AUTHOR=Steblaj Barbara , Galli Jasmin , Torgerson Paul , Kutter Annette 

TITLE=Evaluation of leukocyte depletion of packed red blood cell units and impact on clinically observed transfusion reactions

JOURNAL=Frontiers in Veterinary Science

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2023.1217575

DOI=10.3389/fvets.2023.1217575

ISSN=2297-1769

ABSTRACT=The aim of this retrospective study was to determine whether there is an association between leukoreduction of packed red blood cell (pRBC) units and reduction of clinically observed transfusion reactions (TR), particularly febrile non-haemolytic transfusion reactions (FNHTR), and better outcomes in dogs. Secondary aims were to evaluate the effects of other factors suspected to influence transfusion reaction frequency or survival, including crossmatching, use of immunosuppressive drugs and age and number of the blood products being administered.Materials and methods: Medical data on dogs transfused with leukocyte-reduced (LR) and nonleukocyte-reduced (N-LR) pRBC units at the *, *