlett&#x2019;s test of sphericity also demonstrated satisfactory suitability of the data for factor analysis (<italic>p</italic>&#x2009;&#x003C;&#x2009;0.001). A loading cutoff of &#x003E;1 was adopted, complying with Kaiser&#x2019;s rule, and three factors were extracted. This structure accounted for 71.50% of the model variance (see <xref ref-type="table" rid="tab3">Table 3</xref>).</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption><p>Exploratory factor analysis showing total variance explained with three factors.</p></caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Factor</th>
<th align="center" valign="top">Eigenvalue</th>
<th align="center" valign="top">Difference</th>
<th align="center" valign="top">% factor variance</th>
<th align="center" valign="top">% total variance</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Factor 1</td>
<td align="center" valign="top">1,2045</td>
<td align="center" valign="top">0.17395</td>
<td align="center" valign="top">0.2832</td>
<td align="center" valign="top">0.2832</td>
</tr>
<tr>
<td align="left" valign="top">Factor 2</td>
<td align="center" valign="top">1,0305</td>
<td align="center" valign="top">0.22494</td>
<td align="center" valign="top">0.2423</td>
<td align="center" valign="top">0.5255</td>
</tr>
<tr>
<td align="left" valign="top">Factor 3</td>
<td align="center" valign="top">1,0112</td>
<td align="center" valign="top">0.01935</td>
<td align="center" valign="top">0.1894</td>
<td align="center" valign="top">0.7150</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>The three-factor structure of the model is described in <xref ref-type="table" rid="tab4">Table 4</xref>, where three conceptual dimensions were identified. Factor 1 (explaining 28.32% of the model) corresponds to questions related to the use and placement of the contraceptive method and includes 6 items; Factor 2 (explaining 24.23%) corresponds to other factors that affect the relationship such as bleeding and side effects of the contraceptive method and includes 10 items; and Factor 3 (explaining 18.94%) corresponds to the couple relationship and includes 8 items.</p>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption><p>Exploratory factor analysis results for the ASMA questionnaire.</p></caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Item</th>
<th align="center" valign="top">Factor 1</th>
<th align="center" valign="top">Factor 2</th>
<th align="center" valign="top">Factor 3</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">p1</td>
<td/>
<td/>
<td align="center" valign="top">0.3803</td>
</tr>
<tr>
<td align="left" valign="top">p2</td>
<td/>
<td/>
<td align="center" valign="top">0.4251</td>
</tr>
<tr>
<td align="left" valign="top">p3</td>
<td/>
<td/>
<td align="center" valign="top">0.4833</td>
</tr>
<tr>
<td align="left" valign="top">p4</td>
<td/>
<td/>
<td align="center" valign="top">0.2099</td>
</tr>
<tr>
<td align="left" valign="top">p5</td>
<td/>
<td/>
<td align="center" valign="top">0.2805</td>
</tr>
<tr>
<td align="left" valign="top">p6</td>
<td/>
<td/>
<td align="center" valign="top">0.2112</td>
</tr>
<tr>
<td align="left" valign="top">p7</td>
<td align="center" valign="top">0.3627</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">p8</td>
<td align="center" valign="top">0.3185</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">p9</td>
<td align="center" valign="top">0.2365</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">p10</td>
<td align="center" valign="top">0.3385</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">p11</td>
<td align="center" valign="top">0.3548</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">p12</td>
<td align="center" valign="top">0.3412</td>
<td/>
<td/>
</tr>
<tr>
<td align="left" valign="top">p13</td>
<td/>
<td align="center" valign="top">0.3989</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p14</td>
<td/>
<td align="center" valign="top">0.3245</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p15</td>
<td/>
<td align="center" valign="top">0.2186</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p16</td>
<td/>
<td align="center" valign="top">0.2218</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p17</td>
<td/>
<td/>
<td align="center" valign="top">0.2253</td>
</tr>
<tr>
<td align="left" valign="top">p18</td>
<td/>
<td align="center" valign="top">0.2728</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p19</td>
<td/>
<td align="center" valign="top">0.3243</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p20</td>
<td/>
<td align="center" valign="top">0.2177</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p21</td>
<td/>
<td align="center" valign="top">0.3379</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p22</td>
<td/>
<td align="center" valign="top">0.2140</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p23</td>
<td/>
<td align="center" valign="top">0.3661</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">p24</td>
<td/>
<td/>
