AUTHOR=Jin Yang , Xiong Hui , Xia Qinghua , Zhang Qi 

TITLE=A Modified Two-Layer Suture Technique for Transperitoneal Laparoscopic Partial Nephrectomy: Single-Center Clinical Experience

JOURNAL=Frontiers in Surgery

VOLUME=Volume 8 - 2021

YEAR=2022

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.761090

DOI=10.3389/fsurg.2021.761090

ISSN=2296-875X

ABSTRACT=Purposes: This study aims to evaluate the feasibility and efficacy of a modified two-layer suture method during laparoscopic partial nephrectomy (LPN), by a comparative analysis with the traditional two-layer suture.
Methods: A total of 60 LPN patients were enrolled in this study, of which 30 patients received the modified two-layer suture method and the remaining 30 patients underwent the traditional two-layer suture. Then, surgical characteristics including operative time, warm ischemic time (WIT), estimated blood loss/EBL, glomerular filtration rate (GFR) were recorded. Finally, univariable and multivariable linear regression analyses were used to evaluate the correlations of tumor characteristics, suture methods, and postoperative renal function.
Results: There was no significant difference between two suture groups with respect to patient and tumor characteristics, postoperative creatinine level and blood urea nitrogen (BUN) level. The modified suture group showed a significantly shorter clamping time and a less GFR level reduction than the traditional two-layer suture group (15 min versus 23 min; 42.32 ± 9.48 versus 27.07 ± 7.88; P < 0.05). Additionally, the modified two-layer suture was an independent factor that influenced the clamping time and the level of GFR reduction.
Conclusion: The modified two-layer suture method is feasible and effective for LPN.