AUTHOR=Liang Ying , Li Shuangqi , Meng Lianxin , Wang Xisheng , He Zhichuan , Lu Qingmei , Huang Li , Li Yijuan , Xie Weiping , Ji Hongyun TITLE=The mediating role of wellbeing in the relationship between health behaviors and quality of life in people with hepatogenous diabetes JOURNAL=Frontiers in Public Health VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1529158 DOI=10.3389/fpubh.2025.1529158 ISSN=2296-2565 ABSTRACT=AimThis study aimed to investigate the relationship between health behaviors, wellbeing, and health-related quality of life (HRQoL) in patients with hepatogenous diabetes (HD), with a focus on exploring the mediating effect of the wellbeing index.DesignA cross-sectional analysis was conducted on 161 people with HD from January to December 2021 at a Grade III, Class A hospital's Department of Gastroenterology in Guangxi Province.MethodsHealth behaviors were assessed using the Health-Promoting Lifestyle Profile (HPLP-C), HRQoL was measured with the Chronic Liver Disease Questionnaire (CLDQ), and emotional wellbeing was evaluated using the WHO-5 Wellbeing Index. Correlation analysis and a mediation model were used to explore the relationships between health behaviors, wellbeing, and HRQoL.ResultsThe results revealed a significant positive correlation between health behaviors and HRQoL (r = 0.385, p < 0.01) as well as between the wellbeing index and HRQoL (r = 0.513, p < 0.01). The wellbeing index partially mediated the relationship between health behaviors and HRQoL, accounting for 44.47% of the total effect. Despite generally favorable health behaviors, people with HD exhibited poor HRQoL (59.03 ± 17.47), with 28.6% experiencing depressive symptoms.ConclusionImproving psychological wellbeing plays a crucial role in enhancing HRQoL among people with HD. Interventions should target both health behaviors and mental health to foster a more positive psychological state and improve overall patient outcomes.