AUTHOR=Zhuang Yiyi , Kwang Cheol Kim , Botabara-Yap Mary Jane , Zhao Kuan , Ramos Rowena Imelda A. , Cao Wenming TITLE=Factors associated with reproductive health and health education participation among female college students in China JOURNAL=Frontiers in Public Health VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1627669 DOI=10.3389/fpubh.2025.1627669 ISSN=2296-2565 ABSTRACT=PurposeTo investigate sociodemographic determinants of reproductive health disparities and health education participation among Chinese female college students (CFCs).MethodsA nationally representative sample of 1,013 students from 12 provinces (October to November 2024) completed validated questionnaires. Multilevel logistic regression analyzed clustered data (school-level ICC = 0.19).ResultsSignificant associations were observed between sociodemographic factors education level, household registration, only child status, academic major and reproductive health outcomes (p < 0.05). Key findings include pronounced urban–rural inequities, with urban students demonstrating 4.3-fold higher HPV vaccination rates than rural peers (78.5% vs. 45.7%, aOR = 4.3, 95% CI: 3.2–5.8), alongside elevated dysmenorrhea prevalence among rural students (56.9% vs. 43.5%, aOR = 1.8, 95% CI: 1.4–2.3). Academic stressors significantly impacted health outcomes, as postgraduate students exhibited a 60% higher dysmenorrhea risk versus undergraduates (60.9% vs. 50.8%, aOR = 1.6, 95% CI, 1.2–2.1), while paradoxically, medical students showed lower HPV vaccination uptake than non-medical peers (58.0% vs. 74.3%, aOR = 2.1), attributed to clinical skepticism about vaccine safety. Furthermore, health education engagement was limited (46.1% participation), with 52.4% relying on online platforms for health information—highlighting critical gaps in institutional health promotion and digital misinformation risks. Therefore, addressing these multifaceted socioeconomic, educational, and structural barriers is essential for improving reproductive health equity in this population.ConclusionMultifaceted strategies addressing socioeconomic barriers, health education gaps, and digital misinformation are critical to improving reproductive health in female college students.