AUTHOR=Reyes-Camacho David , Pérez José Francisco , Vinyeta Ester , Aumiller Tobias , Criado-Mesas Lourdes , Folch Josep Maria , Van der Klis Jan Dirk , Solà-Oriol David 

TITLE=Phytogenic Compounds Supplemented to Gestating Hyperprolific Sows Affects the Gut Health-Related Gene Expression and Histological Responses in Neonate Piglets

JOURNAL=Frontiers in Veterinary Science

VOLUME=Volume 8 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2021.639719

DOI=10.3389/fvets.2021.639719

ISSN=2297-1769

ABSTRACT=This research aims to determine whether a specific blend of phytogenic compounds (BPC) supplemented in gestating hyperprolific sow diets can promote prenatal maternal effects in terms of piglet gut function and morphology. Twenty-eight (Landrace x Yorkshire) gilts and sows (parity 0 to 7) were randomly distributed by parity number and body weight into two dietary treatments: unsupplemented Control (CON) (n = 14) or CON diet supplemented with 1 g/kg feed of BPC during gestation (n = 14). The BPC supplementation during gestation of sows upregulated the newborn piglets’ jejunal gene expression of SOD2, SLC16A1, SLC11A2, SLC39A, ALPI, and DAO1, while IFN-γ, IDO1 and CLDN4 were downregulated (P < 0.10). In addition, the jejunal villus height and the ratio of the villus height to crypt depth tended to increase (P < 0.10), while goblet cell volume density was higher (P < 0.05) in BPC compared to CON. In conclusion, dietary supplementation of BPC in gestating diets for hyperprolific sows influences neonatal histomorphology and expression of genes related to the intestinal function and health.