Scenario-based assessment of emergency management of urban infectious disease outbreaks

Infectious diseases pose a severe threat to human health and are accompanied by significant economic losses. Studies of urban outbreaks of infectious diseases are diverse. However, previous studies have neglected the identification of critical events and the evaluation of scenario-based modeling of urban infectious disease outbreak emergency management mechanisms. In this paper, we aim to conduct an empirical analysis and scenario extrapolation using a questionnaire survey of 18 experts, based on the CIA-ISM method and scenario theory, to identify the key factors influencing urban infectious disease outbreaks. Subsequently, we evaluate the effectiveness of urban infectious disease outbreak emergency management mechanisms. Finally, we compare and verify the actual situation of COVID-19 in China, drawing the following conclusions and recommendations. (1) The scenario-based urban infectious disease emergency management model can effectively replicate the development of urban infectious diseases. (2) The establishment of an emergency command center and the isolation and observation of individuals exposed to infectious diseases are crucial factors in the emergency management of urban outbreaks of infectious disease.

media and traditional media (3).These social issues also pose significant challenges to national and city emergency management (4).SRAS, H 1 N 1 , and Ebola outbreaks have provided valuable lessons in managing infectious diseases.Lin et al. summarized emergency management procedures in radiology departments during the SARS outbreak (5).Fraser and Donnelly assessed the severity of H 1 N 1 and emphasized the need for effective health measures to combat infectious diseases (6).Brooks et al. emphasized the importance of establishing a functional incident management system (IMS) during the Ebola virus disease outbreak in West Africa (7).Chavez, Long, et al. underscored the crucial role of physicians in controlling emerging infectious diseases in cities (8).In the early stages of a new infectious disease outbreak, it is essential to follow available guidelines and strictly adhere to infection control principles (9).Zhang and Zhou encourage maintaining social distance and implementing measures based on population characteristics after a new infectious disease outbreak (10).Glass and Glass proposed tailored social distancing measures for young people and children in infectious disease contexts (11).In the event of a shortage of public health facilities and medical resources, hospitals must allocate resources equitably based on the best health outcomes, guided by local government or professional bodies (12).Societal-level measures like social isolation, blockades, border closures, and human tracking can help control COVID-19 transmission (13-15).Scenarios are dynamic model forms of events that enable changing outcomes by controlling event likelihood, providing decision-makers with tools to synthesize trends and events into manageable options.They add value to traditional planning techniques (16).Previous studies overlooked the interaction between emergency management elements in reducing urban infectious disease impacts, neglecting scenario-based assessments of urban infectious disease outbreaks, despite their applicability to novel infectious diseases.
This paper aims to address two main questions: What are the relationships between key events in urban outbreak emergency management of infectious diseases, and how do these interactions impact the effectiveness of urban infectious disease emergency management across different scenarios?Additionally, how can practical and effective suggestions be provided for emergency management decision-makers?To tackle these issues, key events in urban infectious disease outbreaks were identified.The paper employs the CIA, ISM, and Delphi methods to establish a scenariobased assessment model for urban infectious disease emergency management.Subsequently, interactions were analyzed, and urban emergency management was simulated under various scenarios to assess the impact of emerging infectious diseases on economic loss, human casualties, disease control, and public trust.Finally, an evaluation of Wuhan, China's emergency management response to COVID-19, an urban emerging infectious disease, was conducted.The contributions of this paper compared to existing studies include: (1) Extraction of key events for emergency management of emerging urban infectious diseases and clarification of interrelationships among actual events related to urban infectious diseases.(2) Proposal of an integrated model for scenario analysis by combining the CIA, ISM, and Delphi methods.(3) The model's ability to evaluate the effectiveness of urban infectious disease emergency management and provide proven recommendations for decision-makers through scenario analysis and extrapolation of urban infectious disease development.

