AUTHOR=Zhang Jia , Wang Miye , Xin Zechang , Li Ping , Feng Qingbo 

TITLE=Updated Evaluation of Laparoscopic vs. Open Appendicectomy During Pregnancy: A Systematic Review and Meta-Analysis

JOURNAL=Frontiers in Surgery

VOLUME=Volume 8 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.720351

DOI=10.3389/fsurg.2021.720351

ISSN=2296-875X

ABSTRACT=To explore the updated evaluation about the obstetrical and perioperative outcomes of laparoscopic appendicectomy (LA) for pregnancy appendicitis compared to the open appendicectomy (OA). Two reviewers independently searched the PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, and Web of Science databases to screen eligible studies up to Dec. 2020. Only clinical researches no less than 10 cases for LA and OA group were included. Twenty retrospective studies with 7248 pregnant women, evaluating LA and OA in surgical and obstetrical outcomes were included. The weighted mean difference (WMD) with the 95% confidence interval (CI) and odds ratio (OR) were severally used to compare continuous and dichotomous variables. It seems LA was connected with significantly shorter hospital time and lower wound infection［mean difference (MD), -0.57 days; 95% confidence interval (CI), -0.96 to -0.18; p=0.004 and odds ratio (OR), 0.34; 95% CI, 0.18 to 0.62; p=0.0005, respectively］.The incidence of fetal loss after LA was higher than OA (OR,1.93; 95% CI, 1.39 to 2.69; p＜0.0001), It was almost similar in the rate of preterm delivery (OR, 0.80; 95% CI, 0.48 to 1.34; p=0.40) and other perioperative and obstetrical complications (P>0.05). Our results indicated that the occurrence of fetal loss after LA should not be ignored. Caution, skillful operation and thoroughly informed consent about the advantages and disadvantages of laparoscopy are necessary.