Cross-border mobility in the Meuse-Rhine Euroregion: impact of COVID-19 border restrictions on everyday activities and visiting social network members

Introduction Cross-border mobility (CBM) to visit social network members or for everyday activities is an important part of daily life for citizens in border regions, including the Meuse-Rhine Euroregion (EMR: neighboring regions from the Netherlands, Belgium, and Germany). We assessed changes in CBM during the COVID-19 pandemic and how participants experienced border restrictions. Methods Impact of COVID-19 on the EMR’ is a longitudinal study using comparative cross-border data collection. In 2021, a random sample of the EMR-population was invited for participation in online surveys to assess current and pre-pandemic CBM. Changes in CBM, experience of border restrictions, and associated factors were analyzed using multinomial and multivariable logistic regression analysis. Results Pre-pandemic, 82% of all 3,543 participants reported any CBM: 31% for social contacts and 79% for everyday activities. Among these, 26% decreased social CBM and 35% decreased CBM for everyday activities by autumn 2021. Negative experience of border restrictions was reported by 45% of participants with pre-pandemic CBM, and was higher (p < 0.05) in Dutch participants (compared to Belgian; aOR= 1.4), cross-border [work] commuters (aOR= 2.2), participants with cross-border social networks of friends, family or acquaintances (aOR= 1.3), and those finding the measures ‘limit group size’ (aOR= 1.5) and ‘minimalize travel’ (aOR= 2.0) difficult to adhere to and finding ‘minimalize travel’ (aOR= 1.6) useless. Discussion CBM for social contacts and everyday activities was substantial in EMR-citizens, but decreased during the pandemic. Border restrictions were valued as negative by a considerable portion of EMR-citizens, especially when having family or friends across the border. When designing future pandemic control strategies, policy makers should account for the negative impact of CBM restrictions on their citizens.


Introduction
The European Union (EU) comprises 360 internal land border regions, encompassing 40% of the territory and 38% of the EU population (1,2).Until March 2020, there was complete border permeability among the signatories of the Schengen Agreement (3).The coronavirus disease 2019 (COVID- 19) pandemic, which started in 2020, presented an unprecedented situation.The temporary reintroduction of border control resulted in a sudden restriction of free movement in the EU and had far-reaching health, social, and economic consequences (3).This situation also affected the border region Meuse-Rhine Euroregion (EMR), covering the border area of the Netherlands, Belgium, and Germany.
Mobility in the EMR is synonymous with cross-border mobility (CBM) due to the population living in close proximity to a national border.Mobility is crucial for accessing facilities and engaging in social interactions, and thereby various aspects of wellbeing and health.For example, in the EMR, CBM encompasses essential medical activities such as visiting healthcare professionals.Within the EMR there is a high degree of patient mobility and citizens tend to be highly willing to travel to neighboring member states to receive medical treatments (4).Border control measures during the pandemic hindered cross-border healthcare, resulting in challenges in cross-border communication and collaboration among EMR public health professionals (5).
Furthermore, CBM has various transport modes.Those that require physical activity, such as walking and cycling, have been shown to positively impact self-perceived health, mental health including perceived stress, loneliness, social health, and reduced mortality (6,7).Additionally, car use and use of public transportation have been associated with health outcomes such as increased physical activity, reduced social frailty in elderly, and reduced loneliness in European adults (6,8,9).Limited mobility during the COVID-19 pandemic has been linked to reduced happiness, also referred to as subjective wellbeing (10,11).Finally, mobility is associated with increased social participation (12).Maintaining CBM is thus important in health.
With a population of 4 million, the inhabitants of the EMR have extensive cross-border connections, including social contacts, work, study, leisure, and healthcare (3,5,(13)(14)(15)(16).Therefore, CBM is an important part of daily life for EMR-citizens and borders are generally perceived as non-existent (17).Citizens cross borders for several reasons which are interconnected, such as cross-border commuting, social visits, and leisure activities (18).This includes everyday activities such as grocery shopping and visiting restaurants, and in-person contact with social network members with visits to family, friends, and acquaintances living across the border (social visits).Social connections plays a crucial role in promoting physical and mental well-being, including happiness (19,20).Social isolation is associated with health risks, chronic illness, and all-cause mortality (21,22).Social networks can serve as a buffer by providing social support during stressful events, including the COVID-19 pandemic (23).However, social interactions have been shown to be significantly decreased during the pandemic, with fewer in-person contacts and reduced social network interactions (23).
The efficacy of border restrictions in controlling the transmission of SARS-CoV-2 has been debated.The effectiveness of border restrictions depends highly on timing, the stage of the epidemic, interconnectedness of countries, local measures undertaken, extent of implementation, and adherence (24,25).A study among 10,0001 citizens in the Dutch EMR subregion indicated that CBM was not associated with seroprevalence of SARS-CoV-2, which may suggest a limited role of border traffic in the virus spread (16).
By our knowledge, there are no existing reports on CBM for visiting social network members and everyday activities in the EMR.Whilst it is known that CBM decreased during the pandemic (15), it is not clear to which extent, and how citizens experienced CBM restrictions.
This study aimed to assess changes in cross-border visits during the pandemic and the impact of border restrictions on citizens in the EMR, focusing on differences between the three regions.Therefore, we assessed factors associated with changes in CBM for social contacts and everyday activities in autumn of 2021, compared to before the COVID-19 pandemic, and which factors are associated with experienced negative impact of border restrictions.