Literature review
Research on emergency management of infectious diseases has primarily focused on preparedness, transmission modeling, economic loss assessment, and the societal impact of outbreaks.Brouqui et al. developed an infectious disease control framework for managing outbreaks (17).Wong et al. examined emergency preparedness for SARS and avian influenza in Hong Kong and proposed new public health management measures (18).The CDC has implemented measures to address EBOV spread, including monitoring travelers from affected areas and assessing hospital capacities (19).Effective collaboration among medical personnel and sufficient medical resources are crucial in emergency management.Therefore, it is essential to provide a safe working environment, adequate food, rest, and psychological support for healthcare workers globally (20).Lam et al. analyzed the challenges of guideline implementation and emergency management in acute care settings (21).Huang et al. outlined emergency management and infection control strategies in the radiology department, resulting in zero COVID-19 infections among staff (22).
In developing infectious disease transmission models, Kucharski et al. used SARS-CoV-2 transmission data from Wuhan in 2019 to show that regional closures reduce transmission, but delayed closures may lead to widespread outbreaks (23).Wu and Leung utilized exported case data to model outbreaks in major Chinese cities, indicating inevitable global outbreaks in urban centers (24).Razavi-Shearer et al. estimated regional HBV prevalence using a dynamic transmission model in the context of childhood vaccination (25).Chang et al. simulated SARS-CoV-2 spread in 10 United States cities, highlighting mobility's role in increased infection rates and economic losses (26).Musa et al. modeled COVID-19 transmission and mortality, suggesting that a combination of social distancing and vaccination could reduce mortality in South America (27).
COVID-19 poses significant threats to economic development, social systems, and human life, instigating concerns about potential economic crises or recessions.Kim and Loayza argue that, compared to high-income countries, the benefit governments in low-income nations gain from not intervening in epidemic prevention measures is marginal (28).Maria and Zaid Alsafi provide an overview of COVID-19's impact on various aspects of the global economy (1,29).
The array of social crises resulting from infectious diseases should not be underestimated, with panic being a prevalent psychological response to new outbreaks.How governments assess and address public panic can significantly influence the effectiveness of infectious disease emergency management mechanisms (30).A panic-induced rush for supplies is highly probable, underscoring the importance of maintaining adequate supplies during significant public health events (31,32).Wang et al. utilized the DASS-21 model to evaluate the psychological status of 1738 individuals in China, emphasizing the need to focus on case escalation, promote proper coping mechanisms, and enhance personal protection in response to COVID-19 (33).Rumors often stem from panic, hindering emergency management efforts by spreading misinformation (34).Hui et al. developed a rumor propagation model based on infectious disease models, suggesting effective strategies to counteract the spread of COVID-19 rumors (35).Ning et al. underscore the importance of authoritative announcements in dispelling rumors and mitigating their impact during the early months of the COVID-19 outbreak in China (36).Individuals seek to minimize losses and avert catastrophic consequences through pivotal decisions (37).
While most studies have examined the impact of individual events or factors, emergency management responses to a single factor may prove less effective when multiple events or factors interact.To ensure reliable and effective emergency management of urban COVID-19 outbreaks, management strategies must consider the cross-influences among various factors.The scenario-based approach assesses interactions between critical events within a specified timeframe (38), enhancing managers' understanding of the factors involved in developing COVID-19 contingency plans and the response measures required.When integrated with other predictive models, scenario models offer flexible approaches to address uncertainty.This paper examines potential future trends in urban infectious disease outbreaks, identifies key factors, and proposes optimal decisions.
3 Research methodology

Basis of the scenario approach
The scenario-based emergency management model for urban outbreaks of infectious diseases combines the Delphi method, the cross-influence approach (CIA), and the Interpretative Structural Model (ISM).Its purpose is to analyze scenarios and interpret the progression of urban infectious disease outbreaks.The Delphi method and CIA enable the analysis of factors influencing urban outbreaks.CIA identifies relationships between events affecting outcomes, enhancing the stability of identified events.However, using CIA requires presenting a series of interrelated future events.A team of experts conducts a Delphi process to predict event occurrence based on inputs, jointly assessing cross-impacts.

