AUTHOR=Ielpo Benedetto , Podda Mauro , Burdio Fernando , Sanchez-Velazquez Patricia , Guerrero Maria-Alejandra , Nuñez Javier , Toledano Miguel , Morales-Conde Salvador , Mayol Julio , Lopez-Cano Manuel , Espín-Basany Eloy , Pellino Gianluca , The ROBOCOSTES Study Collaborators , Momblan Dulce , Castro Boix Sandra , Cugat Esteban , pardo , Pujadas Marcel , Jorba Rosa , Luque Juan Bellido , Cagigas Carmen , Trebol Jacobo , Olmo Juan Carlos Martín del , García Helena Álvarez , Rodríguez José Herreros , Fernández Silva , Guillen Luis Sanchez , Aguilar José Francisco Noguera , Santos Raquel Sánchez , Sampedro Juan José Segura , Mérdia Ma Asuncion Acosta , González Iván Jesús Arteaga , Vázquez Irene Ortega , Gallego Mario Álvarez , Vicente Emilio , Cortijo Sagrario Martinez , Pizarro Sergio Pedro Olivares , Luengas David Fernandez , Jiménez David Alías , González-Abós Carolina , Gantxegi Amaia , Bassols Clara Codony , Agua Isaias Alarcon del , Maag Carlos Rafael Díaz , Amo Aroa Abascal , Fernández Carlos Jezieniecki , Sánchez David Pacheco , Orozco Julián García , Ortiz Beatriz Guil , Lasaia Manuel Alberto , Ríos Raquel , Gómez Jorge Zárate , García Gustavo Díaz , Rodrígues Víctor , Conde Guillermo Ais , Celemín Esther Ferrero , Linacero Santiago , Josa Miguel , Pascual Marta , Carré Miquel Kraft , Giné Pere Planellas , González Javier Sánchez , López Alberto Rojo , Quintana Rita Medina , Morante Ana Pilar , Ausania Fabio , Pando Elisabeth , López-Ben Santiago , García Ángel Cuadrado , Pereira José Antonio , Bravo Alex , Rentería Juan Beltrán de Heredia , López Daniel Sánchez , Casajoana Anna , Puy Ramón Vilallonga , Sancho Luis García , O‘Reilly María Hernández , López and José María Gil TITLE=Cost-Effectiveness of Robotic vs. Laparoscopic Surgery for Different Surgical Procedures: Protocol for a Prospective, Multicentric Study (ROBOCOSTES) JOURNAL=Frontiers in Surgery VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2022.866041 DOI=10.3389/fsurg.2022.866041 ISSN=2296-875X ABSTRACT=Background The studies which address the impact of costs of robotic vs laparoscopic approach on quality of life (cost-effectiveness studies) are scares in general surgery. Methods The Spanish national study on cost-effectiveness differences among robotic and laparo-scopic surgery (ROBOCOSTES) is designed as a prospective, multicentre, national, obser-vational study. The aim is to determine in which procedures robotic surgery is more cost-effective than laparoscopic surgery. Several surgical operations and patient populations will be evaluated (distal pancreatectomy, gastrectomy, sleeve gastrectomy, inguinal hernioplasty, rectal re-section for cancer, Heller cardiomiotomy and Nissen procedure). Discussion The results of this study will demonstrate which treatment (laparoscopic or robotic) and in which population is more cost-effective. This study will also assess the impact of previous surgical experience on main outcomes.