AUTHOR=Hernandez-Martinez Jordan , Cid-Calfucura Izham , Vázquez-Carrasco Edgar , Fritz-Silva Nicole , Herrera-Valenzuela Tomás , Branco Braulio Henrique Magnani , Zapata-Bastias José , Valdés-Badilla Pablo TITLE=Effects of boxing interventions on physical fitness and health-related quality of life in older people with Parkinson’s disease: a systematic review with meta-analysis JOURNAL=Frontiers in Public Health VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1589512 DOI=10.3389/fpubh.2025.1589512 ISSN=2296-2565 ABSTRACT=ObjectiveThis systematic review with meta-analysis aimed to evaluate the available body of published peer-reviewed studies on the effects of boxing (BOX) interventions on balance, cardiorespiratory fitness, motor function, and health-related quality of life (HRQoL) in older people with Parkinson’s disease (PD).MethodsA comprehensive search of the literature, including peer-reviewed randomized and non-randomized controlled trials, was conducted to December 2024 in the databases of PubMed, Medline, Psychology and Behavioral Sciences Collection (EBSCO), CINAHL Complete, Scopus, and Web of Science (core collection). A random-effects model was employed, and Hedge’s g effect sizes (ES) were computed. The GRADE, RoB 2, ROBIN-1, TESTEX, and PRISMA tools evaluated the methodological quality and certainty of evidence. The protocol (code: CRD42024614097) was registered in PROSPERO.ResultsEight studies were included, with 100 older people with PD, of which only three could be meta-analyzed. No significant effects were evident (p = 0.05), which were small to moderate effects of BOX on ABC-Scale (ES = −0.56; p = 0.13), Timed Up-And-Go (TUG; ES = 0.24; p = 0.34), TUG dual task (ES = 0.20; p = 0.41), 6-min walking test (ES = 2.16; p = 0.23), and PD Quality of Life Questionnaire (ES = −0.009; p = 0.98).ConclusionBOX interventions do not significantly improve balance, cardiorespiratory fitness, and health-related quality of life in older people with PD.