AUTHOR=Roldán Ainoa , Monteagudo Pablo , Cordellat Ana , Sanchis-Soler Gema , Blasco-Lafarga Cristina TITLE=Inspiratory Muscle Strength and Cardiorespiratory Fitness Association With Health-Related Quality of Life in Healthy Older Adults JOURNAL=Frontiers in Sports and Active Living VOLUME=Volume 3 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/sports-and-active-living/articles/10.3389/fspor.2021.624947 DOI=10.3389/fspor.2021.624947 ISSN=2624-9367 ABSTRACT=The purpose of this study was to explore similarities and differences in the association between two capabilities implying the cardiorespiratory system (overall and multifactorial cardiorespiratory fitness; and inspiratory muscle strength) and health-related-quality-of-life (HRQoL), in a group of active seniors. 65 individuals (73.01±5.27 years; 53 women) who participated regularly in a multicomponent training program completed the EuroQol-5D-5L questionnaire, the 6-minutes-walking-test (6MWT) and the maximum inspiratory pressure test (MIP). Non-parametric correlations (Spearman's Rho) were conducted to analyze the association between HRQoL indices (EQindex and EQvas), MIP and 6MWT, considering both, the whole sample, and men and women separately. Furthermore, partial correlation was made by controlling age and sex. We found a moderate association between HRQoL and cardiorespiratory fitness (EQvas: r=0.324, p=0.009; EQindex: r=0.312, p=0.011). Considering sex, relationship EQvas-6MWT decrease to small (r=0.275) whereas EQindex-6MWT increased a bit but remained moderated (r=0.425). Considering women and men separately, the association between HRQoL and 6MWT appeared only in women, whilst the observed trend towards a large and positive association between EQindex and MIP, mediated by the covariate age, appeared only in men. Conversely to the cardiorespiratory fitness, MIP is not a limiting factor of HRQoL in healthy active elderly. Morevoer, MIP and HRQoL should be include in the assessment of exercise interventions because provide different information about cardiorespiratory deterioration. Furthermore, like aging process is different for men and women the association between MIP and cardiorespiratory fitness with HRQoL may behave differently, so keeping on research these associations could help to improve training programs for elderly.