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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Public Health</journal-id>
<journal-title>Frontiers in Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Public Health</abbrev-journal-title>
<issn pub-type="epub">2296-2565</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpubh.2024.1364296</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Socio-demographic, agricultural, and personal protective factors in relation to health literacy among farmers from all regions of Thailand</article-title>
</title-group>
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<name><surname>Sapbamrer</surname> <given-names>Ratana</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
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<name><surname>Sittitoon</surname> <given-names>Nalin</given-names></name>
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<name><surname>Thongtip</surname> <given-names>Sakesun</given-names></name>
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<name><surname>Chaipin</surname> <given-names>Eakasit</given-names></name>
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<name><surname>Sutalangka</surname> <given-names>Chatchada</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
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<name><surname>La-up</surname> <given-names>Aroon</given-names></name>
<xref ref-type="aff" rid="aff7"><sup>7</sup></xref>
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<name><surname>Thirarattanasunthon</surname> <given-names>Phiman</given-names></name>
<xref ref-type="aff" rid="aff8"><sup>8</sup></xref>
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<name><surname>Thammachai</surname> <given-names>Ajchamon</given-names></name>
<xref ref-type="aff" rid="aff9"><sup>9</sup></xref>
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<name><surname>Suwannakul</surname> <given-names>Boonsita</given-names></name>
<xref ref-type="aff" rid="aff9"><sup>9</sup></xref>
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<name><surname>Sangkarit</surname> <given-names>Noppharath</given-names></name>
<xref ref-type="aff" rid="aff9"><sup>9</sup></xref>
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<name><surname>Kitro</surname> <given-names>Amornphat</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
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<name><surname>Panumasvivat</surname> <given-names>Jinjuta</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
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<name><surname>Srisookkum</surname> <given-names>Taweewun</given-names></name>
<xref ref-type="aff" rid="aff10"><sup>10</sup></xref>
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<aff id="aff1"><sup>1</sup><institution>Department of Community Medicine, Faculty of Medicine, Chiang Mai University</institution>, <addr-line>Chiang Mai</addr-line>, <country>Thailand</country></aff>
<aff id="aff2"><sup>2</sup><institution>Environmental and Occupational Medicine Excellence Center (EnOMEC), Faculty of Medicine, Chiang Mai University</institution>, <addr-line>Chiang Mai</addr-line>, <country>Thailand</country></aff>
<aff id="aff3"><sup>3</sup><institution>School of Environmental Health, Institute of Public Health, Suranaree University of Technology</institution>, <addr-line>Nakhon Ratchasima</addr-line>, <country>Thailand</country></aff>
<aff id="aff4"><sup>4</sup><institution>Department of Environmental Health, School of Public Health, University of Phayao</institution>, <addr-line>Phayao</addr-line>, <country>Thailand</country></aff>
<aff id="aff5"><sup>5</sup><institution>Department of Public Health, Faculty of Science, Rajabhat Lampang University</institution>, <addr-line>Lampang</addr-line>, <country>Thailand</country></aff>
<aff id="aff6"><sup>6</sup><institution>Department of Physical Therapy, School of Integrative Medicine, Mae Fah Luang University</institution>, <addr-line>Chiang Rai</addr-line>, <country>Thailand</country></aff>
<aff id="aff7"><sup>7</sup><institution>Nakhonsawan Campus, Mahidol University</institution>, <addr-line>Nakhonsawan</addr-line>, <country>Thailand</country></aff>
<aff id="aff8"><sup>8</sup><institution>School of Public Health, Walailak University</institution>, <addr-line>Nakhon Si Thammarat</addr-line>, <country>Thailand</country></aff>
<aff id="aff9"><sup>9</sup><institution>Department of Physical Therapy, School of Allied Health Sciences, University of Phayao</institution>, <addr-line>Phayao</addr-line>, <country>Thailand</country></aff>
<aff id="aff10"><sup>10</sup><institution>Department of Community Health, School of Public Health, University of Phayao</institution>, <addr-line>Phayao</addr-line>, <country>Thailand</country></aff>
<author-notes>
<fn fn-type="edited-by" id="fn0001">
<p>Edited by: Kris A. G. Wyckhuys, Chrysalis Consulting, Vietnam</p>
</fn>
<fn fn-type="edited-by" id="fn0002">
<p>Reviewed by: Erma Sulistyaningsih, University of Jember, Indonesia</p>
<p>Oluseye Oludoye, Teesside University, United Kingdom</p>
</fn>
<corresp id="c001">&#x002A;Correspondence: Ratana Sapbamrer, <email>lekratana56@yahoo.com</email>; <email>ratana.sapbamrer@cmu.ac.th</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>25</day>
<month>03</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2024</year>
</pub-date>
<volume>12</volume>
<elocation-id>1364296</elocation-id>
<history>
<date date-type="received">
<day>02</day>
<month>01</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>07</day>
<month>03</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2024 Sapbamrer, Sittitoon, Thongtip, Chaipin, Sutalangka, La-up, Thirarattanasunthon, Thammachai, Suwannakul, Sangkarit, Kitro, Panumasvivat and Srisookkum.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Sapbamrer, Sittitoon, Thongtip, Chaipin, Sutalangka, La-up, Thirarattanasunthon, Thammachai, Suwannakul, Sangkarit, Kitro, Panumasvivat and Srisookkum</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<sec id="sec1">
<title>Introduction</title>
<p>Farmers are vulnerable to adverse health effects from pesticide exposure due to their health literacy (HL). Therefore, this study aims to investigate HL among farmers in four main regions of Thailand, investigating socio-demographics, agricultural, and personal protective factors to their HL.</p>
</sec>
<sec id="sec2">
<title>Methods</title>
<p>This cross-sectional design study was conducted on 4,035 farmers from January to July 2023. The European Health Literacy Survey Questionnaire-47 items were used to measure HL.</p>
</sec>
<sec id="sec3">
<title>Results</title>
<p>Thai farmers had a mean HL score of 34.7&#x2009;&#x00B1;&#x2009;8.7, and the farmers in the North region of Thailand had the highest frequency of limited HL (75.8%). Socio-demographic factors that were associated with HL included gender, region of living, marital status, education level, co-morbidity, and number of family members. Agricultural factors associated with HL included planting status, working hours on farm, spraying pesticides, harvesting crops, pesticide use of &#x003E;1 type, access information from government officers, access information from posters/brochures, information from online multimedia, and access information from neighbors. Personal protective factors that were associated with HL included wearing a hat, goggles, a rubber apron, and a long-sleeved shirt.</p>
</sec>
<sec id="sec4">
<title>Discussion</title>
<p>Our study recommends that strategies and interventions to enhance the HL of farmers should be focused on the target populations, which include men, widows, or divorced, those with low levels of education, those who have co-morbidities, and those who applied pesticides of more than 1 type and improper personal protective equipment (PPE) use. The primary emphasis needs to be on the North region of Thailand, making that the target area to improve health equity in Thailand. These efforts would enhance the HL of farmers and sustainably improve pesticide safety behavior. Additionally, there is an urgent need for supportive measures aimed at altering on-farm practices and promoting education on alternative pest management strategies, particularly non-chemical crop protection, to ensure sustainable agriculture.</p>
</sec>
</abstract>
<kwd-group>
<kwd>health literacy</kwd>
<kwd>pesticide</kwd>
<kwd>personal protective behavior</kwd>
<kwd>farmer</kwd>
<kwd>agricultural worker</kwd>
</kwd-group>
<contract-num rid="cn1">65-66</contract-num>
<contract-num rid="cn1">11466</contract-num>
<contract-sponsor id="cn1">Faculty of Medicine, Chiang Mai University<named-content content-type="fundref-id">10.13039/501100010731</named-content></contract-sponsor>
<counts>
<fig-count count="3"/>
<table-count count="5"/>
<equation-count count="1"/>
<ref-count count="46"/>
<page-count count="13"/>
<word-count count="8212"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Occupational Health and Safety</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="sec5">
<label>1</label>
<title>Introduction</title>
<p>Health literacy (HL) concerns the knowledge and competencies of individuals to obtain, understand, and use information and services necessary to make appropriate health-related decisions (<xref ref-type="bibr" rid="ref1">1</xref>, <xref ref-type="bibr" rid="ref2">2</xref>). HL is crucial for empowering people, prioritizing health concerns, and implementing health promotion at local, national, and global levels (<xref ref-type="bibr" rid="ref3">3</xref>, <xref ref-type="bibr" rid="ref4">4</xref>). The European HL Survey Questionnaire-47 items (HLS-EU-Q47) was developed to assess HL in a population based on a conceptual framework of three contexts of health domains (health care, disease prevention, and health promotion) across four information processing dimensions (access, understand, appraise, and apply) (<xref ref-type="bibr" rid="ref5">5</xref>). It has been used and validated worldwide across Europe, Asia, and some other countries (<xref ref-type="bibr" rid="ref6 ref7 ref8 ref9">6&#x2013;9</xref>). Most previous studies investigated HL among the general population and older people, and also socio-demographic factors. However, there is a notable gap in the literature concerning HL among farmers and agricultural workers, particularly in developing countries, with a specific emphasis on rural areas. Notably, there is a lack of studies on HL among populations in South America and Europe (<xref ref-type="bibr" rid="ref10">10</xref>). Given that approximately 78% of the world&#x2019;s poorest people reside in rural settings and depend largely on agriculture settings (<xref ref-type="bibr" rid="ref11">11</xref>, <xref ref-type="bibr" rid="ref12">12</xref>). The available studies indicated that HL levels among agricultural workers and rural residents tend to be lower compared to other population groups (<xref ref-type="bibr" rid="ref10">10</xref>, <xref ref-type="bibr" rid="ref13">13</xref>, <xref ref-type="bibr" rid="ref14">14</xref>). Studies conducted in developing countries have also identified significant differences in HL between rural and urban populations, in contrast to studies conducted in developed countries (<xref ref-type="bibr" rid="ref10">10</xref>). In Thailand, previous studies currently available also investigated HL in the general population and in older people (<xref ref-type="bibr" rid="ref7">7</xref>, <xref ref-type="bibr" rid="ref15">15</xref>). Despite several studies taking place in farmers in Thailand, these only investigated in specific geographical areas in north and North-East Thailand (<xref ref-type="bibr" rid="ref16">16</xref>, <xref ref-type="bibr" rid="ref17">17</xref>). Additionally, data regarding agricultural and protective behavior factors related to HL among farmers of all regions in Thailand are limited.</p>
