AUTHOR=Gao Xing , Xire Luosong , Zhang Zhao , Quan Chuxian , Zhou Shimeng , Li Kewei , Song Rende , Zhao Suonan , Kong Xiangying , Naori Cairang , Kulyar Muhammad Fakhar-e-Alam , Bao Yuhua , Li Jiakui TITLE=Seroprevalence of Cystic Echinococcosis in Yaks and Sheep During 2017 on the Qinghai–Tibet Plateau, China JOURNAL=Frontiers in Veterinary Science VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.849500 DOI=10.3389/fvets.2022.849500 ISSN=2297-1769 ABSTRACT=Cystic echinococcosis (CE) is a livestock disease caused by parasites called Echinococcus granulosus (E. granulosus). It is one of the main reasons that causes illness and poor for herders on the Qinghai-Tibet plateau. Meanwhile, the Qinghai-Tibet plateau has been a key area for echinococcosis control in China. We determined the seroprevalence of E. granulosus in ruminants on the Qinghai-Tibet plateau, China. A total of 2730 serum samples (1638 serum samples from yaks, 1092 serum samples from sheep) were collected from the Plateau in 2017. The samples were assayed for E. granulosus antibodies by commercial enzyme-linked immunosorbent assay (ELISA) kits. Our results exhibited that the prevalence was 52.2% and 38.2% in yaks and Tibetan sheep, respectively. The results suggested that it had more chance to acquire E. granulosus infection for old animals due to the more exposure to contaminated the source of infection. However, no significant difference was observed among in Gender. Due to the rainfall and a lot of lakes, the ruminants had a higher risk of CE infection in Qinghai province, Qinglong and Baingoin. By the investigation, the prevalence and distribution of CE were basically clarified in yaks and Tibetan sheep on the Qinghai-Tibet plateau, which provided a basis for prevention and control of the disease.