Frontiers in Systems Biology | Data and Model Integration section | New and Recent Articles https://www.frontiersin.org/journals/systems-biology/sections/data-and-model-integration RSS Feed for Data and Model Integration section in the Frontiers in Systems Biology journal | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-14T18:32:31.566+00:00 60 https://www.frontiersin.org/articles/10.3389/fsysb.2026.1729027 https://www.frontiersin.org/articles/10.3389/fsysb.2026.1729027 <![CDATA[Mathematical modeling of bone remodeling after surgical menopause]]> 2026-02-11T00:00:00Z Original Research Anna C. NelsonEdwina F. YeoYun ZhangCarley V. CookSophie Fischer-HolzhausenLauryn Keeler BrucePritha DuttaSamaneh GholamiBrenda J. SmithAshlee N. Ford Versypt https://www.frontiersin.org/articles/10.3389/fsysb.2025.1651930 https://www.frontiersin.org/articles/10.3389/fsysb.2025.1651930 <![CDATA[BioMedKG: multimodal contrastive representation learning in augmented BioMedical knowledge graphs]]> 2025-12-08T00:00:00Z Original Research Tien DangViet Thanh Duy NguyenMinh Tuan LeTruong-Son Hy https://www.frontiersin.org/articles/10.3389/fsysb.2025.1656683 https://www.frontiersin.org/articles/10.3389/fsysb.2025.1656683 <![CDATA[The role of neutrophil-to-lymphocyte ratio in the prognosis of chronic kidney disease: insights from the NHANES cohort study]]> 2025-10-27T00:00:00Z Original Research Ying LiuRu WangJinguo YuanJin Zhao https://www.frontiersin.org/articles/10.3389/fsysb.2025.1717030 https://www.frontiersin.org/articles/10.3389/fsysb.2025.1717030 <![CDATA[Correction: A guide to bayesian networks software for structure and parameter learning, with a focus on causal discovery tools]]> 2025-10-23T00:00:00Z Correction Francesco CanonacoJoverlyn GaudilloNicole AstrologoFabio StellaEnzo Acerbi https://www.frontiersin.org/articles/10.3389/fsysb.2025.1649758 https://www.frontiersin.org/articles/10.3389/fsysb.2025.1649758 <![CDATA[GETgene-AI: a framework for prioritizing actionable cancer drug targets]]> 2025-09-29T00:00:00Z Original Research Adrian GuJake Y. Chen https://www.frontiersin.org/articles/10.3389/fsysb.2025.1631901 https://www.frontiersin.org/articles/10.3389/fsysb.2025.1631901 <![CDATA[A guide to bayesian networks software for structure and parameter learning, with a focus on causal discovery tools]]> 2025-08-25T00:00:00Z Mini Review Francesco CanonacoJoverlyn GaudilloNicole AstrologoFabio StellaEnzo Acerbi https://www.frontiersin.org/articles/10.3389/fsysb.2025.1589079 https://www.frontiersin.org/articles/10.3389/fsysb.2025.1589079 <![CDATA[Learning Gaussian graphical models from correlated data]]> 2025-07-03T00:00:00Z Methods Zeyuan SongSophia GunnStefano MontiGina M. PelosoChing-Ti LiuKathryn LunettaPaola Sebastiani https://www.frontiersin.org/articles/10.3389/fsysb.2024.1500710 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1500710 <![CDATA[Improvement in the prediction power of an astrocyte genome-scale metabolic model using multi-omic data]]> 2025-01-03T00:00:00Z Original Research Andrea Angarita-RodríguezNicolás Mendoza-MejíaJanneth GonzálezJason PapinAndrés Felipe AristizábalAndrés Pinzón https://www.frontiersin.org/articles/10.3389/fsysb.2024.1470000 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1470000 <![CDATA[Intertwined roles for GDF-15, HMGB1, and MIG/CXCL9 in Pediatric Acute Liver Failure]]> 2024-10-15T00:00:00Z Original Research Ruben ZamoraJinling YinDerek BarclayJames E. SquiresYoram Vodovotz https://www.frontiersin.org/articles/10.3389/fsysb.2024.1419809 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1419809 <![CDATA[Spectral expansion methods for prediction uncertainty quantification in systems biology]]> 2024-10-03T00:00:00Z Methods Anna DeneerJaap MolenaarChristian Fleck https://www.frontiersin.org/articles/10.3389/fsysb.2024.1283371 