Methods
Context of border restrictions in the EMR during the COVID-19 pandemic survey was conducted in EMR-subregions, including the Belgian provinces Limburg (Dutch-speaking), Liège (French-speaking), and the German-speaking community of Belgium (Ostbelgien as a part of Liège).Apart from that, South Limburg (the Netherlands; Dutchspeaking) and the German City of Aachen and Districts of Düren and Heinsberg (German-speaking) were included (Figure 2).
Participants were recruited through written invitations, including a letter and questionnaire link, based on national resident registers.In spring 2021, a random sample of in total 26,925 citizens aged 18 years and older, residing in private households in the EMR, was selected from the national registers in each country and invited to participate.Further details about the sampling methods applied in each country, stepwise selection, and opt-out procedures has been described previously (27).Participation rates ranged from 15.3% in the Belgian subregions (8,911 invitees and 1,366 participants) to 27% (11,266 invitees and 3,042 participants) and 26.7% (6,748 invitees and 1,598 participants) in the Dutch and German subregions, respectively.All 6,006 initial participants (round one) were subsequently invited for follow-up (round two).
Questionnaire data on CBM were collected between April 13 and June 29, 2021 (round one) and between September 21 and November 20, 2021 (round two; Figure 1).
A total of 3,557 participants completed the questionnaires from both rounds.In the current study, CBM behavior and impact of border restrictions are described for the 3,543 participants who had no missing data for variables included in the analysis.

Measurements CBM pre-pandemic (outcome 1)
Participants reported whether they have family, friends or acquaintances in another EMR-country and how many times per month on average they crossed the border to either visit social network members or for everyday activities before the pandemic.Based on the distribution of the data, the number of total cross-border visits before the pandemic was grouped into 0 times per month, 1-2 times per month, 3-5 times per month, and ≥ 6 times per month.
We distinguished between different types of CBM: • Cross-border visits for visiting social network members: this was the average (as reported by the participant) number of times a month participants visited family, friends or acquaintances living across the border before the pandemic (measured in round one) and in the last month (round two).• Cross-border visits for everyday activities: this was the average (as reported by the participant) number of times a month a participant had crossed the border for a short visit (for example grocery shopping or visiting a restaurant), before the COVID-19 pandemic, i.e., before February 2020 (measured in round one) and in the last month (when filling in the round 2 questionnaire in September to November 2021).• Total visits were assessed by combining information on crossborder visits for social contacts or everyday activities.
Work-related CBM was not included as an outcome since changes herein were not evaluated and the number of participants working across the border was low.

Changes in CBM during the pandemic (outcome 2)
For CBM for social contacts (outcome 2a), everyday activities (outcome 2b), and total visits (outcome 2), participants were categorized into three groups based on their reported number of cross-border visits per month in autumn 2021 compared to before the COVID-19 pandemic: those with a decrease of more than one, those with an increase of more than one, and those with no change (a change of one or zero).

Experience of border restrictions (outcome 3)
Experienced impact of border restrictions was assessed by a question on whether the experience of border restrictions during the pandemic was negative for the participant themselves (five-point scale; from totally disagree to totally agree).For analyses, this outcome was grouped into 'neutral/no negative experience' (answers: neutral, disagree or totally disagree) and 'negative experience' (answers: totally agree or agree).

