AUTHOR=萍 梁 , 雅晳 王 , 鑫 李 , 志刚 程 , 杰 于 , 启迪 侯 

TITLE=Prognostic Nutritional Index in Hepatocellular Carcinoma Patients With Hepatitis B Following US-Guided Percutaneous Microwave Ablation: A Retrospective Study With 1,047 Patients

JOURNAL=Frontiers in Surgery

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2022.878737

DOI=10.3389/fsurg.2022.878737

ISSN=2296-875X

ABSTRACT=Abstract
Objective: Several studies have revealed that prognostic nutritional index (PNI) was associated with survival in several cancers. However, the prognostic value of PNI in hepatocellular carcinoma (HCC) patients followed ultrasound-guided percutaneous microwave ablation (US-PMWA) remains unknown, especially in patients with hepatitis B virus (HBV) infection. So, the present study aimed to evaluate the potential prognostic value of PNI in these patients.
Materials: The medical records of 1047 HCC patients with HBV infection followed US-PMWA were retrospectively reviewed. The association between preoperative PNI and overall survival (OS), as well as clinical characteristics of HCC, were analyzed using the Kaplan-Meier plot, log-rank test, multi-parameter Cox proportional hazards model, restricted cubic spline (RCS) and time-dependent receiver operating characteristic (ROC) curves analysis