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1283371 <![CDATA[Accessible Type 2 diabetes medication through stable expression of Exendin-4 in Saccharomyces cerevisiae]]> 2024-09-02T00:00:00Z Original Research Gia BaliusKiana ImaniZoë PetroffElizabeth BeerThiago Brasileiro FeitosaNathan MccallLauren PauleNeo Yixuan PengJoanne ShenVidhata SinghCambell StrandJonathan ZauD. L. Bernick https://www.frontiersin.org/articles/10.3389/fsysb.2024.1407994 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1407994 <![CDATA[The rise of scientific machine learning: a perspective on combining mechanistic modelling with machine learning for systems biology]]> 2024-08-02T00:00:00Z Review Ben NoordijkMonica L. Garcia GomezKirsten H. W. J. ten TusscherDick de RidderAalt D. J. van DijkRobert W. Smith https://www.frontiersin.org/articles/10.3389/fsysb.2024.1394084 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1394084 <![CDATA[Transporter annotations are holding up progress in metabolic modeling]]> 2024-07-24T00:00:00Z Perspective John CaseyBrian BennionPatrik D’haeseleerJeffrey KimbrelGianna MarschmannAli Navid https://www.frontiersin.org/articles/10.3389/fsysb.2024.1377188 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1377188 <![CDATA[Surface-displayed silicatein-α enzyme in bioengineered E. coli enables biocementation and silica mineralization]]> 2024-05-30T00:00:00Z Original Research Toriana N. VigilNikolas K. SchwendemanMelanie L. M. GroggerVictoria L. MorrisonMargaret C. WarnerNathaniel B. BoneMorgan T. VanceDavid C. MorrisKristi McElmurryBryan W. BergerJ. Jordan Steel https://www.frontiersin.org/articles/10.3389/fsysb.2024.1308292 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1308292 <![CDATA[Context-aware knowledge selection and reliable model recommendation with ACCORDION]]> 2024-04-18T00:00:00Z Technology and Code Yasmine AhmedCheryl A. TelmerGaoxiang ZhouNatasa Miskov-Zivanov https://www.frontiersin.org/articles/10.3389/fsysb.2024.1284668 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1284668 <![CDATA[Forecasting SARS-CoV-2 spike protein evolution from small data by deep learning and regression]]> 2024-04-09T00:00:00Z Original Research Samuel KingXinyi E. ChenSarah W. S. NgKimia RostinSamuel V. HahnTylo RobertsJanella C. SchwabParneet SekhonMadina KagievaTaylor ReillyRuo Chen QiPaarsa SalmanRyan J. HongEric J. MaSteven J. Hallam https://www.frontiersin.org/articles/10.3389/fsysb.2024.1367562 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1367562 <![CDATA[In silico biomarker analysis of the adverse effects of perfluorooctane sulfonate (PFOS) exposure on the metabolic physiology of embryo-larval zebrafish]]> 2024-03-27T00:00:00Z Original Research Rayna M. NolenLene H. PetersenKarl KaiserAntonietta QuiggDavid Hala https://www.frontiersin.org/articles/10.3389/fsysb.2024.1335885 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1335885 <![CDATA[Computational insights in cell physiology]]> 2024-03-13T00:00:00Z Mini Review Geneviève DupontDidier Gonze https://www.frontiersin.org/articles/10.3389/fsysb.2024.1333760 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1333760 <![CDATA[Integrating inverse reinforcement learning into data-driven mechanistic computational models: a novel paradigm to decode cancer cell heterogeneity]]> 2024-03-08T00:00:00Z Perspective Patrick C. KinnunenKenneth K. Y. HoSiddhartha SrivastavaChengyang HuangWanggang ShenKrishna GarikipatiGary D. LukerNikola BanovicXun HuanJennifer J. LindermanKathryn E. Luker https://www.frontiersin.org/articles/10.3389/fsysb.2024.1363884 https://www.frontiersin.org/articles/10.3389/fsysb.2024.1363884 <![CDATA[BioModels’ Model of the Year 2023]]> 2024-02-27T00:00:00Z Perspective Rahuman S. Malik SheriffHiroki AsariHenning HermjakobWolfgang HuberThomas QuailSilvia D. M. SantosAmber M. SmithVirginie Uhlmann