CBM and happiness (sub analysis)
Given that mobility and wellbeing are closely linked, we conducted a sub analysis to explore potential associations between happiness and cross-border visits.Data on happiness (' All things considered, how happy would you say you are?'), measured on a scale from 0 (unhappy) to 10 (happy), were collected for the pre-pandemic time point (assessed retrospectively in spring 2021) and in autumn 2021.A score < 8 was classified as indicative of unhappiness.

Covariates
Various socio-demographic factors were included: country (the Netherlands, Belgium or Germany), sex (male or female), age group (18-29, 30-39, 40-49, 50-59, 60-69 or ≥ 70 years), and level of education (theoretical or practical).Employment status was categorized into working in own country, working in another country, and not working.Apart from that, presence of comorbidities (yes/no) and having family, friends or acquaintances across the border (yes/no) were assessed.
Several measures that were taken in response to the COVID-19 pandemic were included in the questionnaire, such as 'limit group size' , 'minimalize travel' , and 'work from home' .We assessed perceived usefulness and perceived difficulty of these measures as measured in round one (at time when the measures were implemented).For perceived usefulness of measures, options were '(very) useful or neutral' and 'not useful (at all)' .Perceived difficulty was divided into '(very) easy or neutral' and '(very) difficult' .

Analytical approach and methodology
Data on CBM were measured for three different countries with seven different regions.In analyses, the focus was on countries (not regions) due to the low number of participants in some regions.In all analyses, we evaluated CBM for social contacts, everyday activities, and total visits.

CBM pre-pandemic (outcome 1)
CBM for total visits, visiting social network members, and for everyday activities was described.Subsequently, we described the characteristics of participants who had CBM for social visits or everyday activities compared to those who did not have CBM before the pandemic.Characteristics of participants with or without CBM before the pandemic were described in a table of N and proportions.Univariate and multivariable logistic regression analyses were used to determine whether differences between country of residence and other covariates were statistically significant.
Subsequently, we restricted further analyses to those participants who reported CBM pre-pandemic.

Changes in CBM during the pandemic (outcome 2)
Changes in total CBM, social CBM (outcome 2a), and CBM for everyday activities (outcome 2b) were examined using descriptive analyses.
To determine factors associated with changes in total CBM since baseline (decrease, increase or no change [+/− 1]), univariate and multivariable multinomial regression analyses were used.The main determinant was country.Covariates evaluated were the number of cross-border visits pre-pandemic, sex, age group, level of education, work situation, presence of comorbidities, having family, friends or acquaintances across the border, and perceived usefulness and perceived efficacy for the measures 'limit group size' , 'minimalize travel' , and 'work from home' .
Changes in CBM and associated factors was assessed for social visits (outcome 2a) and visits for everyday activities (outcome 2b) separately, restricted to the subpopulations who those who reported pre-pandemic social CBM or CBM for everyday activities.For these two outcomes, the number of pre-pandemic cross-border visits was included as a continuous variable, since participant numbers were smaller.

Experience of border restrictions (outcome 3)
To examine experience of border restrictions, univariate and multivariable logistic regression analyses were performed.Main determinants were country and changes in CBM (also defined as outcome 2).Other factors included were the number cross-border visits pre-pandemic, sex, age group, level of education, work situation, presence of comorbidities, having family, friends or acquaintances across the border, and perceived usefulness and perceived efficacy for the measures 'limit group size' , 'minimalize travel' , and 'work from home' .

CBM and happiness (sub analysis)
We used descriptive statistics, chi-square tests, and logistic regression analysis to assess the proportions of participants classified as unhappy, comparing different groups based on the average number of cross-border visits per month (0 [reference], 1 to 2, 3 to 5, or > 5).We performed univariate analysis, followed by adjusted analysis taking into account country, age, sex, and having social contacts across the border.

Statistical procedures and model building
For all main outcomes, univariate and multivariable models were adjusted for country and number of pre-pandemic crossborder visits.Apart from that, we corrected for changes in CBM for outcome 3.There was no multicollinearity between the included variables since Variance Inflation Factor (VIF) values were < 3.For pre-pandemic CBM, interactions between country and sex, as well as country and age, were tested and showed no statistically significant interaction.For model building, variables with a p-value of <0.10 in the univariate analysis were included in the multivariable models by backwards selection.A p-value of <0.05 was considered statistically significant to be retained in the final models.Data were analyzed with IBM Statistical Package for the Social Sciences (SPSS) version 27.

Study population
A total of 3,543 participants completed both questionnaires and had no missing data for the variables included in the analysis.Participants were on average 55 ± 15.5 years old and 59% was female.The majority of included participants was Dutch (N = 1791; 51%), followed by German (N = 1,030; 29%), and Belgian (N = 722; 20%).