<p>The agricultural sector in Thailand covers 6.4 million households and employs approximately 30% of the total labor force. However, the agricultural sector accounted for only 8.8% of gross domestic product (GDP) in 2022 (<xref ref-type="bibr" rid="ref18">18</xref>, <xref ref-type="bibr" rid="ref19">19</xref>). Even though it is only a small proportion of GDP, agriculture is crucial to Thai economics because the vast majority of the population still depend on it for their livelihood. The agricultural sector is currently facing several problems, including poverty, aging, land ownership, small-scale farming, and a limited farming portfolio (<xref ref-type="bibr" rid="ref19">19</xref>). In addition, they also face a problem of adverse health effects from pesticide use (<xref ref-type="bibr" rid="ref20">20</xref>). Thai farmers encounter a pressing issue concerning the misuse and overuse of pesticides. Approximately 80% of the pesticides applied exceed the socially optimal quantity (<xref ref-type="bibr" rid="ref21">21</xref>). The external costs associated with pesticide use are considerable, averaging USD 27.1 per hectare of agricultural land (<xref ref-type="bibr" rid="ref22">22</xref>). Moreover, pesticide prices would have minimal impact on curbing this overuse trend. Given these challenges, there is an urgent need for supportive measures aimed at altering on-farm practices and promoting education on alternative pest management strategies (<xref ref-type="bibr" rid="ref22">22</xref>, <xref ref-type="bibr" rid="ref23">23</xref>). In recent years, the Thai government has promoted the use of technology and innovation to enhance the quality of the agricultural products and to support farmers (<xref ref-type="bibr" rid="ref24">24</xref>). However, there is a lack of knowledge in alternative pest management and new technology in agriculture in Thai farmers due to their low levels of literacy (<xref ref-type="bibr" rid="ref19">19</xref>, <xref ref-type="bibr" rid="ref20">20</xref>, <xref ref-type="bibr" rid="ref25">25</xref>). As a result, farmers and agricultural workers are especially vulnerable to adverse health effects from pesticide exposure due to their HL. This study aims to investigate HL among farmers in four main regions of Thailand, examining socio-demographics, agricultural, and personal protective behavior factors in relation to their HL. The expected outcomes of this study are identification of the most vulnerable target population and areas to ensure that strategies and interventions should be focused on the area of highest need to enhance HL and reduce health disparities in Thailand.</p>
</sec>
<sec sec-type="methods" id="sec6">
<label>2</label>
<title>Methods</title>
<sec id="sec7">
<label>2.1</label>
<title>Setting and participants</title>
<p>Between January and July 2023, a study cross-sectional in design was conducted to survey HL among farmers in four regions of Thailand. The study&#x2019;s participants were farmers who used pesticides in agriculture and lived in four regions of Thailand, including Central, North, North-East, and South regions. The total agricultural population in Thailand&#x2019;s four regions was 6,744,856, with 1,249,490 people living in the Central region, 864,400 in the North, 3,503,763 in the North-East, and 1,127,203 in the South (<xref ref-type="bibr" rid="ref26">26</xref>). The EpiInfo program was used to calculate sample size, with an expected frequency of 40%, 2% confidence limits, and 99% confidence interval level, therefore 3,979 was the minimum sample size needed. Multi-stage stratified random sampling was employed, dividing the farmer populations into four strata based on the regions of Thailand. The study selected 31 provinces in Thailand, which are predominantly agricultural areas, as its focus. These provinces included seven from the Central region, four from the North, 14 from the North-East, and six from the South. Seven provinces from the Central region, including Nakhon Sawan, Lopburi, Nakhon Prathom, Saraburi, Sing Buri, Ayutthaya, and Chai Nat provinces, were chosen to represent the central region, representing 13.7% of the Central. Four provinces from the North region, including Lam Pang, Phayao, Chiang Mai, and Chiang Rai provinces, were designated as representative areas of the North, representing 23.5% of the North. Fourteen provinces from the North-East region, including Ubon Ratchathani, Sisaket, Surin, Buriram, Nakhon Ratchasima, Udon Thani, Mukdahan, Kalasin, Amnat Charoen, Roi Et, Yasothon, Chaiyaphum, Nakhon Phanom, and Khon Kaen provinces were chosen to represent the North-East, representing 70% of the North-East. Six provinces from the South region, including Pattani, Yala, Surat Thani, Songkhla, Narathiwat, and Nakhon Si Thammarat provinces were identified as representative areas of the South, representing 42.9% of the North-East. Samples were systematically drawn from agricultural and rural communities within each province. Population proportional sampling was used, ensuring that the sample size for each stratum was directly proportional to the population size of that specific stratum. The actual sample sizes were 746 from the Central region, 586 from the North, 2,065 from the North-East, and 638 from the South.</p>
</sec>
<sec id="sec8">
<label>2.2</label>
<title>Interviews</title>
<p>Due to the illiteracy of the majority of Thai farmers face-to-face interviews were conducted. The participants were interviewed with specifically trained interviewers. This study involved researchers located across all regions of Thailand. To reduce cultural and language differences in each region of Thailand, researchers in each region provided training to interviewers on purpose of the study, questions in the questionnaire, questions and scales in HLS-EU-Q47, and the need for professional and consistent performance by the interviewers. These interviewers were either healthcare personnels or bachelor students in health sciences who resided in the study areas and were fluent in the local languages spoken in those areas.</p>
<p>The questions on the interview form were divided into four sections, including socio-demographic characteristics, agricultural information, personal protective behavior, and HL. Socio-demographic data included age (years), gender (male or female), marital status (single, married, or divorced or widow), education level (elementary school or lower, secondary school, or Bachelor degree or higher), monthly income (&#x2264;250 US Dollars or&#x2009;&#x003E;&#x2009;250 US Dollars), co-morbidity (yes or no), number of family member (persons), cigarette smoker (yes or no), alcohol consumption (yes or no), and acting as a health volunteer in the village (yes or no). Agricultural information included planting area (acres), planting status (planting in own area or as a hiree), working hours on farm [2&#x2013;4&#x2009;h (h)/day or&#x2009;&#x003E;&#x2009;4&#x2009;h./day], type of crop planting (rice, corn, para rubber, cassava, sugarcane, palm, vegetable, fruit, flower, or other), task on the farm (mixing pesticides, spraying pesticides, or harvesting crops), type of pesticide use (herbicide, insecticide, fungicide, molluscicide, rodenticide, or nematocide), and source of pesticide information (pesticide merchants, neighbors, government officers, online multimedia, television, posters/brochures, or radio). Regarding personal protective behavior, the questions asked about personal protective equipment (PPE) use during pesticide application including wearing of a long-sleeved shirt, long-sleeved trousers, hat, gloves, goggles, mask, boots, and rubber apron.</p>
<p>HLS-EU-Q47 was used to measure HL (<xref ref-type="bibr" rid="ref5">5</xref>). The HLS-EU-Q47 includes 47 items, each item being rated on a four-point Likert rating scale, specifically: very difficult (1), difficult (2), easy (3), and very easy (4). The conceptual model of the HLS-EU-Q47 distinguishes between three contexts of HL (health care, disease prevention, and health promotion) and four competencies to deal with information relative to health (access, understand, appraise, and apply). These three contexts and the four competencies were then used to create seven subdomains for measuring HL. The seven subdomains were as follows: Subdomain1: health care (16 items); Subdomain 2: disease prevention (15 items); Subdomain 3: health promotion (16 items); Subdomain 4: access/obtain information relevant to health (13 items); Subdomain 5: understand information relevant to health (11 items); Subdomain 6: process/appraise information relevant to health (12 items); and Subdomain 7: apply/use information relevant to health (11 items). The HL index was standardized to a scale of 0&#x2013;50 using the formula:</p>
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</mml:mfenced>
<mml:mo>&#x00D7;</mml:mo>
<mml:mfenced open="(" close=")">
<mml:mrow>
<mml:mn>50</mml:mn>
<mml:mo stretchy="true">/</mml:mo>
<mml:mn>3</mml:mn>
</mml:mrow>
</mml:mfenced>
</mml:math>
</disp-formula>
<p>where,</p>
<p>HL index was the HL index calculated.</p>
<p>Mean was the mean of HL for each index.</p>
<p>Health literacy (HL) was classified into four levels, specifically: inadequate HL (scores of 0&#x2013;25), likely problematic HL (&#x003E;25&#x2013;33 scores), likely sufficient HL (&#x003E;33&#x2013;42 scores), and excellent HL (&#x003E;42&#x2013;50 scores). To detect vulnerable groups, inadequate HL and likely problematic HL were combined and called limited HL (scores of 0&#x2013;33).</p>
