AUTHOR=Singh Mrigendra P. , Bharti Praveen K. , Rajvanshi Harsh , Sahu Ram S. , Jayswar Himanshu , Anvikar Anup R. , Lal Altaf A. TITLE=Malaria elimination: situation analysis of cases in India, the state of Madhya Pradesh in central India, and district Mandla of Madhya Pradesh JOURNAL=Frontiers in Public Health VOLUME=Volume 12 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1363736 DOI=10.3389/fpubh.2024.1363736 ISSN=2296-2565 ABSTRACT=India contributed about 66% of the malaria cases in the WHO South-East Asia region in 2022. In India, about 44% of cases have been reported to be disproportionately contributed by the ~27 districts . A comparative analysis of reported malaria cases between January 2017 and December 2022 was done in district Mandla, the site of a model malaria elimination demonstration project in Madhya Pradesh (MP), and India. Compared to 2017, the decrease in malaria cases in Mandla from 2018 to 2022 was higher than MP and the country. The reduction of cases was significant in 2018, 2019 and 2021 (p<0.01) (Mandla vs. MP), and highly significant during 2018-22 (p<0.001) (Mandla vs. India). Robust surveillance and real-time data-based decisions accompanied by appropriate management and operational controls and independent reviews, all designed for resource optimisation, were the reasons for eliminating indigenous malaria in district Mandla. The increase in infection rates in months immediately following rains suggests that surveillance, vector control and case management efforts should be specifically intensified for eliminating imported and indigenous cases in the near elimination districts to the national elimination goal of 2030.