Frontiers in Toxicology

Original Research

Published on 28 Oct 2025

A toxicological assessment of Hericium erinaceus (Lion’s mane) and Trametes versicolor (Turkey tail) mushroom powders

in Food and Nutritional Toxicology

Kritika Mahadevan
Julie Daoust
Thomas Brendler
Ankit Chaudhary
Alimuddin Saifi
Vipin Kumar Garg

Frontiers in Toxicology

doi 10.3389/ftox.2025.1651442

4,269 views
2 citations

Original Research

Published on 20 Oct 2025

Toxicological and nutritional evaluation of plant cell cultures from scurvy grass (Cochlearia danica) and rowan (Sorbus aucuparia)

in Food and Nutritional Toxicology

Felicianna
Ho Lam Cheung
Emily Kwun Kwan Lo
Fangfei Zhang
Hoi Kit Matthew Leung
Marsena Jasiel Ismaiah
Natalia Rosa-Sibakov
Valeria Iannone
Carlos Gómez-Gallego
Marjukka Kolehmainen

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655489

1,836 views
1 citation

Original Research

Published on 20 Oct 2025

Toxicological effects of sublethal microcystin-LR exposure in Labeo rohita: histopathological, ultrastructural, immunological, and biochemical impairments

in Environmental Toxicology

Snatashree Mohanty
Anirban Paul
K. V. Rajendran
Gayatri Tripathi
Pratap Chandra Das
Pramoda Kumar Sahoo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1658995

1,575 views

Original Research

Published on 17 Oct 2025

Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish

in Neurotoxicology

Lindsey St. Mary
Ryan McClure
Lisa Truong
Steven J. Carrell
Katrina M. Waters
Robyn L. Tanguay

Frontiers in Toxicology

doi 10.3389/ftox.2025.1675060

1,784 views

Original Research

Published on 17 Oct 2025

Danger on the plate: human health risks derived from the consumption of angular angelshark (Squatina guggenheim) meat in southeastern Brazil

in Food and Nutritional Toxicology

Amanda Pontes Lopes
Rebeca Dias de Souza Coutinho
Tatiana Dillenburg Saint’Pierre
Rachel Ann Hauser-Davis

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645858

1,496 views

Original Research

Published on 15 Oct 2025

A short-term sublethal oral exposure to microcystin-LR disrupts cecal microbiome homeostasis in mallard

in Environmental Toxicology

Serguei V. Drovetski
Valerie I. Shearn-Bochsler
Erik K. Hofmeister
Natalie K. Karouna-Renier
Robert J. Dusek

Frontiers in Toxicology

doi 10.3389/ftox.2025.1634241

1,170 views

Original Research

Published on 14 Oct 2025

Intravenously administered iron oxide nanoparticles with different coatings reversibly perturb immune cells in peripheral blood without inducing toxicity in mice

in Nanotoxicology

Preethi Korangath
Chun-Ting Yang
Sean Healy
Cordula Grüttner
Kathleen Gabrielson
Robert Ivkov

Frontiers in Toxicology

doi 10.3389/ftox.2025.1673416

1,647 views

Perspective

Published on 13 Oct 2025

Refining the safety assessment of newly expressed proteins in GMOs

in In Vitro Toxicology

Elena Sánchez-Brunete
Arianna Ferrari
F. Javier Moreno
Tilemachos Goumperis
Michele Ardizzone
Reinhilde Schoonjans
Ian Dewhurst
Ivan Dimitrov
Michelle M. Epstein
Frits Koning

Frontiers in Toxicology

doi 10.3389/ftox.2025.1679506

2,235 views

Original Research

Published on 08 Oct 2025

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

in Regulatory Toxicology

Jessica Ryman
Richard A. Becker

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657708

1,835 views

Review

Published on 07 Oct 2025

Advancing human health risk assessment: the role of new approach methodologies

in Computational Toxicology and Informatics

Deepika Deepika
Kanchan Bharti
Shubh Sharma
Saurav Kumar
Rajesh Kumar Pathak
Judit Biosca Brull
Oscar Sabuz
Silvia García Vilana
Vikas Kumar

Frontiers in Toxicology

doi 10.3389/ftox.2025.1632941

3,504 views
3 citations

Review

Published on 03 Oct 2025

Pesticides, an urgent challenge to global environmental health and planetary boundaries

in Developmental and Reproductive Toxicology

Laura N. Vandenberg
Elise J. Pierce
Rachel M. Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

3,990 views
2 citations

Original Research

Published on 03 Oct 2025

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays

in In Vitro Toxicology

Agnes L. Karmaus
Alex Charlton

Frontiers in Toxicology

doi 10.3389/ftox.2025.1682439

1,327 views

Original Research

Published on 01 Oct 2025

Hospital admissions for acute drug poisoning in adults and children: a 7-year retrospective analysis of hospital discharges at a tertiary center

in Clinical Toxicology

Daniel Wang
Lina Camacho-Arteaga
Rosario Muñoz Gallarín
Immaculada Danés
Antònia Agustí Escasany