<p>The HLS-EU-Q47 was translated from English into Thai language using forward-only translation by three native Thai researchers who were fluent in English (RS, JJ, and AK). To reduce cultural and language differences in each region, The Thai version of The HLS-EU-Q47 were verified and edited by the seven researches from all regions of Thailand (EC, CS, PT, AT, BS, NSa, and TS). Validity was tested by three experts (ST, NSi, and AL). Pilot testing was performed in 10 farmers from all regions. Minor wording, typographical errors, and grammar were corrected, and the Thai final version was prepared by RS. The index of congruence (IOC) score was &#x003E;0.5. Internal consistency was tested using Cronbach&#x2019;s alpha coefficient, and the coefficient of The HLS-EU-Q47 in the Thai version was 0.876 therefore the questionnaire was a reliable tool.</p>
</sec>
<sec id="sec9">
<label>2.3</label>
<title>Ethical approval</title>
<p>The study was approved by the Research Ethics Committee of the Faculty of Medicine, Chiang Mai University, Thailand (No. 419/2022). Prior to the interviews, the participants were required to complete a written informed consent form. The participants were informed regarding the confidentiality and data protection protocols in place. No photographic or video recordings of participants were made. Furthermore, personal identifiers such as names, addresses, and telephone numbers were not solicited in the interview documentation. Moreover, access to the dataset files is restricted solely to the researcher team, safeguarded by password protection.</p>
</sec>
<sec id="sec10">
<label>2.4</label>
<title>Statistical analysis</title>
<p>Descriptive statistics, including frequency (n), percentage (%), mean, and standard deviation (SD) were used. Univariable analysis, including independent <italic>t</italic>-test, and one-way ANOVA were used to investigate the variables associated with the HL score. The variables that had a significant (<italic>p</italic> value&#x003C;0.05) from the univariable analysis were included in the multivariable model. Therefore, 29 variables from the univariable analysis that were significant were included into the model of multiple linear regression analysis (<xref ref-type="fig" rid="fig1">Figure 1</xref>).The multiple linear regression analysis was used to investigate the factors associated with HL score. Beta, standard error (SE) and 95% confidence intervals (95%CI) are presented.</p>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>Factors associated with health literacy among Thai farmers.</p>
</caption>
<graphic xlink:href="fpubh-12-1364296-g001.tif"/>
</fig>
</sec>
</sec>
<sec sec-type="results" id="sec11">
<label>3</label>
<title>Results</title>
<sec id="sec12">
<label>3.1</label>
<title>Socio-demographics and agricultural information among farmers</title>
<p>The mean age of farmers was 52.5&#x2009;&#x00B1;&#x2009;10.8&#x2009;years, and 45.6% of them were male. Approximately 77% of farmers were married, 63% had elementary school or lower levels of education, and 66.8% had a monthly income &#x2264;250 US Dollars. A total of 19% of the farmers smoked cigarettes while 31.6% drank alcohol. Approximately 29.6% of farmers had a co-morbidity, and 27.3% were health volunteers in their village (<xref ref-type="table" rid="tab1">Table 1</xref>).</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Socio-demographic characteristics among farmers classified by regions of Thailand.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Parameters</th>
<th/>
<th align="center" valign="top">Total (<italic>N</italic> =&#x2009;4,035)</th>
<th align="center" valign="top">North-East (<italic>n</italic> =&#x2009;2,065)</th>
<th align="center" valign="top">Central (<italic>n</italic>&#x2009;=&#x2009;746)</th>
<th align="center" valign="top">South (<italic>n</italic>&#x2009;=&#x2009;638)</th>
<th align="center" valign="top">North (<italic>n</italic> =&#x2009;586)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Age (years old), mean&#x2009;&#x00B1;&#x2009;SD.</td>
<td/>
<td align="center" valign="top">52.5&#x2009;&#x00B1;&#x2009;10.8</td>
<td align="center" valign="top">52.9&#x2009;&#x00B1;&#x2009;11.1</td>
<td align="center" valign="top">52.6&#x2009;&#x00B1;&#x2009;10.9</td>
<td align="center" valign="top">48.7&#x2009;&#x00B1;&#x2009;10.9</td>
<td align="center" valign="top">55.0&#x2009;&#x00B1;&#x2009;8.1</td>
</tr>
<tr>
<td align="left" valign="top">Gender, <italic>n</italic> (%)</td>
<td align="left" valign="top">Male</td>
<td align="center" valign="top">1841 (45.6)</td>
<td align="center" valign="top">1,019 (49.3)</td>
<td align="center" valign="top">287 (38.5)</td>
<td align="center" valign="top">200 (31.3)</td>
<td align="center" valign="top">335 (57.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Female</td>
<td align="center" valign="top">2,194 (54.4)</td>
<td align="center" valign="top">1,046 (50.7)</td>
<td align="center" valign="top">459 (61.5)</td>
<td align="center" valign="top">438 (68.7)</td>
<td align="center" valign="top">251 (42.8)</td>
</tr>
<tr>
<td align="left" valign="top">Marital status, <italic>n</italic> (%)</td>
<td align="left" valign="top">Single</td>
<td align="center" valign="top">570 (14.1)</td>
<td align="center" valign="top">318 (15.4)</td>
<td align="center" valign="top">122 (16.4)</td>
<td align="center" valign="top">77 (12.1)</td>
<td align="center" valign="top">53 (9.0)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Married</td>
<td align="center" valign="top">3,116 (77.2)</td>
<td align="center" valign="top">1,613 (78.1)</td>
<td align="center" valign="top">522 (70.0)</td>
<td align="center" valign="top">539 (84.5)</td>
<td align="center" valign="top">442 (75.4)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Divorced/widow</td>
<td align="center" valign="top">349 (8.6)</td>
<td align="center" valign="top">134 (6.5)</td>
<td align="center" valign="top">102 (13.7)</td>
<td align="center" valign="top">22 (3.4)</td>
<td align="center" valign="top">91 (15.5)</td>
</tr>
<tr>
<td align="left" valign="top">Education level, <italic>n</italic> (%)</td>
<td align="left" valign="top">Elementary school or lower</td>
<td align="center" valign="top">2,542 (63.0)</td>
<td align="center" valign="top">1,257 (60.9)</td>
<td align="center" valign="top">387 (51.9)</td>
<td align="center" valign="top">375 (58.8)</td>
<td align="center" valign="top">523 (89.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Secondary school</td>
<td align="center" valign="top">1,202 (29.8)</td>
<td align="center" valign="top">676 (32.7)</td>
<td align="center" valign="top">277 (37.1)</td>
<td align="center" valign="top">190 (29.8)</td>
<td align="center" valign="top">59 (10.1)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Bachelor degree or higher</td>
<td align="center" valign="top">291 (7.2)</td>
<td align="center" valign="top">132 (6.4)</td>
<td align="center" valign="top">82 (11.1)</td>
<td align="center" valign="top">73 (11.4)</td>
<td align="center" valign="top">4 (0.7)</td>
</tr>
<tr>
<td align="left" valign="top">Monthly income, <italic>n</italic> (%)</td>
<td align="left" valign="top">&#x2264;250 US Dollars</td>
<td align="center" valign="top">2,695 (66.8)</td>
<td align="center" valign="top">1,621 (78.5)</td>
<td align="center" valign="top">381 (51.1)</td>
<td align="center" valign="top">264 (41.4)</td>
<td align="center" valign="top">429 (73.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E;250 US Dollars</td>
<td align="center" valign="top">1,340 (33.2)</td>
<td align="center" valign="top">444 (21.5)</td>
<td align="center" valign="top">365 (48.9)</td>
<td align="center" valign="top">374 (58.6)</td>
<td align="center" valign="top">157 (26.8)</td>
</tr>
<tr>
<td align="left" valign="top">Co-morbidity, <italic>n</italic> (%)</td>
<td/>
<td align="center" valign="top">1,194 (29.6)</td>
<td align="center" valign="top">432 (20.9)</td>
<td align="center" valign="top">381 (51.1)</td>
<td align="center" valign="top">200 (31.3)</td>
<td align="center" valign="top">181 (30.9)</td>
</tr>
<tr>
<td align="left" valign="top">Family members (persons), mean&#x2009;&#x00B1;&#x2009;SD</td>
<td/>
<td align="center" valign="top">4&#x2009;&#x00B1;&#x2009;2</td>
<td align="center" valign="top">4&#x2009;&#x00B1;&#x2009;2</td>
<td align="center" valign="top">4&#x2009;&#x00B1;&#x2009;2</td>
<td align="center" valign="top">4&#x2009;&#x00B1;&#x2009;2</td>
<td align="center" valign="top">3&#x2009;&#x00B1;&#x2009;1</td>
</tr>
<tr>
<td align="left" valign="top">Smoking cigarette, <italic>n</italic> (%)</td>
<td/>
<td align="center" valign="top">767 (19.0)</td>
<td align="center" valign="top">116 (15.5)</td>
<td align="center" valign="top">403 (19.5)</td>
<td align="center" valign="top">84 (13.2)</td>
<td align="center" valign="top">164 (28.0)</td>
</tr>
<tr>
<td align="left" valign="top">Alcohol consumption, <italic>n</italic> (%)</td>
<td/>
<td align="center" valign="top">1,275 (31.6)</td>
<td align="center" valign="top">692 (33.5)</td>
<td align="center" valign="top">204 (27.3)</td>
<td align="center" valign="top">36 (5.6)</td>
<td align="center" valign="top">343 (58.5)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Acting as a health volunteer in village, <italic>n</italic> (%)</td>
<td align="center" valign="top">1,102 (27.3)</td>
<td align="center" valign="top">431 (20.9)</td>
<td align="center" valign="top">369 (49.5)</td>
<td align="center" valign="top">129 (20.2)</td>
<td align="center" valign="top">173 (29.5)</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>n, frequency; %, percentage; SD, Standard deviation.</p>
</table-wrap-foot>
</table-wrap>
<p>Regarding agricultural information, 60.6% of farmers had a planting area&#x2009;&#x2264;&#x2009;4 acres, 78.2% planted in their own area, and 54.4% worked on the farm 2&#x2013;4&#x2009;h/day. The most frequently planted crops were rice (76.7%), followed by vegetables (34.2%) and then fruit (16.0%). The most common pesticides used were herbicides (77.3%), followed by insecticides (68.8%) and fungicides (54.5%). About 75.4% of the farmers used more than one type of pesticide on their farm. The farmers&#x2019; tasks included mixing pesticide (62.1%), spraying pesticides (61.6%), and harvesting crops (65.9%). Pesticide merchants were the most frequent sources of information (62.3%), followed by neighbors (53.3%) and government officials (33.4%) (<xref ref-type="table" rid="tab2">Table 2</xref>).</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Agricultural information among farmers classified by regions of Thailand.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Parameters</th>
<th/>
<th align="center" valign="top">Total (<italic>N</italic> =&#x2009;4,035)</th>
