AUTHOR=Wu Chenrui , Tian Yu , Zhao Ruichen , Chen Runfang , Xu Chuanlin , Huang Jinsheng , Jiang Rongcai 

TITLE=Conservative therapy of epidural hematoma with atorvastatin combined with glucocorticoids: cases report and literature review

JOURNAL=Frontiers in Surgery

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2025.1587988

DOI=10.3389/fsurg.2025.1587988

ISSN=2296-875X

ABSTRACT=Epidural hematomas (EDH), typically requiring surgery, may be managed conservatively in select patients. We investigated atorvastatin (10 mg/day) combined with dexamethasone (2.25 mg/day) as conservative therapy in six EDH patients (GCS ≥ 13, volume < 30 ml) post-trauma. All patients recovered fully without surgery, and literatures support conservative care for stable EDH. Our findings suggest this combination therapy may promote hematoma absorption. In conclusion, atorvastatin/dexamethasone shows promise as a non-surgical EDH option, warranting further investigation.