Frontiers in Toxicology

doi 10.3389/ftox.2025.1672470

1,961 views

Original Research

Published on 01 Oct 2025

Proliferation and metabolic activity of the Atlantic sturgeon cell line AOXlar7y under short-term serum-reduced conditions, and the effect of stimulation with growth factors and cytokines

in In Vitro Toxicology

Valeria Di Leonardo
Julia Brenmoehl
Heike Wanka
Bianka Grunow

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636776

1,714 views

Original Research

Published on 01 Oct 2025

Promoting ethical and reproducible cell culture: implementing animal-free alternatives to teaching in molecular and cell biology

in In Vitro Toxicology

Alexandra Nessar
Viola Röhrs
Mathias Ziersch
Ahmed S. M. Ali
Julia Moradi
Anke Kurreck
Johanna Berg
Jens Kurreck

Frontiers in Toxicology

doi 10.3389/ftox.2025.1670513

4,762 views
1 citation

Original Research

Published on 30 Sep 2025

Acetaldehyde and methylglyoxal: comparative analysis of toxic electronic cigarette degradation products in 3D and 2D exposure systems using human bronchial epithelial models

in In Vitro Toxicology

Man Wong
Teresa Martinez
Nathan Hendricks
Prue Talbot

Frontiers in Toxicology

doi 10.3389/ftox.2025.1624794

4,373 views

Original Research

Published on 29 Sep 2025

In Vitro analysis of the effect of mono-(2-ethylhexyl) phthalate (MEHP) exposure on macrophage inflammatory responses in relationship to Leydig cell steroid production

in Developmental and Reproductive Toxicology

Akhil Adla
Allison Lunney
Barry Zirkin
Kassim Traore

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636395

1,771 views

Review

Published on 29 Sep 2025

Excessive alcohol consumption: a driver of metabolic dysfunction and inflammation

in Food and Nutritional Toxicology

Jaeeun Lee
Ji-Young Lee
Hyunju Kang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1670769

7,943 views
5 citations

Original Research

Published on 26 Sep 2025

From genes to organs: physiological responses of European chub (Squalius cephalus) to chronic PFAS pollution

in Environmental Toxicology

Sara Pacchini
Laura Drago
Martina Cortese
Giacomo Vanzan
Elisabetta Piva
Shaghayegh Kholdihaghighi
Andrea Barbarossa
Anisa Bardhi
Sophia Schumann
Chiara Fogliano

Frontiers in Toxicology

doi 10.3389/ftox.2025.1654272

1,854 views

Original Research

Published on 25 Sep 2025

Implementing a trilineage differentiation in the ReproTracker assay for improved teratogenicity assessment

in Developmental and Reproductive Toxicology

José M. Horcas-Nieto
Sabine Hartvelt
Luke Flatt
Jing Fang
Esther Lam
Gaonan Zhang
Romy Van Vliet
Marleen Feliksik
Tom Zwetsloot
Connor Philippo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645842

2,923 views

Mini Review

Published on 25 Sep 2025

Forensic toxicology of benzodiazepines: neuropharmacological effects, analytical challenges, and emerging detection strategies

in Clinical Toxicology

Husna Irfan Thalib
Ahmed Abdelghany Damanhory
Ayesha Hanin Shaikh
Shyma Haidar
Sariya Khan
Ayesha Jamal
Omar Ahmed Abdelghany

Frontiers in Toxicology

doi 10.3389/ftox.2025.1639890

4,729 views
1 citation

Review

Published on 19 Sep 2025

Environmental exposure pathways of microplastics and their toxic effects on ecosystems and the nervous system

in Neurotoxicology

Kuo Lu
Yixiang Que
Longfei Wang
Yanfan Wang
Jinyan Qiu
Yangyang Jia
Cong Ding
Dazhong Wang
Weyland Cheng
Yaodong Zhang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1649282

3,932 views
1 citation

Original Research

Published on 15 Sep 2025

Error-corrected next-generation sequencing mutagenicity assays in human HepaRG cells as human-relevant genetic toxicology new approach methodology

in Regulatory Toxicology

A. Rasim Barutcu
Nimisha Bhattarai
Raymond Samuel
Jamie Scaglione
Leslie Recio

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657189

2,521 views
1 citation

Original Research

Published on 15 Sep 2025

Daflon and Centrum mitigate vancomycin-induced nephrotoxicity in rats by ameliorating oxidative stress, DNA damage, apoptosis, and inflammation

in Clinical Toxicology

Hanem F. El-Gendy
Soaad Salamah
Eman Elhusseiny
Hazim O. Khalifa
Hossny A. El-Banna
Taha A. Attia
Shaimaa Selim
Saber El Hanbally

Frontiers in Toxicology

doi 10.3389/ftox.2025.1673083

1,663 views