Creation of event set
Creating the COVID-19 event set is based on observing and studying historical infectious disease cases.Addressing significant health events necessitates considering technical and social factors and obtaining input from experts with diverse experiences and perspectives.This approach aims to identify critical factors and relationships, ensuring decision-making rationality, internal consistency, and usefulness.A comprehensive set of 32 relevant events was selected and categorized into three types.Initial events (IC i ): These events occur or not before infectious disease outbreaks.They may reflect emergency management of urban outbreaks, significantly impacting disease development.Experts subjectively estimate initial event probabilities at 0.5.If an event with a probability below 0.5 is anticipated, experts reassess other events' probabilities.Dynamic events (DE i ) encompass post-epidemic occurrences, primarily consisting of government emergency management measures and events triggering secondary disasters.These events are assigned a probability of occurrence of 0. Outcome event (OE i ) encompasses various consequences that may arise from an infectious disease event, such as casualties and property damage.The probability of an outcome event is determined accurately at the end of the period, with an initial probability also set to 0.5.OE 1 : Economic loss: GDP loss caused by infectious diseases.OE 2 : Personnel Casualties: a certain number of infectious disease patients die.OE 3 : Infectious disease is controlled: The city's Infectious disease is controlled in a phased manner, and the number of sick people gradually decreases without spreading to other cities or regions.OE 4 : Public trust: The public has a high level of trust in the local government after the epidemic and continues cooperating with the government in its actions.
Expert estimates of the relationship between the three-event sets (initial conditions, dynamic events, and outcome events) were sought.

Scenario analysis
Eighteen experts in emergency management and frontline rescue were invited to participate in the expert panel.They assessed whether each of the three event sets occurred and estimated the probability of other events happening.Due to the diverse nature of each event, the panel had to make 478 causality estimates, as illustrated in Figure 1.
Events within a set are interconnected.However, in the Delphi method, the occurrence or non-occurrence of one event does not impact others in the set.Therefore, we integrated the CIA into the ISM and used it to obtain the three event sets of COVID-19 as input for the ISM.The most critical aspect of CIA-ISM is "structural modeling." The ISM approach provides a solid mathematical foundation for establishing linear relationships between critical events and their influencing factors.Initially, experts estimate the relationships and probabilities between events.Then, a model is constructed to reflect the complex relationships over time, with the flexibility to receive feedback at different stages, enabling experts to adjust inputs as needed.
The occurrence probability of event i, influenced by event j, follows the rule outlined in Table 1, known as the scoring table.A valid factor metric between i and j is established when at least two-thirds of the individual interaction estimates fall within an interval in the scoring table.The resulting adjacency matrix serves as input for the CIA, where cells represent the linear influence factor of event i on j, denoted as R ij .Diagonal cells indicate the total probability.Using this binary matrix, we can forecast scenarios by assuming event i's occurrence (or non-occurrence).

Cross-impact analysis
In Table 1, a mathematical "+" denotes event facilitation, while a mathematical "-" signifies suppression.These symbols only show the impact's direction and do not denote magnitude.Equations 1, 2 represents the cross-influence factor and event occurrence probability.
( ) where G i is the sum of the effects of all possible external events on the event i that are not explicitly represented in the n events included in the model.To obtain a numerical estimate of the total variability in the matrix, we examined the following linear sum of the cross-impact factorΣ|C ij |.Calculate the relative fraction or percentage of impact due to each type of event.
|Dynamic event impact|/|Total impact| = 0.615771461.|initial event impact|/|total impact| = 0.337109206.|External unspecified event impact|/|Total impact| = 0.21437264.Thus, unspecified events (external event impact) contribute to 21.44% of the overall impact, while dynamic events and initial conditions contribute 61.58 and 33.71%, respectively.In total, 78.56% of the impact in the model is attributed to explicit events.This suggests that the event set is relatively comprehensive, rendering the model feasible.
After deriving the cross-impact matrix, we delineate the strong relationships within the directed graph model by partitioning and extracting the matrix model.By employing the CIA-ISM method, we can illustrate the anticipated scenario using a directed graph.Table 2 outlines the direct and indirect effects of each event on the outcome events (cascade effects).The model suggests that event DE 1 may either positively impact favorable outcomes or negatively influence adverse outcomes.IC 6 , IC 8 , and IC 9 directly negatively impact DE 15 , indicating that government emergency response capacity, establishment of emergency command centers, and public trust can significantly decrease the likelihood of partial health care worker non-cooperation.Similarly, IC 2 , IC 7 , and DE 2 directly negatively influence DE 16 , signifying that enhancing infectious disease source detection capabilities, information disclosure, and causation identification would markedly diminish the probability of partial public non-cooperation.
Among all emergency response efforts, the establishment of an emergency command center (DE 8 ) has a direct and significant impact on reducing economic losses (OE 1 ), controlling infectious diseases (OE 3 ), and increasing public trust (OE 4 ).Limiting the movement of people (DE 12 ) made a considerable contribution to increasing public trust (OE 4 ).Among all secondary-derived disasters, the spread of infectious diseases (DE 11 ) directly and significantly impacts human casualties (OE 2 ).
Analyzing outcome events can be enhanced by considering the direct impact of initial conditions and dynamic events on these specific outcomes, as shown in Tables 3-6.For instance, Table 3 demonstrates that the model anticipates leadership disagreement in releasing information, while partial public non-cooperation emerges as the primary precursor to potential economic loss.Conversely, establishing an emergency command center, evaluating infectious disease transmission capacity, and implementing a government contingency plan markedly diminish the probability of such an outcome.

