AUTHOR=Zhang Yue-Xin , Liu Han-Dong , Chen Ze-Hua , Jin Tao , Hu Jian-Kun , Yang Kun TITLE=Comparison of Survival and Safety Between Total Omentectomy and Partial Omentectomy for Gastric Cancer: A Meta-Analysis JOURNAL=Frontiers in Surgery VOLUME=Volume 8 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.708545 DOI=10.3389/fsurg.2021.708545 ISSN=2296-875X ABSTRACT=Background. The greater omentum can limit abdominal inflammation and act as a protective cushion, but it always involves in dissemination of gastric cancer. The purpose of this meta-analysis was to compare the survival and safety between total omentectomy and partial omentectomy for gastric cancer. Methods. Two investigators independently conducted a systematic search of PubMed, Embase, CNKI and Cochrane Library ranging from January 2000 to November 2020. The pooled odds ratio (ORs) and weighted mean difference (WMD) with the 95% confidence interval (95% CI) were used to assess perioperative and survival parameters. Results. A total of 2031 patients in eleven studies (574 patients in the partial omentectomy group and 1457 patients in the total omentectomy group) were included. The results found shorter operation time (WMD=-25.584; P=0.000) and less intraoperative blood loss (WMD=-47.301; P=0.050) in the partial omentectomy group, compared to total omentectomy. There were no significant differences in terms of incidence of complications (OR=0.770; P=0.164), blood transfusions rates (OR=0.269; P=0.161), time to first flatus (WMD=0.160; P=0.345), hospital stay (WMD=-1.258; P=0.087) and number of harvested lymph nodes (WMD=1.265; P=0.662). For the disease-free survival (OR=0.80; P=0.381) and overall survival, there were no statistical difference between the two procedures. Conclusions. The partial omentectomy could reduce the operation time and trended to decrease intraoperative blood loss. And the survival in patients with partial omentectomy seemed to be comparable to that of patients with total omentectomy.