<th align="center" valign="top">North-east (<italic>n</italic> =&#x2009;2,065)</th>
<th align="center" valign="top">Central (<italic>n</italic>&#x2009;=&#x2009;746)</th>
<th align="center" valign="top">South (<italic>n</italic>&#x2009;=&#x2009;638)</th>
<th align="center" valign="top">North (<italic>n</italic> =&#x2009;586)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Agricultural area (acres), <italic>n</italic> (%)</td>
<td align="left" valign="top">&#x2264; 4 acres</td>
<td align="center" valign="top">2,446 (60.6)</td>
<td align="center" valign="top">1,289 (62.4)</td>
<td align="center" valign="top">162 (21.7)</td>
<td align="center" valign="top">514 (80.6)</td>
<td align="center" valign="top">481 (82.1)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E; 4 acres</td>
<td align="center" valign="top">1,589 (39.4)</td>
<td align="center" valign="top">776 (37.6)</td>
<td align="center" valign="top">584 (78.3)</td>
<td align="center" valign="top">124 (19.4)</td>
<td align="center" valign="top">105 (17.9)</td>
</tr>
<tr>
<td align="left" valign="top">Planting status, <italic>n</italic> (%)</td>
<td align="left" valign="top">Planting in own area</td>
<td align="center" valign="top">3,157 (78.2)</td>
<td align="center" valign="top">1,903 (92.2)</td>
<td align="center" valign="top">453 (60.7)</td>
<td align="center" valign="top">552 (86.5)</td>
<td align="center" valign="top">249 (42.5)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Hiree</td>
<td align="center" valign="top">878 (21.8)</td>
<td align="center" valign="top">162 (7.8)</td>
<td align="center" valign="top">293 (39.3)</td>
<td align="center" valign="top">86 (13.5)</td>
<td align="center" valign="top">337 (57.5)</td>
</tr>
<tr>
<td align="left" valign="top">Working hours on farm, <italic>n</italic> (%)</td>
<td align="left" valign="top">2&#x2013;4&#x2009;h./day</td>
<td align="center" valign="top">2,196 (54.4)</td>
<td align="center" valign="top">1,377 (66.7)</td>
<td align="center" valign="top">279 (37.4)</td>
<td align="center" valign="top">448 (70.2)</td>
<td align="center" valign="top">92 (15.7)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E;4&#x2009;h./day</td>
<td align="center" valign="top">1,839 (45.6)</td>
<td align="center" valign="top">688 (33.3)</td>
<td align="center" valign="top">467 (62.6)</td>
<td align="center" valign="top">190 (29.8)</td>
<td align="center" valign="top">494 (84.3)</td>
</tr>
<tr>
<td align="left" valign="top">Type of crop planting, <italic>n</italic> (%)</td>
<td align="left" valign="top">Rice</td>
<td align="center" valign="top">3,094 (76.7)</td>
<td align="center" valign="top">1,895 (91.8)</td>
<td align="center" valign="top">581 (77.9)</td>
<td align="center" valign="top">79 (12.4)</td>
<td align="center" valign="top">539 (92.0)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Vegetable</td>
<td align="center" valign="top">1,379 (34.2)</td>
<td align="center" valign="top">792 (38.4)</td>
<td align="center" valign="top">306 (41.0)</td>
<td align="center" valign="top">188 (29.5)</td>
<td align="center" valign="top">93 (15.9)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Fruit</td>
<td align="center" valign="top">646 (16.0)</td>
<td align="center" valign="top">236 (11.4)</td>
<td align="center" valign="top">200 (26.8)</td>
<td align="center" valign="top">177 (27.7)</td>
<td align="center" valign="top">33 (5.6)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Para rubber</td>
<td align="center" valign="top">558 (13.8)</td>
<td align="center" valign="top">129 (6.2)</td>
<td align="center" valign="top">4 (0.5)</td>
<td align="center" valign="top">409 (64.1)</td>
<td align="center" valign="top">16 (2.7)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Corn</td>
<td align="center" valign="top">460 (11.4)</td>
<td align="center" valign="top">131 (6.3)</td>
<td align="center" valign="top">196 (26.3)</td>
<td align="center" valign="top">53 (8.3)</td>
<td align="center" valign="top">80 (13.7)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Cassava</td>
<td align="center" valign="top">430 (10.7)</td>
<td align="center" valign="top">296 (14.3)</td>
<td align="center" valign="top">48 (6.4)</td>
<td align="center" valign="top">28 (4.4)</td>
<td align="center" valign="top">58 (9.9)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Flower</td>
<td align="center" valign="top">351 (8.7)</td>
<td align="center" valign="top">204 (9.9)</td>
<td align="center" valign="top">122 (16.4)</td>
<td align="center" valign="top">24 (3.8)</td>
<td align="center" valign="top">1 (0.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Sugarcane</td>
<td align="center" valign="top">278 (6.9)</td>
<td align="center" valign="top">176 (8.5)</td>
<td align="center" valign="top">78 (10.5)</td>
<td align="center" valign="top">24 (3.8)</td>
<td align="center" valign="top">0 (0)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Palm</td>
<td align="center" valign="top">141 (3.5)</td>
<td align="center" valign="top">13 (0.6)</td>
<td align="center" valign="top">1 (0.1)</td>
<td align="center" valign="top">126 (19.7)</td>
<td align="center" valign="top">1 (0.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">other</td>
<td align="center" valign="top">208 (5.2)</td>
<td align="center" valign="top">83 (4.0)</td>
<td align="center" valign="top">32 (4.3)</td>
<td align="center" valign="top">74 (11.6)</td>
<td align="center" valign="top">19 (3.2)</td>
</tr>
<tr>
<td align="left" valign="top">Task on farm, <italic>n</italic> (%)</td>
<td align="left" valign="top">Mixing pesticides</td>
<td align="center" valign="top">2,505 (62.1)</td>
<td align="center" valign="top">1,243 (60.2)</td>
<td align="center" valign="top">527 (70.6)</td>
<td align="center" valign="top">322 (50.5)</td>
<td align="center" valign="top">413 (70.5)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Spraying pesticides</td>
<td align="center" valign="top">2,486 (61.6)</td>
<td align="center" valign="top">1,196 (57.9)</td>
<td align="center" valign="top">531 (71.2)</td>
<td align="center" valign="top">324 (50.8)</td>
<td align="center" valign="top">435 (74.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Harvesting crops</td>
<td align="center" valign="top">2,660 (65.9)</td>
<td align="center" valign="top">1,317 (63.8)</td>
<td align="center" valign="top">474 (63.5)</td>
<td align="center" valign="top">341 (53.4)</td>
<td align="center" valign="top">528 (90.1)</td>
</tr>
<tr>
<td align="left" valign="top">Type of pesticides use, <italic>n</italic> (%)</td>
<td align="left" valign="top">Herbicides</td>
<td align="center" valign="top">3,120 (77.3)</td>
<td align="center" valign="top">1,503 (72.8)</td>
<td align="center" valign="top">652 (81.4)</td>
<td align="center" valign="top">403 (63.2)</td>
<td align="center" valign="top">562 (95.9)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Insecticides</td>
<td align="center" valign="top">2,775 (68.8)</td>
<td align="center" valign="top">1,392 (67.4)</td>
<td align="center" valign="top">644 (86.3)</td>
<td align="center" valign="top">278 (43.6)</td>
<td align="center" valign="top">461 (78.7)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Fungicides</td>
<td align="center" valign="top">2,198 (54.5)</td>
<td align="center" valign="top">1,1,53 (55.8)</td>
<td align="center" valign="top">554 (74.3)</td>
<td align="center" valign="top">150 (23.5)</td>
<td align="center" valign="top">341 (58.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Nematocides</td>
<td align="center" valign="top">1,986 (49.2)</td>
<td align="center" valign="top">998 (48.3)</td>
<td align="center" valign="top">563 (75.5)</td>
<td align="center" valign="top">130 (20.4)</td>
<td align="center" valign="top">295 (50.3)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Molluscicides</td>
<td align="center" valign="top">1,580 (39.2)</td>
<td align="center" valign="top">876 (42.4)</td>
<td align="center" valign="top">383 (51.3)</td>
<td align="center" valign="top">40 (6.3)</td>
<td align="center" valign="top">281 (48.0)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Rodenticides</td>
<td align="center" valign="top">1,471 (36.5)</td>
<td align="center" valign="top">792 (38.4)</td>
<td align="center" valign="top">418 (56.0)</td>
<td align="center" valign="top">95 (14.9)</td>
<td align="center" valign="top">166 (28.3)</td>
</tr>
<tr>
<td align="left" valign="top">Number of pesticides used, <italic>n</italic> (%)</td>
<td align="left" valign="top">1 type</td>
<td align="center" valign="top">993 (24.6)</td>
<td align="center" valign="top">533 (25.8)</td>
<td align="center" valign="top">78 (10.5)</td>
<td align="center" valign="top">340 (53.3)</td>
<td align="center" valign="top">42 (7.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E; 1 type</td>
<td align="center" valign="top">3,042 (75.4)</td>
<td align="center" valign="top">1,532 (74.2)</td>
<td align="center" valign="top">668 (89.5)</td>
<td align="center" valign="top">298 (46.7)</td>
<td align="center" valign="top">544 (92.8)</td>
</tr>
<tr>
<td align="left" valign="top">Source of pesticide information, <italic>n</italic> (%)</td>
<td align="left" valign="top">Pesticide merchants</td>
<td align="center" valign="top">2,514 (62.3)</td>
<td align="center" valign="top">1,219 (59.0)</td>
<td align="center" valign="top">583 (78.2)</td>
<td align="center" valign="top">296 (46.4)</td>
<td align="center" valign="top">416 (71.0)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Neighbors</td>
<td align="center" valign="top">2,151 (53.3)</td>
<td align="center" valign="top">1,157 (56.0)</td>
<td align="center" valign="top">393 (52.7)</td>
<td align="center" valign="top">391 (61.3)</td>
<td align="center" valign="top">210 (35.8)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Government officers</td>
<td align="center" valign="top">1,346 (33.4)</td>
<td align="center" valign="top">861 (41.7)</td>
<td align="center" valign="top">279 (37.4)</td>
<td align="center" valign="top">108 (16.9)</td>
<td align="center" valign="top">98 (16.7)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Online multimedia</td>
<td align="center" valign="top">961 (23.8)</td>
<td align="center" valign="top">351 (17.0)</td>
<td align="center" valign="top">325 (43.6)</td>
<td align="center" valign="top">210 (32.9)</td>
<td align="center" valign="top">75 (12.8)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Television</td>
<td align="center" valign="top">833 (20.6)</td>
<td align="center" valign="top">324 (15.7)</td>
<td align="center" valign="top">231 (31.0)</td>
<td align="center" valign="top">207 (32.4)</td>
<td align="center" valign="top">71 (12.1)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Posters/brochures</td>