Pre-pandemic CBM (outcome 1)
Of all 3,543 participants, 82% reported pre-pandemic CBM: 31% had at least one visit per month to cross-border social network members and 79% for everyday activities (Table 1).Differences in pre-pandemic CBM between the three countries were statistically significant in adjusted models (Supplementary Table 1).CBM was highest in the Netherlands (90% of participants; aOR = 4.4; 95%CI: 3.5-5.5),followed by Germany (81% of participants; aOR = 2.4; 95%CI 1.9-3.0),and Belgium (63% of participants; reference).CBM was >75% for all age groups.Participants who were employed more often reported CBM, with the highest proportion (96%) among participants working in another country.Most participants with pre-pandemic CBM had 1-2 cross-border visits per month (Table 1).
A decrease in cross-border visits (assessed at round 2) was observed in 40% of participants with pre-pandemic CBM, whereas 49% had no change or a change of one, and 11% had an increase of more than one (Table 2).The majority of participants (>90%) had a change between 2 and 5.

Factors associated with changes in CBM (outcome 2)
Around 40% of participants from the Netherlands and Germany experienced a decrease in CBM, compared to 32% in Belgium.Dutch participants most often had an increase in CBM (13%), followed by Belgian (8%) and German (9%) participants (Table 2).

Factors associated with changes in CBM to visit social network members (outcome 2a)
Participants in the Netherlands and Germany presented similar proportions of around 25% for a decrease in social CBM in autumn 2021, compared to pre-pandemic.Those with a decrease of >1 in social CBM had an average number of pre-pandemic border crossings of 12.46, whereas it was 10.09 for those with an increase.This was the only factor associated with a decrease in social CBM between autumn 2021 and baseline (aOR = 1.2; 95%CI 1.1-1.2).Factors independently associated with an increase of >1 in cross-border visits were working across the border (aOR = 4.1; 95%CI 1.6-10.4),low perceived usefulness of 'minimalize travel' (aOR = 2.1; 95%CI 1.1-3.8)and a higher number of pre-pandemic border crossings per month (aOR = 1.1; 95%CI 1.1-1.2;Table 3).

Factors associated with changes in CBM for everyday activities (outcome 2b)
In autumn 2021, around 35% of Dutch and German participants and 28% of Belgian participants showed a decrease in CBM for everyday activities, compared to pre-pandemic.Dutch participants most often had an increase in CBM (11%; Table 4).

Outcome 3: experienced negative impact of border restrictions
Out of the 2,900 participants with pre-pandemic CBM, 1299 (45%) reported having experienced the border restrictions during the pandemic as negatively for themselves (Table 5).

CBM and happiness
Pre-pandemic, 28% of participants with no CBM were classified as unhappy, compared to 17% of participants with >5 cross-border visits per month.In autumn 2021, proportions of unhappiness ranged between 33 and 36% for participants with CBM, and was 41% for participants with no CBM (Figure 4).

Summary
This study examined changes in CBM and the impact of border restrictions in the EMR during the COVID-19 pandemic.Pre-pandemic, CBM was frequent, reported by 82%, with the highest proportion reported among Dutch participants.In autumn 2021, 40% of participants with pre-pandemic CBM, had decreased their number of cross-border visits (35% reduced CBM for everyday activities and 26% for visiting social contacts), while 49% had no change or a minor change, and 11% had an increase.A negative experienced impact of border restrictions was reported by 45% of participants who had pre-pandemic CBM.Negative experience was associated with Dutch residency, working across the border, having social contacts across the border, and finding measures useless or difficult to adhere to.CBM was associated with being happy, both pre-pandemic and during the pandemic, in autumn 2021.

