AUTHOR=Suwanpakdee Sarin , Ketchim Natthaphat , Thongdee Metawee , Chaiwattanarungruengpaisan Somjit , Tangsudjai Siriporn , Wiriyarat Witthawat , Julapanthong Pruksa , Trakoolchaisri Wachira , Buamas Supakit , Sakcamduang Walasinee , Okada Pilailuk Akkapaiboon , Puthavathana Pilaipan , Paungpin Weena TITLE=Sero-epidemiological investigation and cross-neutralization activity against SARS-CoV-2 variants in cats and dogs, Thailand JOURNAL=Frontiers in Veterinary Science VOLUME=Volume 11 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1329656 DOI=10.3389/fvets.2024.1329656 ISSN=2297-1769 ABSTRACT=Epidemiological data on SARS-CoV-2 infection in companion animals has been thoroughly investigated in many countries. However, the information on the neutralizing cross-reactivity against SARS-CoV-2 variants in companion animals is still limited. Here, we explored the neutralizing antibodies against SARS-CoV-2 in cats and dogs between May 2020 and December 2021 during the first wave (a Wuhan-Hu-1-dominant period) and the fourth waves (a Delta-dominant period) of the Thailand COVID-19 outbreak. Archival plasma samples of 1304 cats and 1795 dogs (total = 3099) submitted for diagnosis and health check were collected at the