Frontiers in Toxicology | Neurotoxicology

Original Research

Published on 16 Jan 2026

The lack of efficacy of tirzepatide in mitigating cisplatin-induced neurotoxicity and cognitive impairment in rats

in Neurotoxicology

Hanan Mubarak Almutairi
Ahmad Hamad Alhowail

Frontiers in Toxicology

doi 10.3389/ftox.2026.1752511

741 views

Original Research

Published on 12 Jan 2026

Role of bisphenol A in the aberrant activation of ionotropic glutamate transporters in the cerebral cortex and altered behavioral responses in C57BL/6J mice

in Neurotoxicology

Jasim Khan
Mohammad Waseem
Kajal Kamble
Suhel Parvez
Basu Dev Banerjee
Sarika Gupta
Sheikh Raisuddin

Frontiers in Toxicology

doi 10.3389/ftox.2025.1680589

751 views

Original Research

Published on 20 Nov 2025

Nose-to-brain translocation of inhaled ultrafine elongated particles: facts and mysteries

in Neurotoxicology

U. M. Graham
J. M. Pinto
J. Weuve
A. K. Dozier
R. Rogers
S. Nag
J. Schneider
J. D. Kaufman
D. A. Bennett
G. Oberdörster

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655149

2,306 views
4 citations

Original Research

Published on 05 Nov 2025

Exposure to the herbicide glyphosate leads to inappropriate threat responses and alters gut microbial composition

in Neurotoxicology

Mauricio Cáceres-Chacón
Osmarie Martínez-Guzmán
Héctor A. Haddock-Martínez
Alexdiel Figueroa-Pérez
Sian Rodríguez-Rosado
Jaleniz Suárez-Pérez
Raúl Y. Ramos-Sánchez
Filipa Godoy-Vitorino
Demetrio Sierra-Mercado

Frontiers in Toxicology

doi 10.3389/ftox.2025.1704231

2,270 views

Original Research

Published on 17 Oct 2025

Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish

in Neurotoxicology

Lindsey St. Mary
Ryan McClure
Lisa Truong
Steven J. Carrell
Katrina M. Waters
Robyn L. Tanguay

Frontiers in Toxicology

doi 10.3389/ftox.2025.1675060

1,784 views

Review

Published on 19 Sep 2025

Environmental exposure pathways of microplastics and their toxic effects on ecosystems and the nervous system

in Neurotoxicology

Kuo Lu
Yixiang Que
Longfei Wang
Yanfan Wang
Jinyan Qiu
Yangyang Jia
Cong Ding
Dazhong Wang
Weyland Cheng
Yaodong Zhang

Frontiers in Toxicology

doi 10.3389/ftox.2025.1649282

3,932 views
1 citation

Original Research

Published on 14 Jul 2025

Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

in Neurotoxicology

Douae Benloughmari
Samir Bikri
Meriam El Aboubi
Fatima-Zahra Yassif
Youssef Aboussaleh

Frontiers in Toxicology

doi 10.3389/ftox.2025.1610720

1,950 views

Original Research

Published on 10 Jul 2025

Arsenic toxicity in the Drosophila brain at single cell resolution

in Neurotoxicology

Anurag Chaturvedi
Vijay Shankar
Bibhu Simkhada
Rachel A. Lyman
Patrick Freymuth
Elisabeth Howansky
Katelynne M. Collins
Trudy F. C. Mackay
Robert R. H. Anholt

Frontiers in Toxicology

doi 10.3389/ftox.2025.1636431

2,995 views

Original Research

Published on 01 Apr 2025

Promising protective potential of MiR-103a-3p against polystyrene microplastic neurotoxicity in rats

in Neurotoxicology

Leila Mohammadi
Tourandokht Baluchnejadmojarad
Mina Goudarzi
Vahid Khodashenas
Roya Khoshravesh
Mehrdad Roghani

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560980

3,770 views
4 citations

Editorial

Published on 18 Feb 2025

Editorial: Model organisms in toxicology

in Neurotoxicology

Michael Aschner
Asok K. Dasmahapatra
Arantza Muriana

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560492

2,595 views
2 citations

Review

Published on 27 Jan 2025

The neurotoxicity of iodoacetic acid, a byproduct of drinking water disinfection

in Neurotoxicology

Xu Wang
Chunshu Rong
Ping Niu
Wei Leng
Gaihua Wang
Ziqiao He
Xin Qi
Dexi Zhao
Jinhua Li

