AUTHOR=Cattaneo Francesco , Motterle Giovanni , Zattoni Filiberto , Morlacco Alessandro , Dal Moro Fabrizio TITLE=The Role of Lymph Node Dissection in the Treatment of Bladder Cancer JOURNAL=Frontiers in Surgery VOLUME=Volume 5 - 2018 YEAR=2018 URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2018.00062 DOI=10.3389/fsurg.2018.00062 ISSN=2296-875X ABSTRACT=Lymph node dissection (LND) is an essential component of radical cystectomy (RC) for bladder cancer. However, the optimal anatomical extent of LND and its potential therapeutic role are still controversial. Moreover, there is large uncertainty on the role of surgery in the setting of patients with clinically-positive nodes. In this review we will provide a synthesis of the available evidence on this highly debated topic.