AUTHOR=Mukherjee Rajib TITLE=Reliability-Based Robust Multi-Objective Optimization (RBRMOO) of Chemical Process Systems: A Case Study of TEG Dehydration Plant JOURNAL=Frontiers in Sustainability VOLUME=Volume 3 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/sustainability/articles/10.3389/frsus.2022.856836 DOI=10.3389/frsus.2022.856836 ISSN=2673-4524 ABSTRACT=Natural gas (NG) production has significantly increased in the past decade as new unconventional oil and gas wells are being discovered. NG as obtained from the wellhead requires processing before being considered as pipeline grade. The process consists of the removal of acidic gases followed by dehydration. NG processing is associated with toxic emission having substantial environmental and health impact. Difficulty in NG processing arises from varied flow rate and uncertain feed composition that provides a challenge in efficient design as well as finding the optimal operating condition. In this work, a stochastic approach is used to characterize natural gas composition and its importance on the product and waste emission is studied. Under the uncertain feed composition, optimal operating condition of the controllable variables was attained by a reliability-based robust multi-objective optimization (RBRMOO) technique that mitigates BTEX emission while fulfilling NG pipeline specification. Chemical process simulator is used to obtain the correlation between the control process settings and the variation in the uncertain feed condition with regard to NG dehydration and BTEX emission. The best prediction models were developed using machine learning algorithm, chosen from a family of metamodels. RBRMOO is performed using metaheuristic algorithm to determine the optimal process condition of the control variables. The impact of uncertain feed composition in process modeling and subsequent optimization demonstrates optimal process condition where the rate of emission is lower by approximately 83 ton/yr when compared to that from the deterministic model where median value of uncertain feed composition is used for analysis, portraying the limitations of traditional sustainability assessment methods that do not account for uncertainty.