AUTHOR=Tesarik Jan , Mendoza-Tesarik Raquel 

TITLE=Patient-tailored reproductive health care

JOURNAL=Frontiers in Reproductive Health

VOLUME=Volume 4 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/reproductive-health/articles/10.3389/frph.2022.917159

DOI=10.3389/frph.2022.917159

ISSN=2673-3153

ABSTRACT=Patient-tailored reproductive health care represents an important challenge for the current practice of infertility prevention, diagnosis and treatment. This approach is based on the concept of precision medicine, taking into account genetic, epigenetic, metabolic and lifestyle characteristis of each individual patient. Even though this goal is still far from being wholly achieved, some aspects can already be put into practice nowadays. Personalization can be based on a comprehensive analysis and synthesis of the patients’ personal and familial history, taking into account outcomes of previous assisted reproduction technique (ART) attempts, if available, and confronting these data with the past and the latest clinical and laboratory examination outcomes. This complex information will be used to determine the personalized management strategy, including preventive measures, completion of the diagnosis, and the choice of the clinical treatments and laboratory methods to be used. The follow-up of women who have become pregnant as a result of the ART attempt has also to be personalized. This should be done taking into account both the basic data extracted from the patient’s file and those derived from the experience gathered during the latest attempt. This mainly applies to the type and frequency of the examinations of serum hormone levels during pregnancy and the consequent adaptations of hormonal treatments used to prevent pregnancy loss. Last but not least, the individual condition of each couple has to be taken into account when counseling the patients as to the urgency of the actions to be taken to resolve their fertility problem.