10×4 10×18 18×4 17×18
Influence diagram of the number of three event sets and the number of estimates required.We enumerate the events that directly influence the outcome event, whether positively or negatively.Conversely, critical factors influencing the containment of infectious diseases and fostering public trust included establishing an emergency command center, identifying the causative agent, and limiting people's movement (see Tables 5, 6).Conversely, factors such as infection spread, public panic, and vaccine unavailability hindered these desired outcomes.Tables 3-6 present the key events influencing the occurrence or absence of each of the four outcomes.The values in Table 7 are calculated by summing the absolute positive impacts of C ij on the events.Table 8 displays the most significant events contributing to adverse outcomes.The weights presented indicate the cumulative adverse impact, represented by the sum of the absolute negative impacts of C ij on the events.

Incremental analysis
We conduct incremental analysis on the predicted scenarios to comprehend the relationships among different events.The primary approach involves analyzing the distribution of |C ij |.Non-zero |C ij | values are selected, and a histogram illustrating their frequency from zero to the maximum absolute value is plotted, as depicted in Figure 2.
Subsequently, we identify the value of |C ij | representing the highest k% of the distribution as the cut-off point for the directed graph.For instance, selecting 90 and 85% as the cut-off points results in the directed graph highlighting the top 10 and 15% impacts, as illustrated in Figures 3, 4. Lines connecting events of the same color denote positive impacts, while those connecting events of different colors signify negative impacts.The graph is directed, with the highest 85% of the distribution value determining its structure.At this analytical level, while all events are included, the logical sequence of events is not organized.To refine the model, additional |C ij | factors were integrated into the analysis, considering all |C ij | values greater than or equal to this threshold to establish the final model.At this stage, the |C ij | value of event i is utilized before or after the occurrence and non-occurrence of event j.The histogram of cross-influencing factors indicates that the limit value is |C ij | = 3.42 when extracting the most significant influence of the top 5%.Subsequently, the CIA-ISM output is displayed in Figure 4, with its adversarial plot depicted in Figure 5.If the value of |C ij | equals or surpasses the limit value, a direct connection from node j to node i is established.Identifying the most critical event in the event set through the limit value aids in comprehending the underlying logic of the particular influence path and scenario leading to that outcome, while also facilitating an understanding of the event sequence and its potential impact.

Sensitivity analysis
This paper aims to model the emergency management of urban infectious disease outbreaks, so the associated events are selected for sensitivity analysis.The impact of critical factors is tested by varying the initial probabilities.

Initial conditions analysis
Based on the preceding analysis, it is evident that IC 4 , 5 , 6 , and 8 are events pertinent to emergency management.Sensitivity analysis scrutinizes the outcomes of other events, particularly outcome events, by modifying the initial probabilities of these four events.We establish six scenarios to forecast occurrences where all four crucial events manifest, all fail to occur, and only one materializes.The initial probability of other events is set at 0.5.Utilizing formula (1, 2), we derive the probability of other events occurring across the six scenarios, as presented in Table 9. Economic loss (OE 1 ) is influenced by the initial events in the descending order of IC 6 , IC 5 , IC 8 , and IC 4 .The government's emergency response capability (IC 6 ) plays a pivotal role in mitigating economic loss.
The government must regularly update its contingency plan for urban infectious disease outbreaks (IC 5 ), assess medical resource reserves (IC 4 ), and promote public awareness of epidemic resistance.Among the four critical events, IC 4 significantly decreases casualties (OE 2 ).Therefore, it is crucial for priority hospitals and treatment facilities to maintain sufficient medical resource reserves (IC 4 ) and enhance government emergency response capacity (IC 6 ).A robust government emergency response plan (IC 5 ) is pivotal in bolstering public confidence and fostering public trust (OE 3 ).Collectively, these four initial conditions can greatly mitigate losses, underscoring the need for adequate emergency preparedness to address the human fatalities and economic ramifications associated with COVID-19.

