Frontiers in Reproductive Health

Original Research

Published on 23 Apr 2026

Maturation-associated changes in Sertoli cells following in vitro culture of frozen-thawed prepubertal mouse testicular tissue

in Andrology

Laura Moutard
Marion Dufour
Nathalie Rives
Magali Basille-Dugay
Eva Chemin
Valentin Rousseau
Aurélie Feraille
Christine Rondanino
Ludovic Dumont

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1835316

961 views

Review

Published on 23 Apr 2026

Research progress on active ingredients of traditional Chinese medicine in the treatment of asthenozoospermia

in Andrology

Hongyu Wang
Haichao Ge
Chunyan Ge
Lianwen Zheng
Lianhai Jin
Donghai Zhao

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1837460

940 views

Original Research

Published on 21 Apr 2026

Intracavernosal UC-MSC secretome therapy for severe erectile dysfunction: a clinical anatomy pilot study with elastography and Doppler assessment

in Andrology

Ria Margiana
Supardi Supardi
Maria Paulina Budyandini Dyah Pramesti
Heri Suroto
Reny I'tishom
Fatkhurrohmah Leo Amalia
M. Ikhsan Nugroho
Andi Ahmad Thoriq Pratama
Muhammad Hidayat Surya Atmaja
Kristophorus Jonathan Wibowo

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1775672

1,453 views

Original Research

Published on 20 Apr 2026

Clomiphene citrate and human chorionic gonadotropin treatment before microdissection testicular sperm extraction in non-obstructive azoospermia: a retrospective non-randomized series

in Andrology

Mohammad Al-Zubi
Mohammad Ghassab Deameh
Ahmed Khaled Awawdeh
Rahaf Jamil Mohammad
Ayah Ahmad Shannaq
Salma Mo'taz Qdisat
Ruba Mahmoud Mansi
Anas Yousef Tanashat
Mohammad Ahmad Mubarak
Balqis Abu-Khadra

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1696244

1,366 views

Review

Published on 20 Apr 2026

Advances in immunological research on male infertility

in Andrology

Zejun Liu
Xinran Yang
Yuan Ji
Shen Wang
Jingqi Wang

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1752758

1,154 views

Hypothesis and Theory

Published on 10 Apr 2026

Alternatives to serum testing for transdermal testosterone monitoring: a review of clinical data and correlation with clinical response

in Andrology

Mark S. Newman
Jaclyn Smeaton
George Gillson
Azra Jaferi

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1804311

2,030 views

Systematic Review

Published on 24 Feb 2026

Are we still too late to preserve the testes? A global survey of delayed consultation and risk factors for testicular torsion: a systematic review and meta-analysis

in Andrology

Miao Sun
Chengjun Yu
Zhongyao Zeng
Yuanzhi Song
Fengming Ji
Yang Liu
Shiyu Peng
Bojingjia Liu
Runchang Wang
Shengde Wu

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1735652

1,271 views

Original Research

Accepted on 17 Feb 2026

A Self-Controlled Longitudinal Study on the Impact of COVID-19 on Semen Parameters: The Critical Role of Fever and Time Intervals

in Andrology

Wei Cui
Jing-xian Gao
Xiang-yang Miao

Frontiers in Reproductive Health

2,118 views

Clinical Trial

Published on 12 Feb 2026

Efficacy and safety of ashwagandha root extract on sexual health in healthy Men: a prospective, randomized, double-blind, placebo-controlled study

in Andrology

Aman Khanna
Mallika Khanna
Parth Panchal

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1774098

9,723 views
1 citation

Original Research

Published on 23 Jan 2026

Impact of advanced paternal age on reproductive outcomes in preimplantation genetic testing cycles of young female: a retrospective cohort study

in Andrology

Nana Kong
Min Li
Aiming Wang
Bin Liu
Yuliang Shen
Qingao Xu
Xina Wang
Zhuqing Ji
Xueying Yu
Wei Shang

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1750842

2,143 views

Original Research

Published on 22 Jan 2026

Developing a persona-driven, mHealth-enabled care model for young men with hypogonadism: a methods-based approach to early risk stratification and prevention

in Andrology

Francesco Garifalos
Davide Menafra
Cristina de Angelis
Angelica Larocca
Michele Virgolesi
Sara Aprano
Vincenzo De Luca
Teresa Rea
Erminia Attaianese
Mariangela Perillo

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1691309

910 views

Original Research

Published on 12 Jan 2026

Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes

in Andrology

Han Liang
Jianlong Sun
Zaoxu Xu
Defeng Fu
Hangyu Zhang
Xiaoran Zhou
Chen Li
Huihua Xia
Gailing Li
Renjie Liao

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1747902

2,220 views

Review

Published on 12 Jan 2026

IQ motif family genes in male infertility: pathogenesis, mechanisms, and clinical perspectives

in Andrology

Peng Zhang
Sai Lu
Hui Qian
Jiu Yin
Haiying Peng
Hemei Li

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1719934

1,677 views

Original Research

Published on 04 Dec 2025

Evaluation of a low-intensity pulsed ultrasound for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a randomized controlled trial

in Andrology

Jiahao Huang
Zedong Liao
Shankun Zhao
Bodong Lv
Ke Liang

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1714803

2,474 views

Review

Published on 18 Nov 2025

Potential therapeutic targets in the prevention of testicular ischemia-reperfusion injury

in Andrology

Richard Adedamola Ajike
Ayodeji Folorunsho Ajayi
Olubunmi Simeon Oyekunle
Waidi Adeoye Saka
Sodiq Opeyemi Hammed
Oreoluwa Janet Adedeji
Olajumoke Deborah Ogunleye
Oluwaseun Samuel Hezekiah
Oluwakemi Victoria Olayinka-Akinpelu
Babatunde Adebola Alabi

