AUTHOR=Vincent Heather K. , Popp Reed , Cicilioni Orlando , Vincent Kevin R. , Pezzullo Lydia , Martenson Matthew , Nixon Ryan M. TITLE=Reference biomechanical parameters and natural asymmetry among runners across the age spectrum without a history of running-related injuries JOURNAL=Frontiers in Sports and Active Living VOLUME=Volume 7 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/sports-and-active-living/articles/10.3389/fspor.2025.1560756 DOI=10.3389/fspor.2025.1560756 ISSN=2624-9367 ABSTRACT=IntroductionRunning biomechanics and expected mechanical asymmetries with no history of running-related injuries, and (2) determine whether age influenced gait parameter asymmetry.MethodsThis cross-sectional study included 250 runners were used to test age effects on biomechanical variables and asymmetry outcomes. Effect sizes of age brackets were determined for runner characteristics and biomechanical variables.ResultsRunners aged 55 years had the slowest velocity and 1.7%–4% slower occurred in ankle flexion moments, ankle and knee frontal excursions, and peak VALR (range, 12.1%–33.8% different between right and left limbs).DiscussionGiven that we did not find consistent effects. These data can help inform reference ranges of normative biomechanical metrics and guide clinicians in gait retraining and performance targets across the age spectrum.