Analysis of dynamic events
The analysis above indicates that dynamic events related to emergency management include DE 5 , 8 , 11 , 12 , and 14 .The impact of these pivotal events can be similarly assessed, as depicted in Tables 10,11.The establishment of an emergency command center (DE 8 ) significantly reduces economic losses (OE 1 ).Implementation of personnel isolation measures (DE 5 ) can also mitigate economic loss (OE 2 ).While individually, none of these six dynamic events critically affects the four outcome events, their combined effect can be substantial.Therefore, we explored several scenarios (S 6 , 7 , 8 , and 9 ). In

Scenario reasoning for emergency management of COVID-19 in Wuhan, China
Analyzing the epidemic's progression reveals the critical timeline of anti-epidemic events subsequent to the COVID-19 outbreak in Wuhan, detailed in Table 13.Initially, Wuhan Jinyintan Hospital faced shortages in essential resources for infectious disease control, including protective equipment such as medical gowns, masks, and goggles (39).In December 2019, Wuhan reported pneumonia cases attributed to a novel coronavirus strain, distinct from the 2003 SARS outbreak, prompting speculation about a new coronavirus variant (40).Consequently, IC 1 = IC 2 = IC 3 = 1, and IC 4 = 0. Despite advancements in infectious disease management, Wuhan hospitals' routine infection prevention measures proved insufficient for novel viruses (41).While Wuhan regularly conducted outbreak drills for common infectious diseases, these preparations lacked adequacy for highly transmissible viruses, undermining their response capabilities.Public self-protection measures were initially deficient, with limited access to clear guidance exacerbating the situation (42,43).Local governments struggled with public communication, lacking comprehensive plans for engagement, although public trust in government instructions remained intact.Given the novelty of the coronavirus, its initial emergence saw no available vaccine (44).To summarize, the initial event probabilities are IC 5 = IC 6 = IC 7 = IC 8 = IC 10 = 0 and IC 9 = 1.
Once dynamic events occur, they have a probability of 1.At the onset of the COVID-19 outbreak, numerous cases emerged both within and outside Hubei Province, with infections also reported in other countries.This situation led to varying degrees of panic among the population (45).Concurrently, a plethora of rumors circulated on the internet and social media platforms, disseminating However, mass production of the vaccine remains unfeasible in the short term (49), and sporadic instances occur where local authorities withhold information about the epidemic's status from the public (50).

