AUTHOR=Singh Vikash K. , Neira Victor , Brito Barbara , Ariyama Naomi , Sturos Matt , Mor Sunil K. 

TITLE=Genetic Characterization of a Novel Bovine Rotavirus A G37P[52] Closely Related to Human Strains

JOURNAL=Frontiers in Veterinary Science

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.931477

DOI=10.3389/fvets.2022.931477

ISSN=2297-1769

ABSTRACT=Bovine Rotavirus A (boRVA) strains are common causative agents of diarrhea in calves, resulting in economic losses to the beef and dairy industry. Importantly, this virus has a zoonotic relevance due to its ability to reassort with human rotaviruses. In this study, fecal samples were collected from three calves with diarrhea during an outbreak on a dairy farm. The genetic material of boRVA was detected by real-time rtPCR in two samples. Then the virus in one of these positive samples was identified as a novel boRVA closely related with human rotavirus strains mainly from the USA based on whole-genome characterization. Astrovirus, norovirus, Escherichia coli, and Clostridium perfringens were also detected. However, we consider the novel boRVA as the etiological agent of the outbreak due to the lesions associated with the virus. Further studies are necessary to clarify the evolutionary advantages that novel rotavirus genotypes may have.