<td align="center" valign="top">0.2611</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>To analyze the internal consistency or homogeneity of the instrument, Cronbach&#x2019;s alpha and McDonald omega were used for each of the dimensions obtained in the AF. <xref ref-type="table" rid="tab5">Table 5</xref> shows the values obtained, where we can observe high values close to unity, indicating that each of the factors yielded by the factor analysis is consistent in the sense that its constituent items are stable in this dimension.</p>
<table-wrap position="float" id="tab5">
<label>Table 5</label>
<caption><p>Cronbach&#x2019;s alpha and McDonald&#x2019;s omega for factors and total questionnaire.</p></caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Factor</th>
<th align="center" valign="top">Cronbach&#x2019;s alpha</th>
<th align="center" valign="top">McDonald&#x2019;s omega</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Factor 1</td>
<td align="center" valign="top">0.8388</td>
<td align="center" valign="top">0.8048</td>
</tr>
<tr>
<td align="left" valign="top">Factor 2</td>
<td align="center" valign="top">0.7501</td>
<td align="center" valign="top">0.7440</td>
</tr>
<tr>
<td align="left" valign="top">Factor 3</td>
<td align="center" valign="top">0.6631</td>
<td align="center" valign="top">0.6157</td>
</tr>
<tr>
<td align="left" valign="top">Total</td>
<td align="center" valign="top">0.7038</td>
<td align="center" valign="top">0.7017</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>Following the EFA, CFA was conducted, revealing a good fit to the model (NFI&#x2009;=&#x2009;0,741; RMSEA&#x2009;=&#x2009;0.048; CFI&#x2009;=&#x2009;0.779), which indicated that the theoretical three-factor structure of this model was adequate.</p>
</sec>
</sec>
<sec sec-type="discussion" id="sec14">
<title>Discussion</title>
<p>This is one of the first studies to develop and validate a tool to assess the sexual acceptability of contraceptive methods. The ASMA questionnaire evaluates the acceptability of contraceptive methods considering epidemiological factors as well as lifestyle, socioemotional aspects, educational level, and religious beliefs.</p>
<p>Until now, the scientific literature has only presented a single questionnaire for studying the Contraceptive Sexual Acceptability (CSA scale) (<xref ref-type="bibr" rid="ref7">7</xref>). These authors developed a tool based on the conceptual model of the sexual acceptability of contraception (<xref ref-type="bibr" rid="ref5">5</xref>, <xref ref-type="bibr" rid="ref13">13</xref>, <xref ref-type="bibr" rid="ref14">14</xref>). This recent scale provides a measure that asks women to rate their satisfaction with physical (including sexual functioning, quality, frequency of orgasm, and arousal), psychological (emotional openness or capacity for surrender) and interpersonal domains. The CSA scale was created to identify the acceptability of contraceptives and to measure the changes in sexuality that users attribute to a new contraceptive method. This scale is based on classic questionnaires in the literature (FSFI, NSSS), which evaluate the various aspects of female sexual response during the use of contraceptive methods. In this regard, the ASMA scale can be used in women seeking contraception, allowing the clinician to recommend the most suitable method according to the woman&#x2019;s sexual preferences and particularities.</p>
<p>Caruso et al. (<xref ref-type="bibr" rid="ref15">15</xref>) analyzed the impact of hormonal contraception on women&#x2019;s sexuality, focusing on aspects such as their components, route, and regimen (<xref ref-type="bibr" rid="ref15">15</xref>). In this regard, the ASMA questionnaire was created to identify key elements of the contraceptive sexual acceptability construct. Another novel aspect of our questionnaire instrument compared with that described by Caruso et al. (<xref ref-type="bibr" rid="ref15">15</xref>) is that the ASMA questionnaire seeks to evaluate women&#x2019;s preferences according to epidemiological characteristics, where we include age and sexual orientation and type of partner relationship, along with socioeconomic, educational, and religious factors.</p>
<p>The central aim of the ASMA questionnaire was to identify profiles of factors associated with the different types of contraceptives. Therefore, this instrument is the first to comprehensively assess women&#x2019;s contraceptive needs with the aim of achieving full satisfaction in their sexual relationships.</p>
<p>All of the items included in the scale are critical for evaluating the sexual acceptability of contraceptives. The questionnaire begins with demographic and clinical questions about the woman&#x2019;s medical history that may affect her sexual relations or preference for a particular type of contraceptive. This is followed by personal and family economic questions, as well as the type of relationship and cohabitation with the partner. All these questions are of great relevance for establishing a woman&#x2019;s profile for a given type of contraceptive method. In refining this part of the scale, statistically informed decisions were made based on the results of the analysis. The second part of the scale consists of questions related to the reality of their sexual lives, enquiring about aspects that can be influenced by the various contraceptive methods. The responses can then be used as a basis for providing contraceptive counseling.</p>