Results of cross-impact analysis
The probabilities of events in the six scenarios are presented in Table 12, derived from the preceding formula.In accordance with the temporal order of key events, DE 8 = DE 12 = DE 5 = DE 14 = DE 11 = 1 was established, as illustrated in Table 14.Additionally, leveraging the timeline provided in Table 13, we inferred the epidemic spread scenario post-COVID-19 outbreak in Wuhan using seven steps (51), as depicted in Table 14.
To assess the model's accuracy, the predicted outcomes were juxtaposed with the actual COVID-19 situation in Wuhan.As of March 10, 2020, at 24:00, Hubei Province had reported a cumulative total of 67,773 confirmed cases, 49,056 recoveries, and 3,046 deaths.Following the initial onset of COVID-19, there was a notable surge in mortality and daily new cases, accompanied by a poor recovery rate, as depicted in Figures 6-8.
The probability of human casualties (OE 2 ) surged from 1.163% to nearly 9%, as illustrated in Figure 9.As Chikyu Wuhan intensified its anti-epidemic efforts, the COVID-19 mortality rate swiftly dropped from 9.026% on January 27 to 5.346% on January 28.In Wuhan, the number of new cases exhibited the initial signs of decline by 2.14, marking the beginning of a downturn in cumulative deaths, while the tally of recoveries continued to rise, as depicted in Figures 10-13.
Subsequent mortality rates continued to decrease and stabilized below 5%, indicating that the epidemic was largely under control by early March, as evidenced in the attached video.The projected trend aligns with the actual situation outlined in the statistical report.COVID-19 resulted in damages exceeding $1.1 trillion.Despite substantial donations and supplies raised by the government, they had minimal impact on offsetting the substantial losses.The probability of economic loss (OE 1 ) consistently hovered near 100% with minimal fluctuations, mirroring the actual scenario.Emergency response measures following the COVID-19 outbreak had limited success in mitigating economic losses, emphasizing the need for stronger focus on emergency preparedness.The Chinese government is lauded for its swift emergency response to the COVID-19 outbreak.The central government promptly dispatched medical personnel to affected regions within days of the outbreak.Various departments actively gathered and validated valuable data, while the National Health Commission promptly disseminated the latest updates to the public.The prompt dissemination of authoritative information alleviated public panic and anxiety to some extent, garnering praise domestically and internationally.Following COVID-19, the probability of public trust (OE 4 ) decreased to nearly 10%, reflecting the actual circumstances.Public trust notably surged after the government's swift relief measures.The government efficiently shaped public opinion and promptly disclosed outbreak information, markedly reducing social panic and enhancing public trust.The probability of public trust was highest upon the arrival of rescue teams and supplies in Wuhan, coupled with the prompt distribution of emergency medical supplies to those in need.The findings suggest that the government actively quelled public panic and fostered public trust, with the establishment of the emergency command center being pivotal.Nonetheless, in the initial scenario (step 0 ), the probabilities of both outcome events reached very high values, underscoring the substantial impact of the lack of emergency preparedness on outcomes resulting in severe losses.The simulation results better align with the actual scenario, as depicted in Figure 12.
The emergency response to the COVID-19 outbreak in Wuhan was swift and effective.However, weak emergency preparedness could still lead to significant casualties and substantial economic losses.Our simulation aims to create dynamic scenarios for potential urban infectious disease outbreaks.Developing scenario-based contingency plans for such outbreaks can assist decision-makers in analyzing potential scenarios during the COVID-19 pandemic and predicting the impact and consequences of various actions they may take.The simulation includes four scenarios: IC 4 = 1, IC 5 = IC 7 = 0; IC 5 = 1, IC 4 = IC 7 = 0; IC 7 = 1, IC 4 = IC 5 = 0; IC 4 = IC 7 = IC 5 = 1.The remaining parameters mirror those of the Wuhan COVID-19 outbreak.

Time Events
Dec 27, 2019 The hospital reported a case of unexplained pneumonia to the Jianghan District CDC.

Dec 30
The National Health and Wellness Commission was informed of this and immediately organized research and prompt action.

Jan 5
The World Health Organization informs about the cases of unexplained pneumonia in Wuhan.

Jan 7
Successful isolation of a novel coronavirus strain by the Chinese CDC.

Jan 9
The pathogen was initially determined to be a novel coronavirus.

Jan 10
The National Health and Wellness Commission shares information on the genome sequence of the new coronavirus with the World Health Organization.

Jan 15
Released the first version of the treatment, prevention and control protocol for pneumonia with novel coronavirus infection.

Jan 17
The National Health and Wellness Commission sent seven supervisory teams to localities to guide the prevention and control of the epidemic.

Jan 18
Release the second version of the treatment protocol for pneumonia with novel coronavirus infection.

Jan 19
Organized a high-level expert group on prevention and control to rush to Wuhan City for a field study on the prevention and control of the outbreak.Clarify that human-to-human transmission of the new coronavirus is occurring.Step Scenario Step The probabilities of four outcome events -human casualties, economic losses, disease control, and public trust under different scenarios -are illustrated in Figures 14-17, respectively.Figure 15 demonstrates that government communication capacity (IC 8 ) positively impacts reducing economic losses.However, recovering from significant economic losses caused by COVID-19 proves challenging.Figure 15 also highlights the critical roles of medical resource reserves (IC 4 ) and public self-protection capabilities (IC 7 ) in mitigating human casualties, alongside the positive effect of government contingency plans (IC 5 ).Factors such as public panic Cumulative deaths due to COVID-19 on January 30.