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1706914

3,225 views

Case Report

Published on 18 Nov 2025

Expanding the phenotypic spectrum associated with CFAP43 mutations: a case report of familial male infertility with respiratory manifestations

in Andrology

Fawaz Awad
Razan Abukhaizaran
Shahira Al Jabi
Mustafa Nabilsi
Laith A. Ayasa
Majd A. AbuAlrob
Haneen Owienah
Hanin Kassem
Moien Kanaan

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1609938

1,848 views

Original Research

Published on 06 Nov 2025

Trends in male infertility burden in South Asia: a 30-year analysis of DALYs, prevalence, and future projections based on GBD 2021

in Andrology

Kaleem Maqsood
Tahir Mehmood
Humayoun Huma Maqbool
Ali Afzal
Muhammad Faisal Maqbool
Mahnoor Fatima
Tayyba Jan
Samina Ashraf
Muhammad Babar Khawar
Chatchai Muanprasat

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1697925

3,506 views
2 citations

Original Research

Published on 29 Oct 2025

Distinct phenotypic signatures between anejaculation and premature ejaculation: evidence from a large clinical cohort

in Andrology

Tianbiao Zhang
Ziang Shi
Rui Wang
Tao Zheng
Yonghao Nan
Kunlong Lv

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1711365

2,321 views

Original Research

Published on 29 Sep 2025

Enhancing penile function: the impact of a regenerative multimodal protocol on erectile dysfunction

in Andrology

Andrés Soto-Rodríguez
Carla Pastora-Sesín
Juan Antonio Valverde-Espinoza
Sergio Campos-Sanchez
Massimiliano Mauro-Stamati
Vincent Giampapa
Víctor Urzola
José Rafael Rojas-Solano

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1601354

8,394 views

Original Research

Published on 29 Sep 2025

Temporal shifts in semen parameters across a major COVID-19 outbreak wave: a retrospective cohort study using epidemiological time-windows

in Andrology

Hai Wang
Xianjue Zheng
Haojie Pan
Jiayong Zheng
Zitong Xu

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1691216

1,888 views

Review

Published on 22 Aug 2025

Vitamin D in male sexual functions: unwrapping the sunshine hormone activities in erectile function and beyond

in Andrology

Adeyemi Fatai Odetayo
Grace Edet Bassey
Grace Ayobami Fajemidagba
Kazeem Bidemi Okesina
Moses Agbomhere Hamed

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1594664

35,003 views

Original Research

Published on 05 Aug 2025

Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty

in Andrology

Zhenyu Li
Zhiguang Zhao
Geng Zhang
He Wang
Bo Zhang
Wei Zhang

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1555597

2,572 views
6 citations

Editorial

Published on 28 Jul 2025

Editorial: Oxidative stress and male fertility

in Andrology

Roland E. Akhigbe

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1657872

2,027 views
5 citations

Review

Published on 05 Jun 2025

State-of-the-art approaches in the investigation of human seminal bacteriome using metagenomic methods

in Andrology

Jan Hofman
Petra Brenerova
Petra Borilova Linhartova

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1557912

3,806 views
1 citation

68 articles

articles

Maturation-associated changes in Sertoli cells following in vitro culture of frozen-thawed prepubertal mouse testicular tissue

Research progress on active ingredients of traditional Chinese medicine in the treatment of asthenozoospermia

Intracavernosal UC-MSC secretome therapy for severe erectile dysfunction: a clinical anatomy pilot study with elastography and Doppler assessment

Clomiphene citrate and human chorionic gonadotropin treatment before microdissection testicular sperm extraction in non-obstructive azoospermia: a retrospective non-randomized series

Advances in immunological research on male infertility

Alternatives to serum testing for transdermal testosterone monitoring: a review of clinical data and correlation with clinical response

Are we still too late to preserve the testes? A global survey of delayed consultation and risk factors for testicular torsion: a systematic review and meta-analysis

A Self-Controlled Longitudinal Study on the Impact of COVID-19 on Semen Parameters: The Critical Role of Fever and Time Intervals

Efficacy and safety of ashwagandha root extract on sexual health in healthy Men: a prospective, randomized, double-blind, placebo-controlled study

Impact of advanced paternal age on reproductive outcomes in preimplantation genetic testing cycles of young female: a retrospective cohort study

Developing a persona-driven, mHealth-enabled care model for young men with hypogonadism: a methods-based approach to early risk stratification and prevention

Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes

IQ motif family genes in male infertility: pathogenesis, mechanisms, and clinical perspectives

Evaluation of a low-intensity pulsed ultrasound for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a randomized controlled trial

Potential therapeutic targets in the prevention of testicular ischemia-reperfusion injury

Expanding the phenotypic spectrum associated with CFAP43 mutations: a case report of familial male infertility with respiratory manifestations

Trends in male infertility burden in South Asia: a 30-year analysis of DALYs, prevalence, and future projections based on GBD 2021

Distinct phenotypic signatures between anejaculation and premature ejaculation: evidence from a large clinical cohort

Enhancing penile function: the impact of a regenerative multimodal protocol on erectile dysfunction

Temporal shifts in semen parameters across a major COVID-19 outbreak wave: a retrospective cohort study using epidemiological time-windows

Vitamin D in male sexual functions: unwrapping the sunshine hormone activities in erectile function and beyond

Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty

Editorial: Oxidative stress and male fertility

State-of-the-art approaches in the investigation of human seminal bacteriome using metagenomic methods