<p>Although the questionnaire is a helpful tool for contraceptive counseling and prescription, we must always bear in mind that during the consultation the user might also communicate other individual variables not reflected in the questionnaire, and such information could also be decisive in the choice of contraceptive method.</p>
<p>The internal theoretical structure of the initial questionnaire was slightly modified, maintaining 3 factors but slightly changing the way of grouping the items.</p>
<p>However, all these constructs are theoretically consistent and present good internal consistency and reliability. In future studies, it will be useful to explore the correlations between factors.</p>
<sec id="sec15">
<title>Limitations and strengths</title>
<p>The lack of similar instruments for assessing the acceptability of contraceptive methods did not allow us to assess criterion validity against a &#x201C;gold standard&#x201D; (<xref ref-type="bibr" rid="ref9">9</xref>). However, having a frame of reference defined by health professionals for the subject under analysis along with a content and appearance validation of the questionnaire conducted by experts is one of the strengths in the design of this preliminary instrument. Although psychometric validation analysis revealed that the ASMA questionnaire is valid and reliable, additional validations in different populations could contribute to its improvement (10). Given that a high percentage of the sample were non-Spanish women, the results of the analysis suggest good cultural adaptability.</p>
</sec>
<sec id="sec16">
<title>Future usefulness of the tool</title>
<p>The developed instrument could help health professionals in routine clinical practice to identify the best contraceptive method for a woman who attends the clinic seeking information and help in this regard, identifying the method that best suits the profile of each individual.</p>
<p>In conclusion, the ASMA questionnaire is a valid and reliable tool for assessing the sexual acceptability of various contraceptive methods. The ASMA questionnaire collects data and provides information on different factors concerning women&#x2019;s sexuality, health, education, and beliefs &#x2014; factors that can determine the preference for one contraceptive method over another. It can thus be used to identify profiles of women with different preferences, helping them to choose the most suitable method.</p>
</sec>
</sec>
<sec sec-type="data-availability" id="sec17">
<title>Data availability statement</title>
<p>The datasets presented in this article are not readily available because of data protection law. Requests to access the datasets should be directed to <email>isalahoz@yahoo.com</email>.</p>
</sec>
<sec sec-type="ethics-statement" id="sec18">
<title>Ethics statement</title>
<p>Written informed consent to participate in this study was provided by the participants. The studies involving human participants were reviewed and approved by the Aragon Research Ethics Committee-CEICA with protocol number PI20/488.</p>
</sec>
<sec sec-type="author-contributions" id="sec19">
<title>Author contributions</title>
<p>IL-P: Conceptualization, Investigation, Software, Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing. AJ-L: Data curation, Methodology, Supervision, Writing &#x2013; original draft. RJ-V: Funding acquisition, Resources, Visualization, Writing &#x2013; original draft. IS-A: Funding acquisition, Resources, Visualization, Writing &#x2013; original draft. RR: Funding acquisition, Resources, Visualization, Writing &#x2013; original draft. SR-L: Formal analysis, Project administration, Writing &#x2013; original draft. ST: Methodology, Project administration, Supervision, Validation, Writing &#x2013; original draft. MD-V: Data curation, Formal analysis, Investigation, Software, Writing &#x2013; original draft. AL-M: Investigation, Methodology, Resources, Writing &#x2013; original draft. NM-L: Conceptualization, Formal analysis, Methodology, Supervision, Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing.</p>
</sec>
</body>
<back>
<sec sec-type="funding-information" id="sec20">
<title>Funding</title>
<p>The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.</p>
</sec>
<ack>
<p>We would like to thank the contraceptive users who voluntarily took part in this study that is part of my doctoral thesis, and to Health Care Centre Inocencio Jimenez nurse, Elena Ari&#x00F1;o, for her unconditional help in all my projects. &#x201C;<italic>Your English Lab</italic>&#x201D; has reviewed the language and style of this article.</p>
</ack>
<sec sec-type="COI-statement" id="sec21">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="sec100" sec-type="disclaimer">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="sec22">
<title>Supplementary material</title>
<p>The Supplementary material for this article can be found online at: <ext-link xlink:href="https://www.frontiersin.org/articles/10.3389/fpubh.2023.1302675/full#supplementary-material" ext-link-type="uri">https://www.frontiersin.org/articles/10.3389/fpubh.2023.1302675/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Table_1.DOCX" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
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