AUTHOR=Eyles Jillian P. , Sharma Saurab , Telles Rosa Weiss , Namane Mosedi , Hunter David J. , Bowden Jocelyn L. TITLE=Implementation of Best-Evidence Osteoarthritis Care: Perspectives on Challenges for, and Opportunities From, Low and Middle-Income Countries JOURNAL=Frontiers in Rehabilitation Sciences VOLUME=Volume 2 - 2021 YEAR=2022 URL=https://www.frontiersin.org/journals/rehabilitation-sciences/articles/10.3389/fresc.2021.826765 DOI=10.3389/fresc.2021.826765 ISSN=2673-6861 ABSTRACT=The ‘Joint Effort Initiative’ (JEI) is an international consortium of health professionals, researchers, and consumers under the auspices of the Osteoarthritis Research Society International (OARSI). The JEI was formed with a vision to improve the implementation of coordinated programs of best evidence osteoarthritis care globally. To better understand some of the issues around osteoarthritis care in low- and middle-income countries (LMICs), the JEI Steering Committee invited clinician researcher representatives from South Africa, Brazil and Nepal to discuss their perspectives on challenges and opportunities to implementing best-evidence osteoarthritis care at the OARSI World Pre-Congress Workshop. We summarise and discuss the main themes of the presentations in this paper. The challenges to implementing evidence-based osteoarthritis care identified in LMICs include health inequities, unaffordability of osteoarthritis management and the failure to recognise osteoarthritis as an important disease. Fragmented healthcare services and a lack of health professional knowledge and skills are also important factors affecting osteoarthritis care in LMICs. We discuss considerations for developing strategies to improve osteoarthritis care in LMICs. Existing opportunities may be leveraged to facilitate the implementation of best-evidence osteoarthritis care. We also discuss strategies to support the implementation, such as the provision of high-quality health professional and consumer education, and systemic healthcare reforms.