Pre-pandemic CBM and changes in CBM
This study provides unique insights as it is the first to investigate changes in CBM for visiting social network members and everyday activities in the EMR.Pre-pandemic, CBM was high (82%) among participants, with some variation in the three countries, with the   The parts of the Meuse-Rhine Euroregion (EMR) included in this study.Reference = no change in long cross-border visits for visiting social network members.OR, odds ratio; 95%CI = 95% confidence interval.Nagelkerke pseudo-R 2 value of the multivariable model = 0.24.Decrease > 1 indicates a decrease of 1 or more long cross-border visits to visit family, friends or acquaintances per month in autumn 2021, compared to before the COVID-19 pandemic.Increase > 1 indicates an increase of 1 or more long cross-border visits to visit family, friends or acquaintances per month in autumn 2021, compared to before the COVID-19 pandemic.R1 = round 1 questionnaire.A For 'work from home' , all participants who were not working (e.g., retired, students) were grouped 'not applicable' .This group was then included in the categories of '(very) useful or neutral' for perceived usefulness, and '(very) easy or neutral' for perceived efficacy of working from home.Reference = no change in short cross-border visits for everyday activities.OR, odds ratio; 95%CI = 95% confidence interval.Nagelkerke pseudo-R 2 value of the multivariable model = 0.29.Decrease > 1 indicates a decrease of 1 or more short cross-border visits for everyday activities (e.g., grocery shopping, visiting restaurants) per month in autumn 2021, compared to before the COVID-19 pandemic.Increase > 1 indicates an increase of 1 or more short cross-border visits for everyday activities (e.g., grocery shopping, visiting restaurants) per month in autumn 2021, compared to before the COVID-19 pandemic.R1, round 1 questionnaire.A For 'work from home' , all participants who were not working (e.g., retired, students) were grouped 'not applicable' .This group was then included in the categories of '(very) useful or neutral' for perceived usefulness, and '(very) easy or neutral' for perceived efficacy of working from home.A substantial proportion of participants decreased their number of cross-border visits during the pandemic.Prior research in 25 country pairs using phone and Facebook similarly demonstrated a sharp decline in CBM of up to 82% compared to pre-pandemic levels (28).Compared to Belgium and German participants, Dutch participants more frequently showed an increase in both overall visits and short visits, adjusted for other characteristics.A previous study showed that Dutch citizens were less likely to restrict CBM for everyday activities or social contacts, compared to Belgian citizens (29).This can pose challenges for implementing policies, as cultural differences impact people's responses to measures in different places.It was suggested that culture can influence pandemic-related behaviors, even apart from individual beliefs (29).To demonstrate, we previously showed that in the EMR, compliance and evaluation of COVID-19 measures, as well as intention to take the COVID-19 booster vaccine, were highest among German citizens and lower among Dutch citizens (30,31).
Expectedly, finding travel-related measures difficult to adhere to or useless was associated with the CBM outcomes in the present study.Previous research has also linked beliefs on policies' effectiveness to a greater likelihood of engaging in the associated behaviors (29).Other factors such as (health) literacy and communication of measures are also associated with compliance (32).
Despite the absence of CBM restrictions in autumn 2021, CBM remained lower compared to the pre-pandemic period, suggesting the presence of longer-lasting effects and structural changes in citizens' mobility behavior.These changes likely resulted from the necessary adaptations in routines during the pandemic when work, school, family situations, and social interactions were disrupted (33).

Impact of border restrictions
Overall, a significant portion of participants (45%) reported a negative experienced impact of border restrictions, with the highest proportion among Dutch participants.Approaches to border restrictions varied per country, with Belgium physically closing its borders, Germany implementing border checks, and the Netherlands only discouraging CBM.CBM has been linked to wellbeing and happiness, in line with findings of the current study.Previous research has shown links between free movement and experienced health, as daily mobility and spatial behavior can influence individuals' wellbeing and happiness (10, 33).Negative experiences with border restrictions have been associated with worse mental health outcomes in Australia (34).Additionally, a report on 20 case studies conducted in several European border regions indicated that border restrictions had a negative impact on residents' personal lives as families living on both sides of the border were divided (15).EMR-residents also faced challenges in accessing up-to-date country-specific information and keeping track of constantly changing rules, highlighting a need for improved communication and access to information (16,17).
Having social contacts (friends or family) across the border was a crucial independent factor associated with a negative experience with border restrictions.It has been argued that the social isolation Reference = no negative experience of border restrictions.OR, odds ratio; 95%CI = 95% confidence interval.Nagelkerke pseudo-R 2 value of the multivariable model = 0.17.Decrease > 1 indicates a decrease of 1 or more cross-border visits per month in autumn 2021, compared to before the COVID-19 pandemic.Increase > 1 indicates an increase of 1 or more cross-border visits per month in autumn 2021, compared to before the COVID-19 pandemic.R1, round 1 questionnaire.A For 'work from home' , all participants who were not working (e.g., retired, students) were grouped 'not applicable' .This group was then included in the categories of '(very) useful or neutral' for perceived usefulness, and '(very) easy or neutral' for perceived efficacy of working from home.

