AUTHOR=Caner Vedat TITLE=Profiling safety behavior in clinical laboratory environments JOURNAL=Frontiers in Public Health VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1681513 DOI=10.3389/fpubh.2025.1681513 ISSN=2296-2565 ABSTRACT=IntroductionLaboratory safety behavior is crucial for minimizing risks in high-hazard clinical settings, yet behavioral non-compliance persists as a leading cause of laboratory accidents despite established protocols.MethodsThis study evaluated safety behavior among 92 personnel employed in genetic diagnostic laboratories in Istanbul using a validated 34-item safety behavior scale. Principal component analysis (PCA), multiple linear regression, and k-nearest neighbors (k-NN) classification were employed to analyze the data.ResultsThe analysis revealed three underlying behavioral dimensions: personal compliance, proactive behavior, and institutional engagement. Regression analysis indicated that perceived institutional support and the frequency of safety training were significant predictors of overall safety behavior (R2 = 0.47, p < 0.001). Furthermore, the k-NN classifier utilizing PCA-derived components achieved an 88% accuracy rate in distinguishing high and low compliance profiles.DiscussionThese findings underscore the utility of multivariate behavioral analytics in profiling laboratory safety behavior and highlight the potential of data-informed, classification-based strategies to enhance safety interventions. Adopting behaviorally tailored approaches to training and institutional support may markedly improve compliance and mitigate risk in laboratory environments.