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STUDY PROTOCOL article
Front. Public Health
Sec. Public Health Education and Promotion
Volume 12 - 2024 |
doi: 10.3389/fpubh.2024.1407726
This article is part of the Research Topic Empowering Individuals: Promoting Health Literacy through Curriculum and Science Communication View all 3 articles
Research Protocol for Bridging Research Accurate Information and Dialogue (BRAID)-Clinical Trials: a mixed-methods study of a community-based intervention to improve trust and diversify participation in clinical trials
Provisionally accepted- 1 Family & Social Medicine and Psychiatry & Behavioral Sciences, Albert Einstein College of Medicine, Bronx, United States
- 2 Albert Einstein College of Medicine, New York City, New York, United States
- 3 Department of Epidemiology and Population Health, Albert Einstein College of Medicine, The Bronx, New York, United States
- 4 Office of Community and Population Health, Montefiore Medical Center, Bronx, New York, United States
- 5 Trinity College of Arts and Sciences, Duke University, Durham, North Carolina, United States
- 6 Department of Child and Adolescent Psychiatry, NYU Langone Medical Center, New York, United States
- 7 NYC Health+Hospitals/Bellevue, New York, United States
Cultural beliefs, personal experiences, and historic abuses within the healthcare system-rooted in structural racism-all contribute to community distrust in science and medicine. This lack of trust, particularly within underserved communities, contributes to decreased participation in clinical trials and a lack of representation in the data. Open dialogue about community concerns and experiences related to research participation and medical care processes can help build trust and change attitudes and behaviors that affect community health. This protocol outlines an approach to increase trust in science and clinical trials among communities in the Bronx, New York that are typically underrepresented in research data. Bridging Research, Accurate Information and Dialogue (BRAID) is a two-phased, evidence-based community engagement model that creates safe spaces for bilateral dialogues between trusted community messengers, and clinicians and scientists. The team will conduct a series of BRAID Conversation Circles on the topic of clinical trials with local trusted community messengers. Participants will be members of the community who are perceived as "trusted messengers" and can represent the community's voice because they have insight into "what matters" locally. Conversation Circles will be audiotaped, transcribed, and analyzed to identify emergent challenges and opportunities surrounding clinical trial participation. These key themes will subsequently inform the codesign and co-creation of tailored messages and outreach efforts that community participants can disseminate downstream to their social networks. Surveys will be administered to all participants before and after each Conversation Circle to understand participants experience and evaluate changes in knowledge and attitudes about clinical trials, including protections for research participants the advantages of having diverse representation. Changes in motivation and readiness to share accurate clinical trial information downstream will also be assessed. Lastly, we will measure participants dissemination of codesigned science messages through their social networks by tracking participant specific resource URLs of materials and videos posted on a BRAID website. This protocol will assess the effectiveness and adoptability of an innovative CBPR model that can be applied to a wide range of public health issues and has the potential to navigate the ever-changing needs of the communities that surround health systems.
Keywords: community experts, Conversation circles, Community Engagement, BRAIDer, trusted messengers, Braid, diversity in clinical trials, Trust in Science
Received: 27 Mar 2024; Accepted: 13 Aug 2024.
Copyright: © 2024 Gutnick, Lozano, Rodriguez Martinez, Wang, Williams, Rapkin and Gonzalez-Lepage. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Damara Gutnick, Family & Social Medicine and Psychiatry & Behavioral Sciences, Albert Einstein College of Medicine, Bronx, United States
Patricia Lozano, Albert Einstein College of Medicine, New York City, 10461, New York, United States
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Katherine Wang
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