AUTHOR=Hidari Kyosuke , Nakamoto Yuya , Sakurai Keiichi , Sakurai Yoko , Nibe Kazumi , Nakamoto Miwa 

TITLE=Case report: Presumptive subcutaneous malignant peripheral nerve sheath tumor with intracranial invasion and osteolysis in the posterior fossa of a dog

JOURNAL=Frontiers in Veterinary Science

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.977099

DOI=10.3389/fvets.2022.977099

ISSN=2297-1769

ABSTRACT=A 13-year-old castrated male Toy Poodle presented with an acute vestibular disorder. Magnetic resonance imaging and computed tomography revealed a sizeable solitary tumor in the occipital area with intracranial and extracranial lesion formation. Histopathological and immunohistochemical examinations led to a strong suspicion of malignant peripheral nerve sheath tumor. We commenced palliative treatment. However, his condition rapidly deteriorated, and he died 19 days after the onset of clinical signs. Our report is the first report of a malignant peripheral nerve sheath tumor-forming intracranial and extracranial lesions with bone destruction in dogs.