AUTHOR=Zhao Ruo-Han , Yang Fang-Xiao , Bai Yi-Cheng , Zhao Jing-Ying , Hu Mei , Zhang Xin-Yan , Dou Teng-Fei , Jia Jun-Jing 

TITLE=Research progress on the mechanisms underlying poultry immune regulation by plant polysaccharides

JOURNAL=Frontiers in Veterinary Science

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2023.1175848

DOI=10.3389/fvets.2023.1175848

ISSN=2297-1769

ABSTRACT=In recent years, increasing interest has focused on natural components extracted from plants, among which plant polysaccharides have been highlighted because of their various biological activities. Plant polysaccharides are natural immunomodulators that can promote the growth of immune organs, activate immune cells and the complement system, and release cytokines. As a green feed additive, plant polysaccharides can not only relieve stress and enhance the immunity and disease resistance of poultry but also regulate the balance of intestinal microorganisms. This paper reviews the immunomodulatory effects and molecular mechanisms of different plant polysaccharides (Atractylodes macrocephala Koidz polysaccharide, Astragalus polysaccharides, Taishan Pinus massoniana pollen polysaccharide, and alfalfa polysaccharide) in poultry. Current research results reveal that plant polysaccharides have potential uses as therapeutic agents for poultry immune abnormalities and related diseases.