<td align="center" valign="top">661 (16.4)</td>
<td align="center" valign="top">392 (19.0)</td>
<td align="center" valign="top">133 (17.8)</td>
<td align="center" valign="top">41 (6.4)</td>
<td align="center" valign="top">95 (16.2)</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Radio</td>
<td align="center" valign="top">576 (14.3)</td>
<td align="center" valign="top">258 (12.5)</td>
<td align="center" valign="top">214 (28.7)</td>
<td align="center" valign="top">60 (9.4)</td>
<td align="center" valign="top">44 (7.5)</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec13">
<label>3.2</label>
<title>PPE use during pesticide application among farmers</title>
<p>The PPE that farmers always wore while applying pesticides were long-sleeved trousers (72.4%), followed by boots (70.7%), and a long-sleeved shirt (70.3%), while the PPE that farmers never wore while applying pesticides were a rubber apron (13.8%), goggles (6.8%), and a hat (3.3%) (<xref ref-type="fig" rid="fig2">Figure 2</xref>).</p>
<fig position="float" id="fig2">
<label>Figure 2</label>
<caption>
<p>PPE use during pesticide application.</p>
</caption>
<graphic xlink:href="fpubh-12-1364296-g002.tif"/>
</fig>
</sec>
<sec id="sec14">
<label>3.3</label>
<title>HL among farmers</title>
<p>The average HL score among Thai farmers was 34.7&#x2009;&#x00B1;&#x2009;8.7. The North-east region had the highest mean HL score (36.8&#x2009;&#x00B1;&#x2009;8.9), followed by Central (34.6&#x2009;&#x00B1;&#x2009;5.9), South (33.5&#x2009;&#x00B1;&#x2009;9.3), and North (29.0&#x2009;&#x00B1;&#x2009;6.9). Considering the subdomains of HL scores, HL of all subdomains for the North-east region had the highest HL scores, while HL of all subdomains in the North had the lowest HL scores (<xref ref-type="table" rid="tab3">Table 3</xref>). To detect groups most vulnerable to low levels of HL in each region, the results were analyzed and showed that farmers in the North region had the highest frequency of limited HL (75.8%), followed by the South (50.7%), the Central (37.4%), and the North-East (36.7%) (<xref ref-type="fig" rid="fig3">Figure 3</xref>).</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>HL scores among farmers, classified by regions of Thailand.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Parameters</th>
<th align="center" valign="top" colspan="5">Mean&#x2009;&#x00B1;&#x2009;SD.</th>
<th/>
</tr>
<tr>
<th/>
<th align="center" valign="top">Total (<italic>N</italic> =&#x2009;4,035)</th>
<th align="center" valign="top">North-east (<italic>n</italic>&#x2009;=&#x2009;2,065)<sup>a</sup></th>
<th align="center" valign="top">Central (<italic>n</italic>&#x2009;=&#x2009;746)<sup>b</sup></th>
<th align="center" valign="top">South (<italic>n</italic>&#x2009;=&#x2009;638)<sup>c</sup></th>
<th align="center" valign="top">North (<italic>n</italic>&#x2009;=&#x2009;586)<sup>d</sup></th>
<th align="center" valign="top"><italic>p</italic> value</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Total scores HL</td>
<td align="center" valign="top">34.7&#x2009;&#x00B1;&#x2009;8.7</td>
<td align="center" valign="top">36.8&#x2009;&#x00B1;&#x2009;8.9</td>
<td align="center" valign="top">34.6&#x2009;&#x00B1;&#x2009;5.9</td>
<td align="center" valign="top">33.5&#x2009;&#x00B1;&#x2009;9.3</td>
<td align="center" valign="top">29.0&#x2009;&#x00B1;&#x2009;6.9</td>
<td align="center" valign="top">&#x003C;0.001<sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 1: Access/Obtain information relevant health</td>
<td align="center" valign="top">33.8&#x2009;&#x00B1;&#x2009;9.4</td>
<td align="center" valign="top">35.6&#x2009;&#x00B1;&#x2009;9.5</td>
<td align="center" valign="top">34.7&#x2009;&#x00B1;&#x2009;6.5</td>
<td align="center" valign="top">33.3&#x2009;&#x00B1;&#x2009;9.4</td>
<td align="center" valign="top">26.5&#x2009;&#x00B1;&#x2009;8.3</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 2: Understand information relevant to health</td>
<td align="center" valign="top">36.3&#x2009;&#x00B1;&#x2009;8.9</td>
<td align="center" valign="top">38.5&#x2009;&#x00B1;&#x2009;9.1</td>
<td align="center" valign="top">36.2&#x2009;&#x00B1;&#x2009;6.4</td>
<td align="center" valign="top">34.0&#x2009;&#x00B1;&#x2009;9.5</td>
<td align="center" valign="top">31.2&#x2009;&#x00B1;&#x2009;7.7</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 3: Process/appraise information relevant to health</td>
<td align="center" valign="top">33.7&#x2009;&#x00B1;&#x2009;9.3</td>
<td align="center" valign="top">35.9&#x2009;&#x00B1;&#x2009;9.5</td>
<td align="center" valign="top">32.2&#x2009;&#x00B1;&#x2009;7.8</td>
<td align="center" valign="top">33.5&#x2009;&#x00B1;&#x2009;9.4</td>
<td align="center" valign="top">28.0&#x2009;&#x00B1;&#x2009;7.2</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 4: Apply/use information relevant to health</td>
<td align="center" valign="top">35.4&#x2009;&#x00B1;&#x2009;8.8</td>
<td align="center" valign="top">37.3&#x2009;&#x00B1;&#x2009;9.2</td>
<td align="center" valign="top">35.5&#x2009;&#x00B1;&#x2009;6.2</td>
<td align="center" valign="top">33.3&#x2009;&#x00B1;&#x2009;9.8</td>
<td align="center" valign="top">30.9&#x2009;&#x00B1;&#x2009;6.3</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 5: Health care</td>
<td align="center" valign="top">35.0&#x2009;&#x00B1;&#x2009;8.9</td>
<td align="center" valign="top">36.9&#x2009;&#x00B1;&#x2009;9.4</td>
<td align="center" valign="top">35.5&#x2009;&#x00B1;&#x2009;6.4</td>
<td align="center" valign="top">33.6&#x2009;&#x00B1;&#x2009;9.6</td>
<td align="center" valign="top">29.5&#x2009;&#x00B1;&#x2009;6.7</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 6: Disease prevention</td>
<td align="center" valign="top">33.7&#x2009;&#x00B1;&#x2009;9.4</td>
<td align="center" valign="top">35.9&#x2009;&#x00B1;&#x2009;9.7</td>
<td align="center" valign="top">32.5&#x2009;&#x00B1;&#x2009;7.4</td>
<td align="center" valign="top">32.9&#x2009;&#x00B1;&#x2009;9.9</td>
<td align="center" valign="top">28.2&#x2009;&#x00B1;&#x2009;7.2</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
<tr>
<td align="left" valign="top">Sub-domain 7: Health promotion</td>
<td align="center" valign="top">35.4&#x2009;&#x00B1;&#x2009;9.2</td>
<td align="center" valign="top">37.4&#x2009;&#x00B1;&#x2009;9.3</td>
<td align="center" valign="top">35.6&#x2009;&#x00B1;&#x2009;6.7</td>
<td align="center" valign="top">33.9&#x2009;&#x00B1;&#x2009;9.5</td>
<td align="center" valign="top">29.3&#x2009;&#x00B1;&#x2009;9.3</td>
<td align="center" valign="top">&#x003C;0.001 <sup>ab,ac,ad,bc,bd,cd</sup></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>The different letters refer to significant differences.</p>
</table-wrap-foot>
</table-wrap>
<fig position="float" id="fig3">
<label>Figure 3</label>
<caption>
<p>Health literacy among farmers, classified by regions of Thailand.</p>
</caption>
<graphic xlink:href="fpubh-12-1364296-g003.tif"/>
</fig>
</sec>
<sec id="sec15">
<label>3.4</label>
<title>Factors related to HL in farmers</title>
<p>Univariable analysis showing the factors associated with HL scores among Thai farmers are presented in <xref ref-type="table" rid="tab4">Table 4</xref>, and multiple linear regression analysis are presented in <xref ref-type="table" rid="tab5">Table 5</xref>.</p>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption>
<p>Univariable analysis for investigating factors associated with HL among Thai farmers.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Parameters</th>
<th/>
<th/>
<th align="center" valign="top">HL scores (mean&#x2009;&#x00B1;&#x2009;SD)</th>
<th align="center" valign="top"><italic>p</italic> value</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Gender</td>
<td align="left" valign="top">Male</td>
<td/>
<td align="center" valign="top">34.4&#x2009;&#x00B1;&#x2009;8.8</td>
<td align="center" valign="top">0.031<sup>&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Female</td>
<td/>
<td align="center" valign="top">35.0&#x2009;&#x00B1;&#x2009;8.5</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Status</td>
<td align="left" valign="top">Single<sup>a</sup></td>
<td/>
<td align="center" valign="top">36.6&#x2009;&#x00B1;&#x2009;9.4</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A; ab,ac</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Married<sup>b</sup></td>
<td/>
<td align="center" valign="top">34.5&#x2009;&#x00B1;&#x2009;8.6</td>
<td/>
</tr>
<tr>
<td/>
<td align="left" valign="top">Widowed/divorced/<sup>c</sup></td>
<td/>
<td align="center" valign="top">34.1&#x2009;&#x00B1;&#x2009;7.7</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Education level</td>
<td align="left" valign="top">Elementary school or lower<sup>a</sup></td>
<td/>
<td align="center" valign="top">33.9&#x2009;&#x00B1;&#x2009;8.7</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;ab,ac</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Secondary school<sup>b</sup></td>
<td/>
<td align="center" valign="top">35.9&#x2009;&#x00B1;&#x2009;8.6</td>
<td/>
</tr>
<tr>
<td/>
<td align="left" valign="top">Bachelor degree or higher<sup>c</sup></td>
<td/>
<td align="center" valign="top">36.3&#x2009;&#x00B1;&#x2009;7.7</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Monthly income</td>
<td align="left" valign="top">&#x2264;250 US Dollars</td>
<td/>
<td align="center" valign="top">34.9&#x2009;&#x00B1;&#x2009;8.5</td>
<td align="center" valign="top">0.181</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E;250 US Dollars</td>
<td/>
<td align="center" valign="top">34.5&#x2009;&#x00B1;&#x2009;8.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Co-morbidity</td>
<td align="left" valign="top">Yes</td>
<td/>
<td align="center" valign="top">34.0&#x2009;&#x00B1;&#x2009;7.7</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td/>
<td align="center" valign="top">35.0&#x2009;&#x00B1;&#x2009;9.0</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Smoking cigarette</td>
<td align="left" valign="top">Yes</td>
<td/>
<td align="center" valign="top">33.5&#x2009;&#x00B1;&#x2009;8.3</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td/>
<td align="center" valign="top">35.0&#x2009;&#x00B1;&#x2009;8.7</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Alcohol consumption</td>
<td align="left" valign="top">Yes</td>
<td/>
<td align="center" valign="top">33.6&#x2009;&#x00B1;&#x2009;8.1</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td/>
<td align="center" valign="top">35.2&#x2009;&#x00B1;&#x2009;8.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Acting as a health volunteer</td>
<td align="left" valign="top">Yes</td>
<td/>
<td align="center" valign="top">34.9&#x2009;&#x00B1;&#x2009;7.9</td>
