AUTHOR=Zhao Bin , Mao Jie , Li Yumin 

TITLE=Primary hepatic neuroendocrine tumor associated with hypertension: A case report

JOURNAL=Frontiers in Surgery

VOLUME=Volume 9 - 2022

YEAR=2023

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2022.1021806

DOI=10.3389/fsurg.2022.1021806

ISSN=2296-875X

ABSTRACT=Background: Primary neuroendocrine tumors are exceedingly rare and often  misdiagnosed. The combined methods of ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI) are typically applied. The diagnosis of the  disease mainly depends on the histopathological examination. Surgical resection is the  most effective treatment. 
Case presentation: In the report, we describe the case of a patient with a primary  hepatic neuroendocrine tumor (PHNET) associated with hypertension. The patient   suffered from uncontrolled hypertension before the operation, and the blood pressure was not well controlled by oral antihypertensive drugs such as nifedipine, valsartan and hydrochlorothiazide, but the patient's blood pressure completely returned to  normal after the operation.  
Conclusions: We encountered a rare case of a PHNET associated with  hypertension via careful screening noticed by the patient at work; furthermore, we hope to collect more cases  and find the relationship between neuroendocrine tumors and hypertension.