AUTHOR=Muñoz Mariela , del Sol Mariano , Vásquez Bélgica TITLE=Antibacterial and wound-healing action of Ulmo honey (Eucryphia cordifolia) of differing degrees of purity JOURNAL=Frontiers in Veterinary Science VOLUME=Volume 10 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2023.1172025 DOI=10.3389/fvets.2023.1172025 ISSN=2297-1769 ABSTRACT=Antibacterial properties of honey vary according to its floral origin; few studies report percentage of pollen types in honey, making it difficult to reproduce and compare results. This study compares the antibacterial and wound healing properties of three monofloral Ulmo honeys with different percentages of pollen from Eucryphia cordifolia. The pollen percentage of the honeys was determined by melissopalynological analysis and they were classified into 3 groups: M1 (52.77% of pollen from Eucryphia cordifolia), M2 (68.41%) and M3 (82.80%) They were subjected to chemical analysis and agar diffusion test against Staphylococcus aureus. Twenty healthy adult guinea pigs (Cavia porcellus) of both sexes were randomly assigned to 4 groups for experimental burns skin wound (uninfected) production and treatment with Ulmo honey. On day 10 post injury, biopsies were obtained and histological analysis was performed to assess wound healing capacity following treatment with honey. The chemical analysis showed that M3 differed significantly from M1 in terms of pH (P=0,020), moisture (P=0,020), total sugars (P=0,034) and total solids (P=0,020). Both strains of Staphylococcus aureus were susceptible to M1 and M2 at 40% w/v but were resistant to M3 at all concentrations. All groups (I-IV) were in the initial proliferative phase, with complete or partial re-epithelization of the epidermis. Antibacterial activity showed a wide range of variation in the honeys studied, with no significant differences between wound healing and pollen percentage in the groups studied. Higher pH and the absence of Tineo in M3 confer a lower antibacterial capacity but not a lower wound healing capacity. Despite its variability in the percentage of Eucryphia cordifolia like primary pollen in Ulmo's monofloral honey, this has the same properties in relation to wound healing.