Frontiers in Toxicology | Developmental and Reproductive Toxicology

Systematic Review

Accepted on 17 Oct 2025

Endocrine Disruption Rewards: Bisphenol-A-Induced Reproductive Toxicity and the Precision Ameliorative Potential of Flavonoids in Preclinical Studies. A Systematic Review and Meta-Analysis

in Developmental and Reproductive Toxicology

Michael Ben Okon
ILEMOBAYO VICTOR FASOGBON
Dominic Terkimbi Swase
Reuben Samson Dangana
Wusa Makena
Vivian Onyinye Ojiakor
Monday Ekom Etukudo
Joan Chebet
Angela Mumbua Musyoka
Sandra Etumah Ifie

Frontiers in Toxicology

doi 10.3389/ftox.2025.1687862

Review

Published on 03 Oct 2025

Pesticides, an urgent challenge to global environmental health and planetary boundaries

in Developmental and Reproductive Toxicology

Laura N. Vandenberg
Elise J. Pierce
Rachel M. Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

986 views

Original Research

Published on 29 Sep 2025

In Vitro analysis of the effect of mono-(2-ethylhexyl) phthalate (MEHP) exposure on macrophage inflammatory responses in relationship to Leydig cell steroid production

in Developmental and Reproductive Toxicology

Akhil Adla
Allison Lunney
Barry Zirkin
Kassim Traore

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636395

835 views

Original Research

Published on 25 Sep 2025

Implementing a trilineage differentiation in the ReproTracker assay for improved teratogenicity assessment

in Developmental and Reproductive Toxicology

José M. Horcas-Nieto
Sabine Hartvelt
Luke Flatt
Jing Fang
Esther Lam
Gaonan Zhang
Romy Van Vliet
Marleen Feliksik
Tom Zwetsloot
Connor Philippo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1645842

1,345 views

Hypothesis and Theory

Published on 21 Aug 2025

Determining a NOAEL for the consortium linking academic and regulatory insights on BPA toxicity (CLARITY-BPA) core study

in Developmental and Reproductive Toxicology

Melissa Badding
Noor Aly
Kevin Sondenheimer

Frontiers in Toxicology

doi 10.3389/ftox.2025.1639737

1,330 views

Original Research

Published on 30 Jun 2025

An advancement in developmental and reproductive toxicity (DART) risk assessment: evaluation of a bioactivity and exposure-based NAM toolbox

in Developmental and Reproductive Toxicology

Iris Mueller
Ashraf Abdelkhaliq
Paul Carmichael
Matthew Dent
Marleen Feliksik
Luke Flatt
Jade Houghton
José M. Horcas Nieto
Amer Jamalpoor
Predrag Kukic

Frontiers in Toxicology

doi 10.3389/ftox.2025.1602065

4,690 views
1 citation

Original Research

Published on 21 May 2025

Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina

in Developmental and Reproductive Toxicology

Florencia Doná
Virginia Lorenz
Georgina Stegmayer
Tamara Ricardo
Stefanía D’Iorio
Fernando Ponzo
María Rosa Repetti
Luisina Delma Demonte
María Mercedes Milesi
Jorgelina Varayoud

Frontiers in Toxicology

doi 10.3389/ftox.2025.1579952

2,928 views

Original Research

Published on 08 May 2025

Rat embryonic stem cell-based in vitro testing platform for mammalian embryo toxicology at pre- and post-implantation stages

in Developmental and Reproductive Toxicology

Corinne Quadalti
Marzia Moretti
Fabio Ferrazzi
Laura Calzà
Luciana Giardino
Vito Antonio Baldassarro

Frontiers in Toxicology

doi 10.3389/ftox.2025.1561386

2,091 views

Perspective

Published on 13 Mar 2025

Pesticides and public health: discussing risks in Brazilian agro-industrial growth

in Developmental and Reproductive Toxicology

Juliana E. Perobelli

Frontiers in Toxicology

doi 10.3389/ftox.2025.1442801

8,299 views
2 citations

Review

Published on 26 Feb 2025

Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology

in Developmental and Reproductive Toxicology

Isaac Karimi
Layth Jasim Mohammad
A. Suvitha
Zohreh Haidari
Helgi B. Schiöth

Frontiers in Toxicology

doi 10.3389/ftox.2025.1477822

2,663 views
1 citation

Systematic Review

Published on 17 Oct 2024

A systematic review and meta-analysis of the impact of triclosan exposure on human semen quality

in Developmental and Reproductive Toxicology

Cecilia Adedeji Adegbola
Tunmise Maryanne Akhigbe
Adetomiwa Ezekiel Adeogun
Eva Tvrdá
Alica Pizent
Roland Eghoghosoa Akhigbe

Frontiers in Toxicology

doi 10.3389/ftox.2024.1469340

2,580 views
3 citations

Perspective

Published on 11 Oct 2024

Reproductive toxicology: keeping up with our changing world

in Developmental and Reproductive Toxicology

Laura B. Miller
Morgan B. Feuz
Ralph G. Meyer
Mirella L. Meyer-Ficca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1456687

5,564 views

Original Research

Published on 01 Oct 2024

Assessment of the effects of cannabidiol and a CBD-rich hemp extract in Caenorhabditis elegans

in Developmental and Reproductive Toxicology

Jessica A. Camacho
Bonnie Welch
Martine Ferguson
Estatira Sepehr
Cory Vaught
Yang Zhao
Suzanne Fitzpatrick
Jeffrey Yourick
Robert L. Sprando
Piper Reid Hunt

Frontiers in Toxicology

doi 10.3389/ftox.2024.1469341

14,088 views
1 citation

Perspective

Published on 16 Sep 2024

Light pollution: time to consider testicular effects

in Developmental and Reproductive Toxicology

Peter Y. Liu

Frontiers in Toxicology

doi 10.3389/ftox.2024.1481385

3,593 views

Original Research

Published on 02 Sep 2024

Developmental toxicity and estrogenic activity of antimicrobial phenolic-branched fatty acids using in silico simulations and in vivo and in vitro bioassay

in Developmental and Reproductive Toxicology

Xinwen Zhang
Helen Ngo
Karen Wagner
Xuetong Fan
Changqing Wu

Frontiers in Toxicology

doi 10.3389/ftox.2024.1380485

1,540 views
1 citation

Review

Published on 22 Aug 2024

Stem cell-based approaches for developmental neurotoxicity testing

in Developmental and Reproductive Toxicology

Joy Ku
Prashanth Asuri

Frontiers in Toxicology

doi 10.3389/ftox.2024.1402630

2,712 views
1 citation