AUTHOR=Wang Yueyang , Deng Ruigang , Geng Xinyu TITLE=Exploring the integration of medical and preventive chronic disease health management in the context of big data JOURNAL=Frontiers in Public Health VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1547392 DOI=10.3389/fpubh.2025.1547392 ISSN=2296-2565 ABSTRACT=Chronic non-communicable diseases (NCDs) pose a significant global health burden, exacerbated by aging populations and fragmented healthcare systems. This study employs a comprehensive literature review method to systematically evaluate the integration of medical and preventive services for chronic disease management in the context of big data, focusing on pre—hospital risk prediction, in—hospital clinical prevention, and post—hospital follow—up optimization. Through synthesizing existing research, we propose a novel framework that includes the development of machine learning models and interoperable health information platforms for real—time data sharing. The analysis reveals significant regional disparities in implementation efficacy, with developed eastern regions demonstrating advanced closed—loop management via unified platforms, while western rural areas struggle with manual workflows and data fragmentation. The integration of explainable AI (XAI) and blockchain—secured care pathways enhances clinical decision—making while ensuring GDPR—compliant data governance. The study advocates for phased implementation strategies prioritizing data standardization, federated learning architectures, and community—based health literacy programs to bridge existing disparities. Results show a 30–35% reduction in redundant diagnostics and a 15–20% risk mitigation for cardiometabolic disorders through precision interventions, providing a scalable roadmap for resilient public health systems aligned with the “Healthy China” initiative.