AUTHOR=Ketelhut Sascha , Nigg Claudio R. TITLE=Heartbeats and high scores: esports triggers cardiovascular and autonomic stress response JOURNAL=Frontiers in Sports and Active Living VOLUME=Volume 6 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/sports-and-active-living/articles/10.3389/fspor.2024.1380903 DOI=10.3389/fspor.2024.1380903 ISSN=2624-9367 ABSTRACT=Introduction: Gaming is often labeled as sedentary behavior. However, competitive gaming, also known as esports, involves significant cognitive demands and may induce stress. This study aims to investigate whether the psychophysical demands during esports elicit a physiological stress response. Methods: Fourteen FIFA 21 and thirteen League of Legends players (23.3±2.8 years) were recruited for the study. Heart rate (HR), root mean square of successive differences between normal heartbeats (RMSSD), peripheral and central blood pressure (BP), pulse wave velocity (PWV), and energy expenditure (EE) were assessed during supine rest, seated rest, and competitive FIFA or League of Legends matches. Results: No significant group × condition interactions were observed for any of the outcomes. However, there were significant increases in mean HR (p < 0.001, η2p = .383), RMSSD (p = .019, η2p = .226), peripheral systolic BP (p < .001, η2p = .588), peripheral diastolic BP (p = .005, η2p = .272), central systolic BP (p = .005; η2p = .369), central diastolic BP (p = .016, η2p = .313), PWV (p = .004, η2p = .333), and EE (p < .001, η2p = .721) during both games compared to the seated rest condition. Conclusion: Despite the sedentary nature of esports, the psychophysical demands appear to elicit physiological responses. Interestingly, no significant differences were found between the different game genres.