AUTHOR=Basimah Albalooshy , Faro Scott Scott , Yuan Hsiangkuo , Talekar Kiran , Mondel Prabath , Qiu Enchao , Chaganti Joga TITLE=Imaging hallmarks of idiopathic intracranial hypertension and insights into pathogenesis JOURNAL=Frontiers in Radiology VOLUME=Volume 5 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/radiology/articles/10.3389/fradi.2025.1605777 DOI=10.3389/fradi.2025.1605777 ISSN=2673-8740 ABSTRACT=Idiopathic Intracranial hypertension (IIH), also referred to as pseudotumor cerebri, is a term used to describe increased intracranial pressure in the absence of a known identifiable secondary cause. Despite advancements of neuroimaging techniques, imaging of the pathological underpinnings in the diagnosis of IIH has been limited. Although the causation of IIH has been ascribed to increased Cerebrospinal Fluid production and disordered drainage through the dural sinuses, new evidence shows that the glymphatic system which is an alternate pathway of drainage is likely to play a pivotal role. In this review, we address the pathophysiological underpinnings in the causation of IIH and discusses characteristic anatomical imaging findings on conventional MRI and explore the role of advanced imaging techniques.