<td align="center" valign="top">0.472</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td/>
<td align="center" valign="top">34.7&#x2009;&#x00B1;&#x2009;8.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Agricultural area</td>
<td align="left" valign="top">&#x2264; 4 acres</td>
<td/>
<td align="center" valign="top">34.2&#x2009;&#x00B1;&#x2009;9.1</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E; 4 acres</td>
<td/>
<td align="center" valign="top">35.6&#x2009;&#x00B1;&#x2009;7.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Planting status</td>
<td align="left" valign="top">Planting in own area</td>
<td/>
<td align="center" valign="top">35.7&#x2009;&#x00B1;&#x2009;8.7</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">Hiring</td>
<td/>
<td align="center" valign="top">31.3&#x2009;&#x00B1;&#x2009;7.6</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Working hours on farm</td>
<td align="left" valign="top">2&#x2013;4&#x2009;h./day</td>
<td/>
<td align="center" valign="top">36.4&#x2009;&#x00B1;&#x2009;9.0</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E;4&#x2009;h./day</td>
<td/>
<td align="center" valign="top">32.8&#x2009;&#x00B1;&#x2009;7.8</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Tasks on farm</td>
<td align="left" valign="top">Mixing pesticides</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">35.2&#x2009;+&#x2009;8.9</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">33.9&#x2009;&#x00B1;&#x2009;8.2</td>
<td/>
</tr>
<tr>
<td/>
<td align="left" valign="top">Spraying pesticides</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">35.4&#x2009;&#x00B1;&#x2009;9.0</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">33.6&#x2009;&#x00B1;&#x2009;7.9</td>
<td/>
</tr>
<tr>
<td/>
<td align="left" valign="top">Harvesting crop products</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">34.9&#x2009;&#x00B1;&#x2009;9.1</td>
<td align="center" valign="top">0.028<sup>&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">34.3&#x2009;&#x00B1;&#x2009;7.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Number of pesticides used</td>
<td align="left" valign="top">1 type</td>
<td/>
<td align="center" valign="top">34.5&#x2009;&#x00B1;&#x2009;8.4</td>
<td align="center" valign="top">0.277</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">&#x003E;1 type</td>
<td/>
<td align="center" valign="top">34.8&#x2009;&#x00B1;&#x2009;8.8</td>
<td/>
</tr>
<tr>
<td align="left" valign="top" rowspan="14">Sources of pesticide information</td>
<td align="left" valign="top">Neighbors</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">35.6&#x2009;&#x00B1;&#x2009;8.7</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">33.8&#x2009;&#x00B1;&#x2009;8.6</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Pesticide merchants</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">35.2&#x2009;&#x00B1;&#x2009;8.8</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">33.9&#x2009;&#x00B1;&#x2009;8.5</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Government officers</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">37.4&#x2009;&#x00B1;&#x2009;8.8</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">33.4&#x2009;&#x00B1;&#x2009;8.3</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Posters/brochures</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">36.0&#x2009;&#x00B1;&#x2009;7.2</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">34.5&#x2009;&#x00B1;&#x2009;8.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Online multimedia</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">35.5&#x2009;&#x00B1;&#x2009;7.2</td>
<td align="center" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">34.5&#x2009;&#x00B1;&#x2009;9.1</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Radio</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">35.1&#x2009;&#x00B1;&#x2009;7.2</td>
<td align="center" valign="top">0.176</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">34.7&#x2009;&#x00B1;&#x2009;8.9</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">Television</td>
<td align="left" valign="top">Yes</td>
<td align="center" valign="top">34.2&#x2009;&#x00B1;&#x2009;6.2</td>
<td align="center" valign="top">0.052</td>
</tr>
<tr>
<td/>
<td align="left" valign="top">No</td>
<td align="center" valign="top">34.9&#x2009;&#x00B1;&#x2009;9.2</td>
<td/>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><sup>&#x002A;</sup><italic>p</italic> value&#x2009;&#x003C;&#x2009;0.05; <sup>&#x002A;&#x002A;</sup><italic>p</italic> value&#x2009;&#x003C;&#x2009;0.01.</p>
<p>The different letters refer to significant differences.</p>
</table-wrap-foot>
</table-wrap>
<table-wrap position="float" id="tab5">
<label>Table 5</label>
<caption>
<p>Multiple linear regression analysis for investigating factors associated with HL among Thai farmers.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th rowspan="2"/>
<th align="center" valign="top" rowspan="2">Beta</th>
<th align="center" valign="top" rowspan="2">SE.</th>
<th align="center" valign="top" colspan="2">95% CI</th>
<th align="center" valign="top" rowspan="2"><italic>p</italic> value</th>
</tr>
<tr>
<th align="center" valign="top">Lower bound</th>
<th align="center" valign="top">Upper bound</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Age</td>
<td align="left" valign="top">0.020</td>
<td align="center" valign="top">0.013</td>
<td align="left" valign="top">&#x2212;0.005</td>
<td align="left" valign="top">0.046</td>
<td align="left" valign="top">0.118</td>
</tr>
<tr>
<td align="left" valign="top">Gender</td>
<td align="left" valign="top">&#x2212;0.698</td>
<td align="center" valign="top">0.284</td>
<td align="left" valign="top">&#x2212;1.255</td>
<td align="left" valign="top">&#x2212;0.141</td>
<td align="left" valign="top">0.014<sup>&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Region</td>
<td align="left" valign="top">1.503</td>
<td align="center" valign="top">0.149</td>
<td align="left" valign="top">1.210</td>
<td align="left" valign="top">1.796</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Marital status</td>
<td align="left" valign="top">&#x2212;0.964</td>
<td align="center" valign="top">0.262</td>
<td align="left" valign="top">&#x2212;1.479</td>
<td align="left" valign="top">&#x2212;0.450</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Education level</td>
<td align="left" valign="top">0.602</td>
<td align="center" valign="top">0.218</td>
<td align="left" valign="top">0.175</td>
<td align="left" valign="top">1.029</td>
<td align="left" valign="top">0.006<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Co-morbidity</td>
<td align="left" valign="top">&#x2212;0.791</td>
<td align="center" valign="top">0.273</td>
<td align="left" valign="top">&#x2212;1.326</td>
<td align="left" valign="top">&#x2212;0.256</td>
<td align="left" valign="top">0.004<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Number of family members</td>
<td align="left" valign="top">&#x2212;0.345</td>
<td align="center" valign="top">0.071</td>
<td align="left" valign="top">&#x2212;0.484</td>
<td align="left" valign="top">&#x2212;0.205</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Smoking cigarette</td>
<td align="left" valign="top">&#x2212;0.374</td>
<td align="center" valign="top">0.352</td>
<td align="left" valign="top">&#x2212;1.065</td>
<td align="left" valign="top">0.317</td>
<td align="left" valign="top">0.288</td>
</tr>
<tr>
<td align="left" valign="top">Alcohol consumption</td>
<td align="left" valign="top">&#x2212;0.547</td>
<td align="center" valign="top">0.300</td>
<td align="left" valign="top">&#x2212;1.134</td>
<td align="left" valign="top">0.041</td>
<td align="left" valign="top">0.068</td>
</tr>
<tr>
<td align="left" valign="top">Planting status</td>
<td align="left" valign="top">&#x2212;3.125</td>
<td align="center" valign="top">0.320</td>
<td align="left" valign="top">&#x2212;3.752</td>
<td align="left" valign="top">&#x2212;2.498</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Agricultural area</td>
<td align="left" valign="top">0.053</td>
<td align="center" valign="top">0.267</td>
<td align="left" valign="top">&#x2212;0.470</td>
<td align="left" valign="top">0.576</td>
<td align="left" valign="top">0.842</td>
</tr>
<tr>
<td align="left" valign="top">Working hours on farm</td>
<td align="left" valign="top">&#x2212;2.451</td>
<td align="center" valign="top">0.261</td>
<td align="left" valign="top">&#x2212;2.964</td>
<td align="left" valign="top">&#x2212;1.939</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Mixing pesticides</td>
<td align="left" valign="top">0.075</td>
<td align="center" valign="top">0.393</td>
<td align="left" valign="top">&#x2212;0.695</td>
<td align="left" valign="top">0.845</td>
<td align="left" valign="top">0.848</td>
</tr>
<tr>
<td align="left" valign="top">Spraying pesticides</td>
<td align="left" valign="top">2.449</td>
<td align="center" valign="top">0.389</td>
<td align="left" valign="top">1.686</td>
<td align="left" valign="top">3.211</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Harvesting crops</td>
<td align="left" valign="top">0.868</td>
<td align="center" valign="top">0.275</td>
<td align="left" valign="top">0.329</td>
<td align="left" valign="top">1.407</td>
<td align="left" valign="top">0.002<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Pesticide use of more than 1 type</td>
<td align="left" valign="top">&#x2212;1.502</td>
<td align="center" valign="top">0.326</td>
<td align="left" valign="top">&#x2212;2.142</td>
<td align="left" valign="top">&#x2212;0.862</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Pesticide information-Government officers</td>
<td align="left" valign="top">2.009</td>
<td align="center" valign="top">0.269</td>
<td align="left" valign="top">1.482</td>
<td align="left" valign="top">2.537</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Pesticide information-Posters/brochures</td>
<td align="left" valign="top">1.465</td>
<td align="center" valign="top">0.326</td>
<td align="left" valign="top">0.826</td>
<td align="left" valign="top">2.103</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Pesticide information-Online multimedia</td>
<td align="left" valign="top">0.969</td>
<td align="center" valign="top">0.292</td>
<td align="left" valign="top">0.396</td>
<td align="left" valign="top">1.542</td>
<td align="left" valign="top">0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Pesticide information-Neighbors</td>
<td align="left" valign="top">0.949</td>
<td align="center" valign="top">0.246</td>
<td align="left" valign="top">0.467</td>
<td align="left" valign="top">1.432</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">Pesticide information-Pesticide merchants</td>
