AUTHOR=Maison David P. , Tasissa Hawi , Deitchman Amelia , Peluso Michael J. , Deng Youping , Miller F. DeWolfe , Henrich Timothy J. , Gerschenson Mariana 

TITLE=COVID-19 clinical presentation, management, and epidemiology: a concise compendium

JOURNAL=Frontiers in Public Health

VOLUME=Volume 13 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1498445

DOI=10.3389/fpubh.2025.1498445

ISSN=2296-2565

ABSTRACT=Coronavirus Disease 2019, caused by severe acute respiratory coronavirus 2, has been an ever-evolving disease and pandemic, profoundly impacting clinical care, drug treatments, and understanding. In response to this global health crisis, there has been an unprecedented increase in research exploring new and repurposed drugs and advancing available clinical interventions and treatments. Given the widespread interest in this topic, this review aims to provide a current summary—for interested professionals not specializing in COVID-19—of the clinical characteristics, recommended treatments, vaccines, prevention strategies, and epidemiology of COVID-19. The review also offers a historical perspective on the pandemic to enhance understanding.