AUTHOR=Zare Jeddi Maryam , Galea Karen S. , Viegas Susana , Fantke Peter , Louro Henriqueta , Theunis Jan , Govarts Eva , Denys Sébastien , Fillol Clémence , Rambaud Loïc , Kolossa-Gehring Marike , Santonen Tiina , van der Voet Hilko , Ghosh Manosij , Costa Carla , Teixeira João Paulo , Verhagen Hans , Duca Radu-Corneliu , Van Nieuwenhuyse An , Jones Kate , Sams Craig , Sepai Ovnair , Tranfo Giovanna , Bakker Martine , Palmen Nicole , van Klaveren Jacob , Scheepers Paul T. J. , Paini Alicia , Canova Cristina , von Goetz Natalie , Katsonouri Andromachi , Karakitsios Spyros , Sarigiannis Dimosthenis A. , Bessems Jos , Machera Kyriaki , Harrad Stuart , Hopf Nancy B. 

TITLE=FAIR environmental and health registry (FAIREHR)- supporting the science to policy interface and life science research, development and innovation

JOURNAL=Frontiers in Toxicology

VOLUME=Volume 5 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2023.1116707

DOI=10.3389/ftox.2023.1116707

ISSN=2673-3080

ABSTRACT=The environmental impact on health is an inevitable by-product of human activity. Environmental health sciences (EHS) is a multidisciplinary field addressing complex issues on how people are exposed to hazardous chemicals that can potentially affect adversely the health of present and future generations. Exposure sciences and environmental  epidemiology are becoming increasingly data-driven and their efficiency and effectiveness can significantly improve by implementing the FAIR (findable, accessible, interoperable, reusable) principles for scientific data management and stewardship. This will enable data integration, interoperability and (re)use while also facilitating the use of new and powerful analytical tools such as artificial intelligence and machine learning in the benefit of public health policy, and research and development (R&D). Early research planning is critical to ensuring data is FAIR at the outset. This includes an informed strategy about what data and metadata to collect, how it will be collected and documented, and approaches for assessing its quality and management. Therefore, the ‘Europe Regional Chapter of the International Society of Exposure Science’ (ISES Europe) human biomonitoring working group (HBM WG) proposes the development of a FAIR Environmental health registry (FAIREHR) (hereafter FAIREHR). FAIREHR offers preregistration of  studies on exposure sciences and environmental epidemiology using HBM (as a starting point) across all areas of environmental and occupational health globally. The registry is proposed to receive a dedicated web-based interface, to be electronically searchable and to be available to all relevant data providers, users and stakeholders. Planned HBM studies would ideally be registered before formal recruitment of study participants. The resulting FAIREHR would contain public records of metadata such as study design, data management, an audit trail of major changes to planned methods, details of when the study will be completed, and links to resulting publications and data repositories when provided by the authors. The FAIREHR would be an integrated service for scientists, life sciences companies, publishers, and policy makers with user-friendly features and enable science to provide much better understanding of health-stressor relationships through more effective use of HBM data.