AUTHOR=Zhao Shouwen , Song Yuanyuan , Zhang Le , Shi Sunan , Li Jie , Ma Yuping , Liao Yong , Zhen Zhongguang 

TITLE=Anticipating postoperative complications in hepatobiliary surgery: procalcitonine as predictive factor

JOURNAL=Frontiers in Surgery

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2025.1564843

DOI=10.3389/fsurg.2025.1564843

ISSN=2296-875X

ABSTRACT=Background and aimsFew studies have indicated that procalcitonin has a potential role in anticipating postoperative complications of hepatic surgery. Here, we focused on validating the relationship between posthepatectomy and serum procalcitonin as short-term prognostic factors.MethodsData from 52 patients who underwent hepatectomy (partial) due to hepatocellular carcinoma from June 2018 to July 2023 were enrolled to evaluate the risk factors related to post-hepatectomy complications, especially post-hepatectomy liver failure and 30-day survival.Results52 patients were included in the study, and their data was analyzed for PCT. 21 showed raised PCT (>1 ng/ml). Results showed a significant association of PCT with post-hepatectomy liver failure, and the same is associated with 30-day mortality in ICU-admitted patients.ConclusionElevated PCT levels in patients after hepatic surgery are associated with poor prognosis and could be used as a potential predictive factor.