Conclusion
This paper convenes an expert panel of emergency management specialists and Wuhan COVID-19 responders, leveraging insights from prior infectious disease outbreaks like H 1 N 1 and SARS (5).The panel compiles a comprehensive array of critical events pertaining to emergency management decisions.Utilizing the Delphi method, a consistent causality estimation matrix is established among these events.Following the creation of a cross-impact matrix, the most impactful events, representing the top 5 and 15%, are visually depicted.Initially, the model facilitates multiple scenario analyses to identify crucial contingencies.Subsequently, it discerns correlations between actual events to delineate outcome trends stemming from varied The trend of the prediction probabilities of four outcome events.Drawing from real-world epidemic occurrences and scenario simulations, this paper enables the assessment of the efficacy of critical emergency management measures, the identification of pivotal events for future epidemic combat, and the formulation of targeted recommendations to ameliorate epidemic-induced losses and refine future emergency management protocols.

IC 1 :
Infectious disease isolation and treatment capacity: The city can isolate and treat patients with infectious diseases.IC 2 : Infectious disease source detection capability: The city can quickly conduct rapid detection of the cause of the disease.

IC 3 :
Infectious disease infectivity assessment: The city can quickly assess the infectious characteristics or transmission routes of infectious diseases.IC 4 : Medical treatment.IC 5 : Government emergency response plan: The city has an excellent emergency response plan for infectious diseases.IC 6 : Government emergency response capability: The city has an infectious disease control agency, conducts frequent emergency drills, and has good response capability.IC 7 : Public self-protection ability: The public knows the general knowledge of infectious diseases and has good selfprotection ability.IC 8 : Government communication capability: Have internal communication procedures and public communication plans and channels.IC 9 : Public trust: The public trusts the government and complies with government emergency instructions.IC 10 : Vaccine: There is no vaccine for infectious disease.
found, prompting the public to avoid public places and crowded places, and to wear masks when going out.Jan 1, 2020 An outbreak response leadership team is established.CDC and Chinese Academy of Medical Sciences receive cases and immediately carry out pathogen identification.Jan 3 Further pathogen identification China regularly and proactively informs the World Health Organization of outbreak information.Jan 4 Develop a workbook for medical treatment of viral pneumonia of known cause and reach a consensus with the CDC for close liaison.
stations are temporarily closed for departures from Wuhan.Provinces across the country activate provinciallevel emergency response for major public health emergencies one after another.Jan 24 National medical teams and public health personnel are mobilized from various regions and the military to assist Hubei Province and Wuhan City.Jan 25 Sent steering teams to Wuhan and other areas with serious outbreaks to promote strengthening of front-line prevention and control efforts.Jan 26 Extend the 2020 Spring Festival holiday and postpone the opening of colleges, universities, primary and secondary schools, and kindergartens around the country.Jan 27The central steering team is stationed in Wuhan to comprehensively strengthen guidance and supervision of the frontline prevention and control of the epidemic.

FIGURE 7
FIGURE 7 Number of new confirmed COVID-19 diagnoses on January 30.

FIGURE 8
FIGURE 8Number of people cured after having COVID-19 on January 30.

FIGURE 12
FIGURE 12Number of people cured after having COVID-19 on February 14.

TABLE 1
Rating scale.

TABLE 2
Outcome events analysis.

TABLE 7
Total impact on positive events.