<td align="left" valign="top">0.424</td>
<td align="center" valign="top">0.256</td>
<td align="left" valign="top">&#x2212;0.077</td>
<td align="left" valign="top">0.926</td>
<td align="left" valign="top">0.097</td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Hat</td>
<td align="left" valign="top">1.302</td>
<td align="center" valign="top">0.203</td>
<td align="left" valign="top">0.903</td>
<td align="left" valign="top">1.700</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Goggles</td>
<td align="left" valign="top">0.942</td>
<td align="center" valign="top">0.142</td>
<td align="left" valign="top">0.663</td>
<td align="left" valign="top">1.221</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Rubber apron</td>
<td align="left" valign="top">0.487</td>
<td align="center" valign="top">0.110</td>
<td align="left" valign="top">0.270</td>
<td align="left" valign="top">0.703</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Long-sleeved shirt</td>
<td align="left" valign="top">0.709</td>
<td align="center" valign="top">0.196</td>
<td align="left" valign="top">0.325</td>
<td align="left" valign="top">1.094</td>
<td align="left" valign="top">&#x003C;0.001<sup>&#x002A;&#x002A;</sup></td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Long-sleeved trousers</td>
<td align="left" valign="top">&#x2212;0.115</td>
<td align="center" valign="top">0.283</td>
<td align="left" valign="top">&#x2212;0.670</td>
<td align="left" valign="top">0.440</td>
<td align="left" valign="top">0.685</td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Boots</td>
<td align="left" valign="top">0.025</td>
<td align="center" valign="top">0.268</td>
<td align="left" valign="top">&#x2212;0.499</td>
<td align="left" valign="top">0.550</td>
<td align="left" valign="top">0.925</td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Mask</td>
<td align="left" valign="top">&#x2212;0.260</td>
<td align="center" valign="top">0.226</td>
<td align="left" valign="top">&#x2212;0.703</td>
<td align="left" valign="top">0.185</td>
<td align="left" valign="top">0.250</td>
</tr>
<tr>
<td align="left" valign="top">PPE use-Gloves</td>
<td align="left" valign="top">&#x2212;0.269</td>
<td align="center" valign="top">0.200</td>
<td align="left" valign="top">&#x2212;0.662</td>
<td align="left" valign="top">0.123</td>
<td align="left" valign="top">0.179</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><sup>&#x002A;</sup><italic>p</italic> value&#x2009;&#x003C;&#x2009;0.05; <sup>&#x002A;&#x002A;</sup><italic>p</italic> value&#x2009;&#x003C;&#x2009;0.01.</p>
</table-wrap-foot>
</table-wrap>
<p>Multiple linear regression analysis found that socio-demographic factors associated with HL scores included gender, region, marital status, level of education, co-morbidity, and number of family member.</p>
<p>Agricultural factors that were associated with HL scores included planting status, working hours on the farm, spraying pesticides, harvesting crops, use of &#x003E;1 type of pesticide, access information from government officers, access information from posters/brochures, access information from online multimedia, and access information from neighbors.</p>
<p>Personal protective factors that were associated with HL scores included wearing a hat, wearing goggles, wearing a rubber apron, and wearing a long-sleeved shirt.</p>
</sec>
</sec>
<sec sec-type="discussion" id="sec16">
<label>4</label>
<title>Discussion</title>
<p>According to our findings, Thai farmers had a mean HL score of 34.7&#x2009;&#x00B1;&#x2009;8.7. When the HL was compared to other studies that used the same HLS-EU-Q47 for measuring general HL, the farmers&#x2019; HL scores in our results were comparable to those of farmers in a prior study conducted in northern Thailand, where the mean HL score was 34.98 (<xref ref-type="bibr" rid="ref17">17</xref>). A study by S&#x00F8;rensen et al. (<xref ref-type="bibr" rid="ref9">9</xref>) investigated HL in eight European countries, and found the average HL scores were 31.95&#x2009;&#x00B1;&#x2009;7.63 in Austria, 30.50&#x2009;&#x00B1;&#x2009;9.17 in Bulgaria, 34.49&#x2009;&#x00B1;&#x2009;7.87 in Germany, 33.57&#x2009;&#x00B1;&#x2009;8.48 in Greece, 35.16&#x2009;&#x00B1;&#x2009;7.79 in Ireland, 37.06&#x2009;&#x00B1;&#x2009;6.40 in Netherlands, 34.45&#x2009;&#x00B1;&#x2009;7.98 in Poland, and 32.88&#x2009;&#x00B1;&#x2009;6.10 in Poland. A study by Duong et al. (<xref ref-type="bibr" rid="ref8">8</xref>) also investigated HL in six Asian countries, and found the average HL scores were 31.4&#x2009;&#x00B1;&#x2009;5.8 in Indonesia, 31.6&#x2009;&#x00B1;&#x2009;9.3 in Kazakhstan, 32.9&#x2009;&#x00B1;&#x2009;7.2 in Malaysia, 31.3&#x2009;&#x00B1;&#x2009;8.7 in Myanmar, 34.4&#x2009;&#x00B1;&#x2009;6.6 in Taiwan, and 29.6&#x2009;&#x00B1;&#x2009;9.1 for Vietnam. However, these two investigations were conducted in general populations. As a consequence, the interpretation of the data might not be comparable. Considering with subdomains of HL, our revealed that Thai farmers obtained the lowest scores of HL in tow sub-domains: Sub-domain 2: process/appraise information relevant to health Disease prevention and Sub-domain 6: disease prevention. These findings suggest that the farmers had low ability to interpret and evaluate information on risk factors for health. Therefore, it is crucial for the government and relevant organizations to prioritize evidence-based strategies and interventions aimed at improving farmers&#x2019; ability to interpret and evaluate information regarding health risk factors, particularly those associated with pesticide use.</p>
<p>Socio-demographic factors were crucial in relation to HL. According to our findings, socio-demographic factors that were related to the HL scores of farmers included gender, marital status, education level, co-morbidity, and family members. Farmers who were female, single, had a high level of education, had a small size of family members, and had no co-morbid conditions were likely to have a high level of HL.Our findings were consistent with a study by Chakraverty et al. (<xref ref-type="bibr" rid="ref27">27</xref>) which found clear evidence that women typically had a higher level of HL than men. They also mentioned that future research should consider men and women separately to ensure reliable results. A study by Sun et al. (<xref ref-type="bibr" rid="ref28">28</xref>) identified gender differences in factors associated with the HL in older patients with chronic diseases. They suggested that HL in men was associated with education background, number of dependents, monthly income, duration of chronic disease, and self-efficacy; while HL in women was associated with age, education background, monthly income, duration and treatment of chronic diseases.</p>
<p>Considering education level, our results were also in line with a study by Jansen et al. (<xref ref-type="bibr" rid="ref29">29</xref>) which suggested that attainment of higher levels of education was associated with higher scores of HL in aspects of appraisal of health information and the healthcare system. People with low levels of education had difficulty understanding and assessing health-related information. As a result, they were unable to successfully communicate with the health care system. On the other hand, people with high education found it easier to access, comprehend, and assess knowledge of health&#x2013;related issues (<xref ref-type="bibr" rid="ref30">30</xref>, <xref ref-type="bibr" rid="ref31">31</xref>).Walters et al. (<xref ref-type="bibr" rid="ref32">32</xref>) suggested that educational interventions could enhance HL and health-promoting behaviors. Face-to-face education and non-print media (such as video, images, etc.) were the most effective ways to transfer health messages to people with low levels of HL (<xref ref-type="bibr" rid="ref33">33</xref>). The government, media, and relevant organizations should collaborate effectively to provide HL services and focus on fairness of health education (<xref ref-type="bibr" rid="ref34">34</xref>).</p>
<p>Regarding marital status, our findings found that farmers who were single or married had higher HL scores than widows or divorcees. It is possible that individuals who were widowed or divorced had a lack of motivation to attend to things related to health education due to psychological, spiritual, and economical issues (<xref ref-type="bibr" rid="ref35">35</xref>). Another possibility is that other family members may support and compensate individuals to achieve health-related tasks (<xref ref-type="bibr" rid="ref36">36</xref>, <xref ref-type="bibr" rid="ref37">37</xref>). Co-morbid conditions were also associated with HL in both general populations and patient groups (<xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref38">38</xref>). Therefore, our findings suggested that in order to improve the HL of farmers, target populations should be prioritized when it comes to strategies and interventions, specifically including men, those who are widowed or divorced, those with low levels of education, and those who have co-morbidities.</p>
<p>Farmers&#x2019; residential region also affected their level of HL. Our findings found that farmers in the North region of Thailand had the lowest level of HL, while those in the North-East had the highest HL. Importantly, farmers in the North region had the highest frequency of limited HL (75.8%). It is possible that this was because the majority of farmers in the North region (89.2%) only had completed an elementary school or lower, while in the North-East there was the largest percentage of farmers with a bachelor degrees or above (7.2%) when compared to other regions. Therefore, strategies and interventions should be focused on the farming population in the North region to improve health equity in Thailand.</p>