Implications
Fostering social contact, such as by maintaining mobility, is not usually included in public health policy or pandemic preparedness, giving room for improvement.
Furthermore, policies are generally shaped at the national level rather than the regional level.Regions may place a higher emphasis on cross-border collaboration, experiencing the repercussions of lacking such policies, while it might be perceived as less urgent at the national level.Currently, cross-border collaboration mainly occurs at the operational level.Prevention officers, united in a cross-border collaboration know each other and establish direct contact during crises like COVID-19.However, this interaction is largely driven by personal connections rather than being supported by a structured government policy.Further investigation is needed to explore the added value of these collaborative networks.The present initiative for cross-border cooperation is largely driven by practical needs.Whether this level should also lead the initiation of national policies, should be further examined.
To make informed decisions about implementing, adjusting, easing, or suspending border restrictions, it is crucial to assess not only their effectiveness but also any unintended consequences, such as adverse impact on social, mental, and physical health, that may arise (36).
As the virus enters an endemic phase, it is important to update legal frameworks and establish enforceable measures to prepare for possible public health threats in the future.It  imposing border restrictions is detrimental and should only be implemented in crisis situations (37).Border restrictions should be temporary, proportionate, and coordinated between countries, rather than a unilateral action.Targeted measures are considered more effective and less disruptive (37).It has been suggested that border-related movements are not inherently more risky for SARS-CoV-2 transmission compared to in-country movements, and public health professionals have questioned the emphasis on restricting borders while leaving in-country movements largely unrestricted (5).If border restrictions or other measures are implemented, they should be aligned with neighboring countries to prevent adverse effects and impact on citizens (13,37,38).Therefore, cross-border collaboration on interventions that limit transmission but also minimize impact on citizens, especially in border regions, should be encouraged.

Conclusion
The COVID-19 pandemic has had significant implications for CBM in the EMR.We highlight the importance of considering the unique circumstances of border regions and the substantial impact of border restrictions on citizens' lives.Cross-border social networks, cross-border commuting, and the perception of measures played an important role in the changes observed in CBM and the negative experienced impact of border restrictions.Overall, our study shows the implications of the pandemic on CBM and emphasizes the importance of collaborative policies.In this way, public health goals can be prioritized while mitigating disruptions to citizens' lives and preserving the well-being of border regions.

FIGURE 1
FIGURE 1Timeline of data collection and border restrictions in the EMR.
highest rate in Germany and especially in Dutch participants.The latter observation might be explained by the fact that Dutch participants lived closest to a border; and as a result also might have been more impacted by border restrictions.Overall, 31% had at least one visit per month to cross-border social network members and 79% had at least one visit for everyday activities per month.The assessment of pre-pandemic CBM in the current study allowed for improved understanding of changes in CBM during the pandemic.

FIGURE 3
FIGURE 3Proportion of CBM per EMR-country before the pandemic and in spring and autumn 2021 for participants with pre-pandemic CBM (N = 2900).

TABLE 1
Proportions for pre-pandemic CBM in participants living in the EMR (N = 3,543).

TABLE 2
Proportions and multinomial regression analysis for changes in cross-border visits in participants with pre-pandemic CBM (N = 2,900).
Reference = no change in short cross-border visits.OR, odds ratio; 95%CI = 95% confidence interval.Nagelkerke pseudo-R 2 value of the multivariable model = 0.38.Decrease > 1 indicates a decrease of 1 or more cross-border visits per month in autumn 2021, compared to before the COVID-19 pandemic.Increase > 1 indicates an increase of 1 or more cross-border visits per month in autumn 2021, compared to before the COVID-19 pandemic.R1 = round 1 questionnaire.A For 'work from home' , all participants who were not working (e.g., retired, students) were grouped 'not applicable' .This group was then included in the categories of '(very) useful or neutral' for perceived usefulness, and '(very) easy or neutral' for perceived efficacy of working from home.

TABLE 3
Proportions and multinomial regression analysis for changes in cross-border visits to visit social network members in participants with pre-pandemic CBM for visiting social network members (N = 1,094).

TABLE 4
Proportions and multinomial regression analysis for changes in short cross-border visits for everyday activities in participants with pre-pandemic CBM for everyday activities (N = 2,789).

TABLE 5
Proportions and logistic regression analysis for negative experience with border restrictions in participants with baseline CBM (N = 2,900).

TABLE 5 (
Continued) has been established that in a highly globalized world and a Europe with open borders,