Frontiers in Toxicology

doi 10.3389/ftox.2025.1543374

2,777 views
1 citation

Methods

Published on 10 Jan 2025

A primary rat neuron-astrocyte-microglia tri-culture model for studying mechanisms of neurotoxicity

in Neurotoxicology

Jessie R. Badley
Aishwarya Bhusal
Pamela J. Lein

Frontiers in Toxicology

doi 10.3389/ftox.2024.1523387

4,142 views

Original Research

Published on 03 Dec 2024

The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses

in Neurotoxicology

Dustyn Barnette
Amy L. Inselman
Pravin Kaldhone
Grace S. Lee
Kelly Davis
Sumit Sarkar
Pritpal Malhi
J. Edward Fisher
Joseph P. Hanig
Richard D. Beger

Frontiers in Toxicology

doi 10.3389/ftox.2024.1452974

2,680 views
1 citation

Editorial

Published on 22 Oct 2024

Editorial: Global excellence in Toxicology: Central and South America

in Neurotoxicology

Miriam Beatriz Virgolini
Ricardo Bastos Cunha

Frontiers in Toxicology

doi 10.3389/ftox.2024.1494491

3,876 views
1 citation

Mini Review

Published on 02 Sep 2024

A rare case of early onset lewy body dementia with parkinsonism associated with chronic exposure to copper contaminated drinking water

in Neurotoxicology

Marcia H. Ratner
Jonathan S. Rutchik

Frontiers in Toxicology

doi 10.3389/ftox.2024.1451235

4,897 views
3 citations

Original Research

Published on 16 Aug 2024

Effect of altered production and storage of dopamine on development and behavior in C. elegans

in Neurotoxicology

Irene Lee
Ava C. Knickerbocker
Charlotte R. Depew
Elizabeth L. Martin
Jocelyn Dicent
Gary W. Miller
Meghan L. Bucher

Frontiers in Toxicology

doi 10.3389/ftox.2024.1374866

3,824 views
4 citations

Original Research

Published on 06 Aug 2024

Decreased activity in zebrafish larvae exposed to glyphosate-based herbicides during development—potential mediation by glucocorticoid receptor

in Neurotoxicology

S. Spulber
L. Reis
P. Alexe
S. Ceccatelli

Frontiers in Toxicology

doi 10.3389/ftox.2024.1397477

2,386 views
2 citations

Original Research

Published on 05 Aug 2024

Hypoactivity and neurochemical alterations in the basal ganglia of female Sprague-Dawley rats after repeated exposure to atrazine

in Neurotoxicology

Triana Acevedo-Huergo
Jonathan Sánchez-Yépez
María Soledad Mendoza-Trejo
Isela Hernández-Plata
Magda Giordano
Verónica Mireya Rodríguez

Frontiers in Toxicology

doi 10.3389/ftox.2024.1416708

2,159 views

Original Research

Published on 30 Apr 2024

Acute intoxication with diisopropylfluorophosphate promotes cellular senescence in the adult male rat brain

in Neurotoxicology

Yi-Hua Tsai
Eduardo A. González
Ana C. G. Grodzki
Donald A. Bruun
Naomi H. Saito
Danielle J. Harvey
Pamela J. Lein

Frontiers in Toxicology

doi 10.3389/ftox.2024.1360359

3,041 views
3 citations

Perspective

Published on 26 Apr 2024

New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project

in Neurotoxicology

Tamara Tal
Oddvar Myhre
Ellen Fritsche
Joëlle Rüegg
Kai Craenen
Kiara Aiello-Holden
Caroline Agrillo
Patrick J. Babin
Beate I. Escher
Hubert Dirven

Frontiers in Toxicology

doi 10.3389/ftox.2024.1359507

9,866 views
36 citations

Original Research

Published on 08 Jan 2024

Astrocyte DNA damage and response upon acute exposure to ethanol and corticosterone

in Neurotoxicology

Ana Laura Reyes-Ábalos
Magdalena Álvarez-Zabaleta
Silvia Olivera-Bravo
María Vittoria Di Tomaso

Frontiers in Toxicology

doi 10.3389/ftox.2023.1277047

3,132 views
4 citations

Editorial

Published on 04 Sep 2023

Editorial: Women in neurotoxicology: 2021

in Neurotoxicology

Monica Renee Langley
Alice Villalobos
Sarah Vecchio

Frontiers in Toxicology

doi 10.3389/ftox.2023.1248748

1,559 views

Original Research

Published on 26 Jun 2023

Comparative toxicity assessment of glyphosate and two commercial formulations in the planarian Dugesia japonica

in Neurotoxicology

S. Grace Fuselier
Danielle Ireland
Nicholas Fu
Christina Rabeler
Eva-Maria S. Collins

Frontiers in Toxicology

doi 10.3389/ftox.2023.1200881

5,510 views
12 citations

Editorial

Published on 10 Mar 2023

Editorial: Rising stars in neurotoxicology: 2021

in Neurotoxicology

Katharina Koch

Frontiers in Toxicology

doi 10.3389/ftox.2023.1172417

2,074 views