<p>Regarding agricultural aspects, our results found that farmers who planted on their own farm, worked on the farm 2&#x2013;4&#x2009;h/day, sprayed pesticides, harvested crops, and applied only one type of pesticide on their farm were more likely to have a higher level of HL. These findings were consistent with a study by Montgomery et al. (<xref ref-type="bibr" rid="ref17">17</xref>) which mentioned that length of time farming, and no chemical use in farming were associated with high HL in farmers. One previous piece of research in Thailand also suggested that functional literacy was significantly associated with pesticide use behaviors among sweet corn farmers (<xref ref-type="bibr" rid="ref16">16</xref>). Our results also found that farmers who got pesticide information from government officers, posters/brochures, online multimedia, and neighbors were also likely to have high levels of HL. Interestingly, the information from government officers showed the strongest association with HL, followed by posters/brochures. In contrast, the study by Li et al. (<xref ref-type="bibr" rid="ref3">3</xref>) mentioned that the four main sources of health information for older adults in China were healthcare practitioners, neighbors, newspapers, and television. It is possible that the different population groups might affect their health information sources. It is also possible that sources of health information for various population groups varied depending on their ages and region of residence. The findings from our study suggested that in-person education from government officers and posters/brochures were the most efficient means of conveying health-related information to farmers. Improvement of HL through both interpersonal and mass communication means should be simultaneously implemented (<xref ref-type="bibr" rid="ref3">3</xref>).</p>
<p>Regarding personal protective behavior, PPE use during pesticide application was also a crucial factor related to the HL of farmers. Our results found that farmers who wore a hat, goggles, a rubber apron, and a long-sleeved shirt were likely to have high HL. Available previous studies clearly mention that wearing of PPE and prevention practices against pesticide exposure were the main factors influencing the HL of farmers (<xref ref-type="bibr" rid="ref39">39</xref>, <xref ref-type="bibr" rid="ref40">40</xref>). A systematic review by Sapbamrer and Thammachai (<xref ref-type="bibr" rid="ref41">41</xref>) concluded that the most basic PPE worn among pesticide handlers in all regions of the world was a long-sleeved shirt (66.1%), long-sleeved trousers (71.1%), and a hat (47.3%), while the lowest basic PPE worn was an apron (8.6%), goggles (24.3%), gloves (40.5%), boots (42.3%), and a mask (43.2%). In Thailand, farmers usually wore everyday available clothing, a fabric hat, and fabric mask to protect themselves from exposure to pesticides. However, they hardly ever used goggles, respirators, and rubber aprons during pesticide application. The main reason included tropical climatic weather conditions, discomfort while working, poverty, lack of availability of PPE, and the expense of PPE (<xref ref-type="bibr" rid="ref25">25</xref>). A systematic review by Sapbamrer and Thammachai (<xref ref-type="bibr" rid="ref41">41</xref>) also mentioned that access to extension services, training programs, information about pesticides, and farm organization are all crucial determinants associated with PPE use. Education interventions to improve safety and HL for farmers with a variety of approaches that take into account cultural aspects, individual factors, and community involvement had the greatest outcomes with regard to changing the behavior of farmers (<xref ref-type="bibr" rid="ref42">42</xref>, <xref ref-type="bibr" rid="ref43">43</xref>). Several approaches have been used in educational interventions such as training, movies, newsletters, community fairs, games, and community engagement in program design (<xref ref-type="bibr" rid="ref42">42</xref>). It is evident that a life-long education program regarding safety and health-related concerns with several approaches could enhance the HL of farmers and sustainably improve pesticide safety behavior.</p>
<p>Previous research conducted in Thailand highlighted a significant gap in the knowledge of alternative pest management and modern agricultural technology among Thai farmers, due to their limited literacy levels (<xref ref-type="bibr" rid="ref19">19</xref>, <xref ref-type="bibr" rid="ref20">20</xref>, <xref ref-type="bibr" rid="ref25">25</xref>). Integrating biological control methods is crucial within the framework of integrated pest management (IPM), aimed at reducing use of pesticides and chemicals. The adoption of IPM not only yields immediate benefits but also contributes to developmental benefits across technical, social, and political domains (<xref ref-type="bibr" rid="ref44">44</xref>). However, the adoption and implementation of IPM and biological control worldwide were rather slow (<xref ref-type="bibr" rid="ref45">45</xref>). Furthermore, a meta-analysis conducted by Tamburini et al. (<xref ref-type="bibr" rid="ref46">46</xref>) strongly suggests that agricultural diversification practices can significantly enhance various ecosystem such as biodiversity, pollination, pest control, nutrient cycling, soil fertility, and water regulation, all while maintaining crop yields. Consequently, there is an urgent need for participatory training programs to promote the adoption of IPM and agricultural diversification practices, fostering the sustainable development of agro-ecosystems (<xref ref-type="bibr" rid="ref44">44</xref>).</p>
<p>The data for the present study were gathered from 31 provinces, accounting for 40.3% of all provinces, and from four main regions of Thailand. As a result, the findings can be generalized to all Thai farmers nationwide. Additionally, the findings regarding HL can be provided visually in regional hot spots, and further target actions appropriately to reduce limited HL and health disparities. However, limitations to our study exist. First, the data on pesticides used could only be collected in terms of the types of pesticides, not their active components or common names, due to the low literacy levels of the farmers. Second, recall-bias for agricultural information over the past 3&#x2009;months might have occurred, limiting accuracy of data. Third, the presence of language and cultural disparities across various regions in Thailand may serve as confounding variables that impact the interpretation of study findings. Fourth, a cross-sectional study design cannot explore relationships between cause and effect. These limitations should be taken into account for further investigations.</p>
</sec>
<sec sec-type="conclusions" id="sec17">
<label>5</label>
<title>Conclusion</title>
<p>The findings of this study indicate that farmers in the North region of Thailand had the highest frequency of limited HL. Socio-demographic factors associated with the HL of farmers included gender, marital status, education level, co-morbidity, and the number of family members. Agricultural factors associated with the HL of farmers included planting status, working hours on the farm, task of the farm, number of pesticides used, and PPE use during pesticide application. Therefore, the recommendations from our study are that strategies and interventions to enhance HL in farmers should be focused on the target populations which include men, widows or divorcees, those with low levels of education, those who have co-morbidities, and those who apply pesticides of more than 1 type, and improper PPE use. The North region of Thailand should be the primary emphasis of the target area to improve health equity in Thailand. The most effective way to transfer knowledge about safety and health-related issues to farmers is via a lifelong education program using several approaches, along with posters and brochures. Improvements in HL and health equity need to be urgently addressed by the government and relevant organizations to develop and launch appropriate health promotion strategies and interventions. Importantly, the government and relevant organizations need to focus on evidence-based strategies and interventions aimed at improving farmers&#x2019; ability to interpret and evaluate information regarding health risk factors, particularly those associated with pesticide use. Interventions aimed at enhancing farmers&#x2019; capacity to interpret and evaluate information concerning the safe uses of pesticides and preventive measures from pesticides are urgently needed. These efforts could enhance the HL of farmers and improve pesticide safety behavior sustainably.</p>
<p>Further research involving longitudinal study design could provide valuable insights into addressing these issues. Additionally, intervention studies aimed at enhancing farmers&#x2019; HL, particularly their ability to interpret and evaluate risk factors information for health are warranted. Specifically within the context of pesticides, interventions focusing on enhancing farmers&#x2019; capacity to interpret and evaluate information concerning the safe uses of pesticides and preventive measures from pesticides are also warranted. Prioritizing intervention studies targeting the farming population in the North region could contribute significantly to improving health equity in Thailand.</p>
</sec>
<sec sec-type="data-availability" id="sec18">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec sec-type="ethics-statement" id="sec19">
<title>Ethics statement</title>
<p>The studies involving humans were approved by the Research Ethics Committee of the Faculty of Medicine, Chiang Mai University, Thailand (No. 419/2022). The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study.</p>
</sec>
<sec sec-type="author-contributions" id="sec20">
<title>Author contributions</title>
<p>RS: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing &#x2013; original draft, Writing &#x2013; review &#x0026; editing. NaS: Formal Analysis, Investigation, Methodology, Writing &#x2013; review &#x0026; editing. ST: Investigation, Methodology, Writing &#x2013; review &#x0026; editing. EC: Investigation, Methodology, Writing &#x2013; review &#x0026; editing. CS: Investigation, Methodology, Writing &#x2013; review &#x0026; editing. AL-L: Investigation, Methodology, Writing &#x2013; review &#x0026; editing. PT: Investigation, Methodology, Writing &#x2013; review &#x0026; editing. AT: Formal Analysis, Writing &#x2013; review &#x0026; editing. BS: Formal Analysis, Writing &#x2013; review &#x0026; editing. NoS: Formal Analysis, Writing &#x2013; review &#x0026; editing. AK: Formal Analysis, Writing &#x2013; review &#x0026; editing. JP: Formal Analysis, Writing &#x2013; review &#x0026; editing. TS: Formal Analysis, Writing &#x2013; review &#x0026; editing.</p>
</sec>
</body>
<back>
<sec sec-type="funding-information" id="sec21">
<title>Funding</title>
<p>The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This study was supported by the Faculty of Medicine, Chiang Mai University (Grant Nos. 65&#x2013;66 and 114&#x2013;66).</p>
</sec>
<ack>
<p>The authors wish to thank the Faculty of Medicine, Chiang Mai University, Thailand, for editing English and other supports.</p>
</ack>
<sec sec-type="COI-statement" id="sec22">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="sec100" sec-type="disclaimer">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
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