TABLE 6
OE 4 ordered influences table.The figure illustrates that vaccines (IC 10 ), capacity for infectious disease isolation and treatment (IC 1 ), medical resource reserves (IC 4 ), government contingency plans (IC 5 ), public trust (IC 9), government emergency response capacity (IC 6 ), government communication capacity (IC 8 ), public self-protection (IC 7 ), infectious disease source detection (IC 2 ), and assessment of infectious disease transmission capacity (IC 3 ) trigger a series of dynamic events (DE 4 , DE 9 , DE 14 , DE 8 , DE 15 , DE 13 , DE 7 , DE 6 , DE 16 , DE 5 , DE 11), which decrease the likelihood of death (OE 2 ) and increase the chances of infectious disease control (OE 3 ) and public trust (OE 4 ).Prompt treatment of infected patients (DE 1 ) directly limits movement restrictions (DE 17 ), while vaccine shortages (IC 10 ) negatively impact decontamination efforts (DE 4 ), emphasizing the need for active vaccine development within decontamination measures (DE 4 ).Enhancing the capacity for isolating and treating infectious diseases (IC 1 ), developing government contingency plans (IC 5 ), and creating effective vaccines against novel viruses (IC 10 ) will greatly benefit decontamination operations (DE 4 ).Insufficient medical resource reserves (IC 4 ) and the absence of effective vaccines against novel viruses (IC 1 8) will lead to the spread of rumors (DE 1 0).Reduced public panic (DE 9 ) and low infectious disease transmission capacity (IC 3 ) would significantly improve the assessment of infectious disease transmission capacity (DE 3 ).Strong public trust (IC 9 ), high levels of infectious disease source detection (IC 2 ), effective causative agent identification (DE 2 ), and improved public self-protection (IC 7 ) will notably decrease the likelihood of partial public non-cooperation (DE 16 ).Effective government emergency response (IC 6 ) and communication (IC 8 ) will effectively mitigate non-cooperation among healthcare workers (DE 15 ).

TABLE 8
Total impact on negative events.

TABLE 9
Prediction probabilities of the other events in initial conditions analysis.To curb the spread of COVID-19, China enforced traffic control measures in Wuhan city on January 23, 2020, resulting in DE 7 = DE 9 = DE 10 = DE 17 = DE 6 = 1, DE 18 = 0.

TABLE 11
Prediction probabilities of the other events in dynamic events analysis.

TABLE 13
Timeline of major rescue events after COVID-19 in Wuhan.
Yuan et al. 10.3389/fpubh.2024.1368154Frontiers in Public Health 18 frontiersin.orginsights for this study, particularly in response measures for Southeast and South Asia (59).However, most studies only address single points in emergency management, such as evacuation or healthcare responses (60, 61).Unlike Brooks et al. 's study, this paper examines the dynamic interaction between event sets and constructs a scenario model for analyzing COVID-19 emergency management in Wuhan (7).It presents a hypothetical urban outbreak response scenario based on COVID-19 occurrences, highlighting the impact of critical events on outcomes and using directed graphs to illustrate event relationships.The leaders' reluctance to share information and healthcare workers' non-cooperation trigger other dynamic events, emphasizing the importance of emergency preparedness in epidemic response.The model proposed in this research enriches the future pandemic response framework proposed by Amir Khorram-Manesh et al. (62).
(19)gency management initiatives that synergistically influence one another form micro-sets, enabling the dissection of their impact on human casualties and economic losses.Scenario simulations derived from diverse emergency management strategies prove more scientifically robust than single-factor approaches(19).Concurrently, this study corroborates the adverse effects of rumors and information leakage on infectious disease containment (34).Restricting people's movement significantly curtails casualties, while the swift depletion of medical supplies and nationwide economic shutdowns exacerbate economic losses.Although rapid economic recovery from infectious disease-induced losses remains challenging, a well-crafted emergency plan serves as a cornerstone for restoring public confidence and bolstering trust.Enhanced public awareness of effective epidemic control measures and self-protection strategies expedites disease coping mechanisms.However, casualties, information leaks, and rumors can escalate public panic, underscoring the need for proactive guidance through essential medical interventions and authoritative dissemination of diseaserelated information by governmental bodies.The findings underscore the imperative of emergency preparedness in mitigating severe economic losses, casualties, and societal ramifications precipitated by infectious diseases.During the primary stage of emergency response, concerted rescue efforts must collaborate to achieve optimal outcomes.Simulation outcomes demonstrate that the effective implementation of multiple emergency management measures significantly diminishes the probability of infectious disease-related damage.The analysis underscores the pivotal role of establishing an emergency command center and the proactive governmental involvement in assuaging public apprehension and fostering trust.Prioritizing the isolation and monitoring of individuals exposed to infectious diseases emerges as a paramount objective in emergency management, effectively curbing disease transmission and mitigating casualties and economic losses.