AUTHOR=Padilla-Gálvez Mónica , Arteaga-Vazquez Leo J. , Villaseñor-Altamirano Ana B. , Balderas-Martínez Yalbi Itzel , Collado-Torres Leonardo , De Las Rivas Javier , Blanco-Melo Daniel , Medina-Rivera Alejandra TITLE=Identification of regulons modulating the transcriptional response to SARS-CoV-2 infection in humans JOURNAL=Frontiers in RNA Research VOLUME=Volume 2 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/rna-research/articles/10.3389/frnar.2024.1334873 DOI=10.3389/frnar.2024.1334873 ISSN=2813-7116 ABSTRACT=We appreciate your consideration of our manuscript entitled "Identification of regulons modulating the transcriptional response to SARS-CoV-2 infection in human" for publication in the Frontiers in RNA Research. We thank you and the reviewers for your invaluable feedback during the review process. We have addressed the reviewers' comments and incorporated necessary revisions to enhance the clarity of our work.Below, we address each of the reviewer's comments point-by-point and highlight where changes were made in the manuscript's main text. We greatly appreciate the thoughtful reviews; the reviewers' suggestions have greatly improved our work. We expect this manuscript to be of interest to the scientific community. We hope you now find it acceptable for publication.Sincerely,