AUTHOR=Zhong Huanxia , Pan Wenwei , Chen Binbin , Gu Jiamin , Liang Yu , Sun Guoli , Huang Xinghua , Yuan Huitao , Guo Haina , Zhong Ling , Li Zhuanfen , Zhou Ping , Zeng Siliang , Tang Li 

TITLE=A real-world, cross-sectional, and longitudinal study on high-risk human papillomavirus genotype distribution in 31,942 women in Dongguan, China

JOURNAL=Frontiers in Public Health

VOLUME=Volume 12 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1409030

DOI=10.3389/fpubh.2024.1409030

ISSN=2296-2565

ABSTRACT=Background: Persistent Human Papillomavirus (HPV) infection remains a key risk factor for cervical cancer. HPV-based primary screening is widely recommended in clinical guidelines, and further longitudinal studies are needed to optimize strategies for detecting high-grade cervical lesions compared to cytology.Methods: From November 2015 to December 2023, a total of 31,942 participants were included in the real-world observational study. Among those, 4,219 participants underwent at least two rounds of HPV tests, and 397 completed three. All were tested for high-risk types of HPV 16