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        <title>Frontiers in Stroke | Vascular Cognitive Impairment section | New and Recent Articles</title>
        <link>https://www.frontiersin.org/journals/stroke/sections/vascular-cognitive-impairment</link>
        <description>RSS Feed for Vascular Cognitive Impairment section in the Frontiers in Stroke journal | New and Recent Articles</description>
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        <pubDate>2026-05-13T23:04:42.652+00:00</pubDate>
        <ttl>60</ttl>
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        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fstro.2026.1762758</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fstro.2026.1762758</link>
        <title><![CDATA[NIH Stroke Scale and age predict early post-stroke cognitive impairment]]></title>
        <pubdate>2026-04-28T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Faddi Saleh Velez</author><author>Cameron D. Owens</author><author>Jennifer Hotson</author><author>Andrea Loggini</author><author>Ana Luyza Oliveira Santos</author><author>Demian Rudyk</author><author>Daniela Mercado Pena</author><author>Melba Zuniga-Gutierrez</author><author>Maria Cedeno-Bruzual</author><author>Laura Boada Robayo</author><author>Cheyenne Gutierrez</author><author>Kate Singleton</author><author>Zyanna Stuart</author><author>Evgeny Sidorov</author><author>Andriy Yabluchanskiy</author><author>Camila Bonin Pinto</author>
        <description><![CDATA[IntroductionAcute post-stroke cognitive deficits, which may precede formal post-stroke cognitive impairment (PSCI), lacks evidence-based interventions or guidelines. Up to one-third of PSCI patients progress to dementia within 5 years. Deficits often emerge within 2 weeks, underscoring the need for early recognition of risk factors to guide prevention and management. However, predictive value of demographic, clinical, and stroke-specific factors remains inconsistent. We evaluated cognitive outcomes (Montreal Cognitive Assessment) at discharge and identified predictors of low function.MethodsIn this retrospective study at the University of Oklahoma Medical Center, we reviewed 964 stroke patients, with 168 meeting inclusion criteria. Early PSCI was defined as Montreal Cognitive Assessment < 26 at hospital discharge post-stroke. We calculated prevalence, performed univariable logistic regression, and developed multivariable logistic regression models with and without interaction terms.ResultsPatients with Montreal Cognitive Assessment < 26 were older, had longer hospital stays, higher NIH Stroke Scale, and more often discharged to non-home settings. Prevalence of early PSCI was higher with age, longer stays, non-white race, higher NIH Stroke Scale, and non-home discharge. Univariable analyses revealed length of stay, discharge disposition, NIH Stroke Scale, and race as strongest associations. Final multivariable model (NIH Stroke Scale, age, length of stay, discharge disposition) demonstrated NIH Stroke Scale and age as significant predictors, with good discrimination [Receiver Operating Characteristic-Area Under the Curve (ROC-AUC) = 0.79]. Models including interaction terms performed similarly (ROC-AUC = 0.78).ConclusionConsistent with prior work, NIH Stroke Scale and age emerged as the most robust predictors of early PSCI. Length of stay, discharge disposition, and race were associated with early PSCI in univariable analyses and warrant further evaluation in larger prospective studies.]]></description>
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        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fstro.2024.1450650</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fstro.2024.1450650</link>
        <title><![CDATA[Clinical management of a ruptured intracranial aneurysm]]></title>
        <pubdate>2024-09-24T00:00:00Z</pubdate>
        <category>Review</category>
        <author>Leonidas Trakolis</author><author>Athanasios K. Petridis</author>
        <description><![CDATA[BackgroundIntracranial hemorrhage due to a ruptured aneurysm is one of the most serious neurosurgical emergencies. The patient mostly presents with severe headaches and neurological deterioration. A rapid diagnosis and an interdisciplinary approach play a major role in the fate of these patients. The treatment can vary from endovascular to surgical and must be carefully and individually planned. Neurovascular expertise and an interdisciplinary approach are of vital importance and obligatory for the best possible outcome.MethodsIn this narrative review, we scrutinize the current literature and discuss the actual data and guidelines in order to emphasize the importance of the interdisciplinary expertise and approach in patients with ruptured intracranial aneurysm.ResultsThe current approach to patients with ruptured aneurysm is inhomogeneous and often ineffective due to internal disputes between different disciplines. Although there is plenty of literature and hard evidence to “show the way,” many still choose to base their decisions on personal experience or opinion.ConclusionsEvery ruptured brain aneurysm should be approached in an interdisciplinary manor and treated according to the current evidence and guidelines.]]></description>
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